Hazel Inskip
A5091766588- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Bone health and osteoporosis research
- Vitamin D Research Studies
- Nutritional Studies and Diet
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Breastfeeding Practices and Influences
- Health, Environment, Cognitive Aging
- Child Nutrition and Water Access
- Epigenetics and DNA Methylation
- Physical Activity and Health
- Food Security and Health in Diverse Populations
- Body Composition Measurement Techniques
- Child and Adolescent Health
- Health disparities and outcomes
- Child Nutrition and Feeding Issues
- Folate and B Vitamins Research
- Fatty Acid Research and Health
- Health Systems, Economic Evaluations, Quality of Life
- Cancer Risks and Factors
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Dermatology and Skin Diseases
MRC Lifecourse Epidemiology Unit
2015-2024
University of Southampton
2015-2024
NIHR Southampton Biomedical Research Centre
2015-2024
University Hospital Southampton NHS Foundation Trust
2015-2024
MRC Epidemiology Unit
2000-2024
Southampton General Hospital
2014-2023
Medical Research Council
2013-2022
National Institute for Health Research
2014-2022
National Health Service
2014-2022
University of Liverpool
2021
The excess mortality of schizophrenia is well recognised, but its precise causes are not understood.To measure the standardised ratio (SMR) and examine reasons for any in a community cohort with schizophrenia.We carried out 13-year follow-up 370 patients schizophrenia, identifying those who died their circumstances.Ninety-six per cent was traced. There were 79 deaths. SMRs all (298), natural (232) unnatural (1273), significantly higher than to be expected general population, as disease...
Fixed genomic variation explains only a small proportion of the risk adiposity. In animal models, maternal diet alters offspring body composition, accompanied by epigenetic changes in metabolic control genes. Little is known about whether such processes operate humans.Using Sequenom MassARRAY we measured methylation status 68 CpGs 5' from five candidate genes umbilical cord tissue DNA healthy neonates. Methylation varied greatly at particular CpGs: for 31 with median ≥5% and 5-95% range...
People with schizophrenia have significantly raised mortality but we do not know how these patterns in the UK changed since 1990s.To measure 25-year of people particular focus on changes over time.Prospective record linkage study a community cohort 370 schizophrenia.The had an all-cause standardised ratio 289 (95% CI 247-337). Most deaths were from common causes seen general population. Unnatural concentrated first 5 years follow-up. There was indication that cardiovascular may increased...
Saw Swee Hock School of Public Health, National University Singapore, Department Paediatrics, Yong Loo Lin Medicine, Obstetrics & Gynaecology, Health System, Singapore Institute for Clinical Sciences, Agency Science and Technology Research (A*STAR), Brenner Centre Molecular Liggins Institute, Auckland, New Zealand, Medical Council Lifecourse Epidemiology Unit, Southampton, UK, NIHR Southampton Biomedical Centre, Hospital NHS Foundation Trust, Biostatistics KK Women’s Children’s Hospital,
Little is known about preschool-aged children’s levels of physical activity (PA) over the course day. Using time-stamped data, we describe and patterns PA in a population-based sample four-year-old British children. Within Southampton Women’s Survey 593 4-year-old children (51% female) were measured using (Actiheart) accelerometry for up to 7 days. Three outcome measures: minutes spent sedentary (<20 cpm); light (LPA: ≥20 – 399 cpm) moderate-to-vigorous (MVPA: ≥400 derived. Average daily...
Recent findings suggest that maternal vitamin D insufficiency during pregnancy has consequences for the offspring's bone health in later life. To investigate whether affects fetal femur growth ways similar to those seen childhood rickets and study timing gestation of any effect status, we studied 424 pregnant women within a prospective longitudinal nutrition lifestyle before (Southampton Women's Survey). Using high-resolution 3D ultrasound, measured length distal metaphyseal cross-sectional...
In contrast to our knowledge about the number of cancers attributed smoking, alcohol is poorly understood by public. We estimate increase in absolute risk cancer (number cases per 1000) moderate levels alcohol, and compare these low creating a 'cigarette-equivalent population harm'. Alcohol tobacco attributable fractions were subtracted from lifetime general risks developing alcohol- smoking-related cancers, alcohol-abstaining non-smokers. This was multiplied relative drinking ten units or...
Abstract Background During the past 25 years, many pregnancy and birth cohorts have been established. Each cohort provides unique opportunities for examining associations of early‐life exposures with child development health. However, to fully exploit large amount available resources facilitate cross‐cohort collaboration, it is necessary accessible information on each its individual characteristics. The aim this work was provide an overview European registered in a freely database located at...
Maternal vitamin D status has been associated with bone mass of offspring in many, but not all, observational studies. However, maternal repletion during pregnancy yet proven to improve a randomised controlled trial. We aimed assess whether neonates born mothers supplemented have greater whole-body mineral content (BMC) at birth than those who had received supplementation.The Vitamin Osteoporosis Study (MAVIDOS) was multicentre, double-blind, randomised, placebo-controlled trial that...
Genome-wide association studies of birth weight have focused on fetal genetics, whereas relatively little is known about the role maternal genetic variation. We aimed to identify variants associated with that could highlight potentially relevant determinants growth. meta-analysed data up 8.7 million SNPs in 86 577 women European descent from Early Growth Genetics (EGG) Consortium and UK Biobank. used structural equation modelling (SEM) analyses mother-child pairs quantify separate effects....