A5012016039- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- Congenital Anomalies and Fetal Surgery
- Infant Nutrition and Health
- Down syndrome and intellectual disability research
- Urological Disorders and Treatments
- Child Nutrition and Feeding Issues
- Family and Disability Support Research
- Disability Education and Employment
- Vascular Malformations and Hemangiomas
- Salmonella and Campylobacter epidemiology
- Breastfeeding Practices and Influences
- Respiratory viral infections research
- Infant Development and Preterm Care
- Listeria monocytogenes in Food Safety
- Clinical Nutrition and Gastroenterology
- Lymphatic Disorders and Treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Childhood Cancer Survivors' Quality of Life
- Ethics and Legal Issues in Pediatric Healthcare
- Viral gastroenteritis research and epidemiology
- Chronic Disease Management Strategies
- Gastrointestinal disorders and treatments
- Medical Coding and Health Information
- Neuroscience of respiration and sleep
National University of Singapore
2019-2022
Duke-NUS Medical School
2019-2022
Singapore College of Traditional Chinese Medicine
2020-2022
KK Women's and Children's Hospital
2016-2022
Nanyang Technological University
2020-2022
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in preterm infants. Survivors may suffer both short- and long-term morbidities. Current evidence suggests that incidence of NEC can be reduced by standardizing care delivery addressing key risk factors including an altered gut microbiome, use formula milk, hyperosmolar feeds, unrestricted high-risk medications METHODS: Since 2014, department has a workgroup who analyzed all cases within month diagnosis to identify...
Congenital chylous ascites is a rare cause of in newborn infants. Its aetiology varies from localised leaky lymphatic duct to genetic syndromes. Most these cases have transient resolving over time with conservative management but some may progress needing medical as well surgical treatment. We describe case antenatally detected large fetal necessitating abdominal paracentesis and amnioreduction. Marked respiratory distress at birth required urgent relieve symptoms. The infant initially...
Abstract A 20-year retrospective review at a tertiary hospital in Singapore identified 11 cases of perinatal listeriosis maternal–fetal pairs (incidence, 4.8 per 100 000 live births). Fever, meconium-stained amniotic fluid, and fetal akinesia during the third trimester were associated with listeriosis. In this study early directed antibiotic therapy resulted favorable outcomes.
Background: Perinatal Palliative Care provides comprehensive and holistic care for expectant new parents, who receive a diagnosis of life-limiting fetal condition opt to continue pregnancy their newborn infant. Aim: To develop service providing individually tailored during pregnancy, birth, postnatal bereavement period. Methods: Following baseline survey neonatologists discussions with key stakeholders we launched the at KK Women's Children's hospital, Singapore in January 2017. The...
Introduction: Extended hospitalization of low birth weight infants increases risk medical and psychosocial complications. Our aim was to reduce the length assess safety cost savings discharging at a 1900 g instead 2000 g, as has been practice. Methods: This is single-centre, nurse led quality improvement project done tertiary neonatal unit in Singapore with primary outcome reducing average stay selected infants. In phase 1, between 1000 1700 were discharged provided they met discharge...
The aim of this study is to compare neonatal mortality and morbidity in multiple singleton preterm/very low birthweight (PT/VLBW) multiethnic Asian infants.Cohort 676 299 PT/VLBW infants born between 2008 2012 at KK Women's Children's Hospital, the largest tertiary perinatal center Singapore with further stratification by gestational ages 23 25 (Group 1), 26 28 2), ≥29 3) weeks. Outcome measures included predischarge major morbidity.Overall survival discharge was comparable for singletons...
Physicians play a pivotal role in the management of children and adults with Down Syndrome. Achieving full developmental potential child Syndrome depends on prompt treatment medical complications, family support early establishment intervention programmes. The presence evidence-based guidelines physician both community restructured hospitals to provide timely appropriate recommendations. It will also aid counselling parents caregivers. Although most co-morbidity characteristics are common...
Globally, mental health disorders and behavioural problems afflict persons with Down syndrome (DS) a high prevalence reported in some studies. However, data on emotional DS cohort Asian countries are lacking.To assess the status of children adults DS, using Strength Difficulties Questionnaire (SDQ) its impact caregivers supplement.The questionnaires were administered to eligible participants aged ≥4 years. In addition, participant's ≥ 11 years old attempted self-report. Scoring was done as...
Necrotising enterocolitis (NEC) is a severe gastrointestinal disease mostly in premature infants due to intestinal necrosis. The aetiology of NEC multifactorial and includes gut immaturity, dysbiosis exaggerated mucosal reactivity microbial ligands. Radiographic evidence pneumatosis intestinalis has been critical feature for diagnosing Bell stage ≥IIA recommended treatment prolonged antibiotics (7–14 days) while off enteral feeds. Pneumatosis coli (Pcoli), mild or benign form NEC,...
<h3>Background</h3> Respiratory viral infections (RVI) among children with Down syndrome (DS) is a common cause of hospital admissions. Due to the underlying co-morbidities, severity and length hospitalization high in this population. <h3>Objectives</h3> We estimated described burden RVI admission infants within first 2 year life. <h3>Methods</h3> This single-centre cohort study that includes all diagnosed Syndrome our centre. Data on laboratory-confirmed were extracted from microbiology...