A5016230593- Ultrasound in Clinical Applications
- AI in cancer detection
- COVID-19 diagnosis using AI
- Radiomics and Machine Learning in Medical Imaging
- Radiation Dose and Imaging
- Radiology practices and education
- Thyroid Cancer Diagnosis and Treatment
- Hip disorders and treatments
- Pleural and Pulmonary Diseases
- Renal and Vascular Pathologies
- Advanced X-ray and CT Imaging
- Congenital Diaphragmatic Hernia Studies
- Pediatric Urology and Nephrology Studies
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Digital Imaging for Blood Diseases
- Abdominal Trauma and Injuries
- Ethics and Legal Issues in Pediatric Healthcare
- Medical Imaging and Analysis
- Orthopaedic implants and arthroplasty
- Urological Disorders and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Artificial Intelligence in Healthcare and Education
- Neuroblastoma Research and Treatments
- Tracheal and airway disorders
National University Hospital
2016-2025
National University of Singapore
2013-2024
National University Health System
2013-2021
University Health System
2021
Medical Research Institute of New Zealand
2017
Khoo Teck Puat Hospital
2017
University of Southampton
2013
Singapore Institute for Clinical Sciences
2013
NIHR Southampton Biomedical Research Centre
2013
Agency for Science, Technology and Research
2013
Saw Swee Hock School of Public Health, National University Singapore, Department Paediatrics, Yong Loo Lin Medicine, Obstetrics & Gynaecology, Health System, Singapore Institute for Clinical Sciences, Agency Science and Technology Research (A*STAR), Brenner Centre Molecular Liggins Institute, Auckland, New Zealand, Medical Council Lifecourse Epidemiology Unit, Southampton, UK, NIHR Southampton Biomedical Centre, Hospital NHS Foundation Trust, Biostatistics KK Women’s Children’s Hospital,
There is a crucial need for quick testing and diagnosis of patients during the COVID-19 pandemic. Lung ultrasound an imaging modality that cost-effective, widely accessible, can be used to diagnose acute respiratory distress syndrome in with COVID-19. It find important characteristics images, including A-lines, B-lines, consolidation, pleural effusion, which all inform clinician monitoring diagnosing disease. With use portable transducers, lung images easily acquired, however, are often poor...
Abstract Background Fifty years since its inception, Light's criteria have aided in classifying pleural effusions (PEs) as exudates if 1 or more are met. Thoracic ultrasound (US) emerges a non‐invasive technique for point of care use especially procedures contemplated. Objective We aimed to develop score based on radiological and US features that could separate from transudates without serum fluid biochemical tests necessary criteria. Methods A prospective review consecutive patients with PE...
Introduction The aim of this study was to establish institutional diagnostic reference levels (DRLs) by summarising doses collected across the five computed tomography (CT) system in our institution. Methods CT dose data 15940 patients were retrospectively from May 2015 October scanners. mean, 75th percentile and 90th spread calculated according anatomic region. common examinations such as head, chest, combined abdomen/pelvis (A/P), chest/abdomen/pelvis (C/A/P) reviewed. Distribution index...
Purpose To validate accuracy of diagnosis developmental dysplasia the hip (DDH) from geometric properties acetabular shape extracted three-dimensional (3D) ultrasonography (US). Materials and Methods In this retrospective multi-institutional study, 3D US was added to conventional two-dimensional (2D) 1728 infants (mean age, 67 days; age range, 3-238 days) evaluated for DDH January 2013 December 2016. Clinical after more than 6 months follow-up normal (n = 1347), borderline (Graf IIa, later...
A-lines and B-lines are key ultrasound markers that differentiate normal from abnormal lung conditions. horizontal lines usually seen in aerated lungs, while linear vertical artifacts associated with abnormalities such as pulmonary edema, infection, COVID-19, where a higher number of indicates more severe pathology. This paper aimed to evaluate the effectiveness newly released AI tool (ExoLungAI) detection quantification/detection help clinicians assessing
Background: Ultrasound for developmental dysplasia of the hip (DDH) is challenging nonexperts to perform and interpret. Recording “sweep” images allows more complete assessment, suitable automation by artificial intelligence (AI), but reliability has not been established. We assessed agreement between readers varying experience a commercial AI algorithm, in DDH detection from infant ultrasound sweeps. Methods: selected full spectrum poor-to-excellent quality normal severe dysplasia, 240 hips...
The advent of immune checkpoint targeted immunotherapy has seen a spectrum immune-related phenomena in both tumor responses and toxicities. We describe case pseudoprogression that pushes the limits response criteria challenges boundaries definitions set by trial protocols. A middle-aged man with conventional clear cell renal carcinoma (RCC) had received multiple prior systemic treatments including vascular endothelial growth factor receptor tyrosine kinase inhibitors, as well surgeries...
Lower vitamin D status has been associated with adiposity in children through adults. However, the evidence of impact maternal vitamin-D during pregnancy on offspring's is mixed. The objective this study was to examine associations between [25(OH)D] at mid-gestation and neonatal abdominal adipose tissue (AAT) compartments, particularly deep subcutaneous linked metabolic risk. Participants (N = 292) were Asian mother-neonate pairs from mother-offspring cohort, Growing Up Singapore Towards...
Peritoneal lymphomatosis, a rare presentation of lymphoma, can mimic peritoneal carcinomatosis.Computed tomography findings in both conditions include omental caking, as well enhancement, thickening and nodularity.We report three cases lymphomatosis give an analysis the salient imaging features that aided accurate diagnosis condition each case.Two demonstrated elevated serum cancer antigen 125 levels, marker commonly associated with ovarian carcinoma.It is thus critical to distinguish from...
Ultrasound (US) has been an important tool for evaluating and imaging renal pathology in children. Development of US contrast agents dedicated software the detection microbubbles given this radiological investigation a new dimension, especially children with impairment. Application contrast-enhanced (CEUS) brings into domain historically occupied by computed tomography magnetic resonance imaging. We retrospectively studied nine who had undergone CEUS (age range 3–16 years). This pictorial...
Immobility of the lower extremity due to medical conditions such as stroke can lead complications deep vein thrombosis or ankle contracture, and thereafter prolonged recovery process patients. In this preliminary clinical study, we aimed examine effect a novel soft robotic sock device, capable providing assisted exercise, in improving blood flow limb prevent complication strokes joint contracture.Stroke patients were recruited (n = 17) compare using conventional pneumatic compression device...
PURPOSE: To determine the accuracy of a handheld ultrasound-guided optoacoustic tomography (US-OT) probe developed for human deep-tissue imaging in ex vivo assessment tumor margins postlumpectomy. METHODS: A custom-built two-dimensional (2D) US-OT–handheld was used to scan 15 lumpectomy breast specimens. Optoacoustic signals acquired at multiple wavelengths between 700 and 1100 nm were reconstructed using model linear algorithm, followed by spectral unmixing lipid deoxyhemoglobin (Hb)....
We present a soft robotic sock device developed to provide assistance in ankle dorsiflexion and plantarflexion of stroke patients who are at high risk developing deep vein thrombosis. The actuators extend when infused with pressurized air, so as guide the into motion. On other hand, contract back their initial length deflated pull dorsiflexion. In this work, were characterized terms linear displacement-pressure relationship zero strain well force-pressure 100% strain. was also evaluated on...