A5065301851- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Family and Disability Support Research
- Child Nutrition and Feeding Issues
- Congenital Diaphragmatic Hernia Studies
- Neonatal and fetal brain pathology
- Child and Adolescent Health
- Neuroscience of respiration and sleep
- Autism Spectrum Disorder Research
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Child Nutrition and Water Access
- Assisted Reproductive Technology and Twin Pregnancy
- Language Development and Disorders
- Reading and Literacy Development
- Pharmaceutical Practices and Patient Outcomes
- Gestational Diabetes Research and Management
- Maternal Mental Health During Pregnancy and Postpartum
- Congenital Anomalies and Fetal Surgery
- Infant Nutrition and Health
- Child Development and Digital Technology
- Breastfeeding Practices and Influences
- Child and Adolescent Psychosocial and Emotional Development
- Child Abuse and Trauma
- Early Childhood Education and Development
KK Women's and Children's Hospital
2016-2025
SingHealth Duke-NUS Academic Medical Centre
2024
Duke-NUS Medical School
2020-2024
SingHealth Polyclinics
2019
Nassau University Medical Center
2011-2016
Sawai ManSingh Medical College and Hospital
2016
Mount Elizabeth Novena Hospital
2016
London Rebuilding Society
2014
National University of Singapore
2013
Christian Medical College & Hospital
2013
Saw Swee Hock School of Public Health, National University Singapore, Department Paediatrics, Yong Loo Lin Medicine, Obstetrics & Gynaecology, Health System, Singapore Institute for Clinical Sciences, Agency Science and Technology Research (A*STAR), Brenner Centre Molecular Liggins Institute, Auckland, New Zealand, Medical Council Lifecourse Epidemiology Unit, Southampton, UK, NIHR Southampton Biomedical Centre, Hospital NHS Foundation Trust, Biostatistics KK Women’s Children’s Hospital,
Developmental delays are common in childhood, occurring 10%-15% of preschool children. Global developmental less common, 1%-3% identified during routine checks by the primary care physician or when parent raises concerns. Assessment for delay settings should include a general and systemic examination, including plotting growth centiles, hearing vision assessment, baseline blood tests if deemed necessary, referral to paediatrician, counselling parents. It is important follow up with parents...
Comparisons of cognitive processing in monolinguals and bilinguals have revealed a bilingual advantage inhibitory control. Recent studies demonstrated advantages associated with exposure to two languages infancy. However, the domain specificity scope infant infancy remains unclear. In present study, 114 monolingual infants were compared very basic task information processing—visual habituation—at 6 months age. Bilingual greater efficiency stimulus encoding as well improved recognition memory...
Aim To evaluate the predictive and concurrent diagnostic agreement of Ages Stages Questionnaire 3rd Edition (ASQ‐3) with Bayley Scales Infant Toddler Development (Bayley‐III) in infants born preterm very‐low‐birthweight (PT/VLBW; ≤1250g). Method We evaluated 141 PT/VLBW (68 males, 73 females) at KK Women's Children's Hospital between January 2010 December 2011, to determine ASQ‐3 9, 12, 18, 24 months corrected age Bayley‐III months. Cut‐offs on were estimated by receiver operating...
Primary outcome was to compare neurodevelopmental at two years in intracytoplasmic sperm injection (ICSI) conceived children versus matched controls. Secondary determine incidence of major congenital malformations and study perinatal outcome.Prospective cohort study.Tertiary care centre over a period 13 months.Seventy-six ICSI 261 controls selected by matching for maternal age, sex, date delivery, race, plurality parity.Mental Development Index (MDI) Psychometric (PDI) the Bayley's Scale...
To study effectiveness of quality improvement interventions in reducing hypothermia preterm infants on admission to neonatal intensive care unit. Quality methodologies including multidisciplinary planning and implementation evidence-based interventions. Data during post-implementation were collected. In total, 84 with birth weights ≤ 1500 g delivered period (October 2008–April 2009) compared 168 historical controls 947 the subsequent 4 years. addition routine interventions, delivery room...
