- Obesity, Physical Activity, Diet
- Esophageal and GI Pathology
- Gastroesophageal reflux and treatments
- Clinical Nutrition and Gastroenterology
- Child Nutrition and Feeding Issues
- Nutritional Studies and Diet
- Helicobacter pylori-related gastroenterology studies
- Tracheal and airway disorders
- Eosinophilic Esophagitis
- Intestinal Malrotation and Obstruction Disorders
- Physical Activity and Health
- Infant Nutrition and Health
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Dysphagia Assessment and Management
- Congenital Diaphragmatic Hernia Studies
- Liver Disease Diagnosis and Treatment
- Birth, Development, and Health
- Diet and metabolism studies
- Nutrition and Health in Aging
- Congenital Anomalies and Fetal Surgery
- Neonatal Respiratory Health Research
- Cystic Fibrosis Research Advances
- Health and Lifestyle Studies
- Childhood Cancer Survivors' Quality of Life
Centre Hospitalier Universitaire de Lille
2016-2025
Inserm
2016-2025
Institute for Translational Research in Inflammation
2017-2025
Hôpital Jeanne de Flandre
2016-2025
Université de Lille
2016-2025
Lille Inflammation Research International Center
2016-2025
Infinitesimal (United States)
2023
Hôpital Foch
2023
Laboratoire National de Référence
2022
Centre International de Recherche sur le Cancer
2021
ABSTRACT This document serves as an update of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) European (ESPGHAN) 2009 clinical guidelines diagnosis management gastroesophageal reflux disease (GERD) in infants children is intended to be applied daily practice a basis trials. Eight questions addressing diagnostic, therapeutic prognostic topics were formulated. A systematic literature search was performed from October 1, 2008 (if question...
Esophageal atresia (EA) is one of the most common congenital digestive anomalies. With improvements in surgical techniques and intensive care treatments, focus these patients has shifted from mortality to morbidity quality-of-life issues. These children face gastrointestinal (GI) problems not only early childhood but also through adolescence adulthood. There is, however, currently a lack systematic approach patients. The GI working group International Network on Atresia comprises members...
Feeding difficulties are frequent in children with neurological impairments and can be associated undernutrition, growth failure, micronutrients deficiencies, osteopenia, nutritional comorbidities. Gastrointestinal problems including gastroesophageal reflux disease, constipation, dysphagia also this population affect quality of life status. There is currently a lack systematic approach to the care these patients. With report, European Society Gastroenterology, Hepatology Nutrition aims...
Eosinophilic esophagitis (EoE) represents a chronic, immune/antigen-mediated esophageal disease characterized clinically by symptoms related to dysfunction and histologically eosinophil-predominant inflammation. With few exceptions, 15 eosinophils per high-power field (peak value) in ≥1 biopsy specimens are considered minimum threshold for diagnosis of EoE. The is restricted the esophagus, other causes eosinophilia should be excluded, specifically proton pump inhibitor-responsive...
<h3>Background</h3> The indications for intestinal transplantation (ITx) are still debated. Knowing survival rates and causes of death on home parenteral nutrition (HPN) will improve decisions. <h3>Methods</h3> A prospective 5-year study compared 389 non-candidates (no indication, no contraindication) 156 candidates (indication, ITx. Indications were: HPN failure (liver failure; multiple episodes catheter-related venous thrombosis or sepsis; severe dehydration), high-risk underlying disease...
An adequate vitamin D status is essential during childhood and adolescence, for its important role in cell growth, skeletal structure development. It also reduces the risk of conditions such as CVD, osteoporosis, diabetes mellitus, infections autoimmune disease. As comparable data on European level are lacking, assessment concentrations was included Healthy Lifestyle Europe by Nutrition Adolescence (HELENA) study. Fasting blood samples were obtained from a subsample 1006 adolescents (470...
Artero EG, Ruiz JR, Ortega FB, España-Romero V, Vicente-Rodríguez G, Molnar D, Gottrand F, González-Gross M, Breidenassel C, Moreno LA, Gutiérrez A; on behalf of the HELENA Study Group. Muscular and cardiorespiratory fitness are independently associated with metabolic risk in adolescents: study. Objective: To examine independent associations muscular clustered adolescents. Methods: Participants were 709 adolescents (346 boys) from 10 European centers, aged 12.5–17.5 yr, evaluated as a part...
There are limited data on the natural history of primary sclerosing cholangitis (PSC) in children. We aimed to describe disease characteristics and long‐term outcomes pediatric PSC. retrospectively collected all PSC cases from 36 participating institutions conducted a survival analysis date diagnosis dates portal hypertensive or biliary complications, cholangiocarcinoma, liver transplantation, death. analyzed patients grouped by phenotype laboratory studies at identify objective predictors...
Summary Background Although the genetic interplay with environment has a major impact on obesity development, little is known whether breastfeeding could modulate predisposition to obesity. Objectives To investigate attenuates effect of an risk score (GRS) adiposity in European adolescents. Methods Totally 751 adolescents from Healthy Lifestyle Europe by Nutrition Adolescence (HELENA) cross‐sectional study were included, divided according status into never breastfed, 1–3 months and ≥4...
<b>Aim:</b> To prospectively assess the antibacterial resistance rate in <i>Helicobacter pylori</i> strains obtained from symptomatic children Europe. <b>Methods:</b> During a 4-year period, 17 paediatric centres 14 European countries reported on patients infected with <i>H pylori</i>, for whom antibiotic susceptibility was tested. <b>Results:</b> A total of 1233 were Northern (3%), Western (70%), Eastern (9%) and Southern Europe (18%); 41% originated outside as indicated by mother's...
Abstract Objective Since inadequate food consumption patterns during adolescence are not only linked with the occurrence of obesity in youth but also subsequent risk developing diseases adulthood, establishment and maintenance a healthy diet early life is great public health importance. Therefore, aim present study was to describe evaluate well-characterized sample European adolescents against food-based dietary guidelines for first time. Design The HELENA (Healthy Lifestyle Europe by...
Evidence suggests possible synergetic effects of multiple lifestyle behaviors on health risks like obesity and other outcomes. A better insight in the clustering those behaviors, could help to identify groups who are at risk developing chronic diseases. This study examines prevalence physical activity, sedentary dietary patterns among European adolescents investigates if identified clusters be characterized by socio-demographic factors. The comprised a total 2084 (45.6% male), from eight...
This study analyzed the results of decentralized management biliary atresia (BA) in France, where an improved collaboration between centers has been promoted since 1997. Results were compared to those obtained England and Wales, BA patients have centralized three designated 1999. According their birth dates, divided into two cohorts: cohort A, with born 1986 1996, had 472 patients; B, 1997 2002, 271 patients. Survival rates calculated according Kaplan-Meier method by using log rank test Cox...
The aim of the present study was to assess food intakes and nutritional status children with allergies following an elimination diet. We conducted a cross sectional including 96 (mean age 4.7 ± 2.5 years) 95 paired controls 2.7 without allergies. Nutritional assessed using measurements weight height Z scores for weight-for-age, height-for-age weight-for-height. Nutrient assessment based on 3-day diet record. Children had weight-for-age lower than (0.1 versus 0.6 0.2 0.8 respectively). 3 or...