Child development refers to the continuous but predictably sequential biological, psychological and emotional changes that occur in human beings between birth end of adolescence. Developmental surveillance should be incorporated into every child visit. Parents play an important role child's developmental assessment. The primary care physician educate encourage parents use checklist health booklet monitor their development. Further evaluation is necessary when delay identified. This article...
The world population is becoming older now. boom of the elderly comes from public health efforts to improve living conditions and prevent disease, improved medical interventions. People more than 65-year-old who are representing 12.9% now expected grow be 19% by 2030. Very few numbers diseases will have such socioeconomic burden on society in newer world. Although Alzheimer's disease (AD) has been studied very well recently, still its exact etiopathogenesis unknown. Currently there no...
This study assesses the trends and predictors of mortality morbidity in infants gestational age (GA) <27 weeks from 1990 to 2007.This is a retrospective cross-sectional cohort infant deliveries between 2007 largest perinatal centre Singapore. born at 2 Epochs (Epoch 1 (E1):1990 1998, Epoch (E2):1999 2007) using logistic regression models identify factors associated with composite morbidity. The main outcomes that were measured morbidity.Four hundred eight out 615 (66.3%) live 22 26 survived...
Late preterm (LP) neonates (34 to 36 weeks gestation) are often managed like term though current literature has identified them have greater complications. The primary objective of our study was evaluate and compare morbidity resource utilisation in LPs especially view paucity Asian studies this regard.A retrospective audit carried out on 12,459 born KK Women's Children's Hospital (KKWCH). chief outcome measures were hypoglycaemia, hypothermia, respiratory morbidity, feeding problems...
Background: The home literacy environment (HLE) and joint parent–child book reading are key factors in children’s language acquisition. Child-centered orientation (CCLO) refers to the child’s level of engagement events. Aim: To describe HLE identify demographic variables associated with a poor CCLO at 12 months age. Methods: Parents Singaporean children enrolled Growing Up Singapore Towards healthy Outcomes (GUSTO; n = 1152, birth cohort 2009–2010) completed childhood questionnaire obtain...
BackgroundWith increasing acceptance of universal developmental screening in primary care, it is essential to evaluate the local validity and psychometric properties commonly used questionnaires like parent-completed Ages Stages Questionnaires, 3rd Edition (ASQ-3) identifying delays. The aim this study assess convergent ASQ-3 with Bayley Scales Infant Development-3rd edition (Bayley-III) delay a low-risk term cohort Singapore.MethodsASQ-3 Bayley-III data was collected prospectively...
Objective : The aim of the present prospective cohort study was to evaluate relationship between lower respiratory tract colonization with Ureaplasma urealyticum and development chronic lung disease (CLD) in a high‐risk neonatal population. Methods Prospective preterm infants birthweight < 1500 g needing mechanical ventilation within 24 h birth tertiary care unit. Endotracheal aspirates from these were cultured for U. rate determined. primary outcome measure incidence CLD at 28 days life....
Background: The aim was to evaluate the ability of customized and cohort birthweight standards in discriminating intrauterine growth retardation (IUGR).Methods: Birthweights (BWs) GUSTO singleton infants born at gestational age (GA) 35–41 weeks were converted using two standards: (a) cohort-based BW centile adjusted for GA baby gender; (b) percentile calculator maternal height weight, race, parity, gender. Infants classified into three groups: (1) < 10th by customization– customized-SGA, (2)...
Introduction: This study aimed to evaluate the prevalence of developmental and emotional/behavioural concerns in maltreated children examine impact adverse family/caregiver risk factors on these outcomes. Method: We analysed family demographic baseline data 132 their caregivers from a support programme Singapore. examined associations 3 main (i.e. caregiver mental health, educational attainment socio-economic status [SES]) with developmental/behavioural outcomes using multivariable logistic...