Claudia E. Kuehni
A5011791214- Childhood Cancer Survivors' Quality of Life
- Asthma and respiratory diseases
- Neonatal Respiratory Health Research
- Acute Lymphoblastic Leukemia research
- Cystic Fibrosis Research Advances
- Pediatric health and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory viral infections research
- Tracheal and airway disorders
- Family Support in Illness
- Adolescent and Pediatric Healthcare
- Respiratory and Cough-Related Research
- Child and Adolescent Health
- Eosinophilic Esophagitis
- Air Quality and Health Impacts
- Palliative Care and End-of-Life Issues
- Delphi Technique in Research
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Hearing, Cochlea, Tinnitus, Genetics
- Breastfeeding Practices and Influences
- Health and Medical Studies
- Inhalation and Respiratory Drug Delivery
- Cancer Risks and Factors
- Noise Effects and Management
Institute of Social and Preventive Medicine
2016-2025
University of Bern
2016-2025
University Hospital of Bern
2016-2025
University Children’s Hospital Bern
2013-2025
RELX Group (United States)
2024
University of Lucerne
2022-2023
LMU Klinikum
2023
Ludwig-Maximilians-Universität München
2023
University of Basel
2011-2023
University Children’s Hospital Basel
2013-2023
The diagnosis of primary ciliary dyskinesia is often confirmed with standard, albeit complex and expensive, tests. In many cases, however, the remains difficult despite array sophisticated diagnostic There no "gold standard" reference test. Hence, a Task Force supported by European Respiratory Society has developed this guideline to provide evidence-based recommendations on testing, especially in light new developments such tests, need for robust diagnoses patients who might enter randomised...
Primary ciliary dyskinesia (PCD) is associated with abnormal structure and function, which results in retention of mucus bacteria the respiratory tract, leading to chronic oto-sino-pulmonary disease, situs abnormalities sperm motility. The diagnosis PCD requires presence characteristic clinical phenotype either specific ultrastructural defects identified by transmission electron microscopy or evidence function. Although management children affected remains uncertain limited, it important...
Medulloblastoma is associated with rare hereditary cancer predisposition syndromes; however, consensus medulloblastoma genes have not been defined and screening guidelines for genetic counselling testing paediatric patients are available. We aimed to assess define these provide evidence future guidelines.
Primary ciliary dyskinesia (PCD) is a hereditary disorder of mucociliary clearance causing chronic upper and lower airways disease. We determined the number patients with diagnosed PCD across Europe, described age at diagnosis risk factors for late diagnosis. Centres treating children in Europe answered questionnaires provided anonymous patient lists. In total, 223 centres from 26 countries reported 1,009 aged < 20 yrs. Reported cases per million (for 5-14 yr olds) were highest Cyprus (111),...
Rationale: The current hypothesis that human pulmonary alveolarization is complete by 3 years contradicted new evidence of throughout adolescence in mammals.Objectives: We reexamined the using helium-3 (3He) magnetic resonance (MR) to assess alveolar size noninvasively between 7 and 21 years, during which lung volume nearly quadruples. If does not occur, should increase same extent.Methods: Lung volumes were measured spirometry plethysmography 109 healthy subjects aged 7–21 years. Using...
Symptoms of primary ciliary dyskinesia (PCD) are nonspecific and guidance on whom to refer for testing is limited. Diagnostic tests PCD highly specialised, requiring expensive equipment experienced scientists. This study aims develop a practical clinical diagnostic tool identify patients testing. Patients consecutively referred were studied. Information readily obtained from patient history was correlated with outcome. Using logistic regression, the predictive performance best model tested...
Abstract Background During the past 25 years, many pregnancy and birth cohorts have been established. Each cohort provides unique opportunities for examining associations of early‐life exposures with child development health. However, to fully exploit large amount available resources facilitate cross‐cohort collaboration, it is necessary accessible information on each its individual characteristics. The aim this work was provide an overview European registered in a freely database located at...
Since the publication of European Respiratory Society Task Force report in 2008, significant new evidence has become available on classification and management preschool wheezing disorders. In this report, an international consensus group reviews proposes some modifications to recommendations made 2008. Specifically, acknowledges that wheeze patterns young children vary over time with treatment, rendering distinction between episodic viral multiple-trigger unclear many patients. Inhaled...
Diagnosing asthma in children represents an important clinical challenge. There is no single gold-standard test to confirm the diagnosis. Consequently, over- and under-diagnosis of frequent children.A task force supported by European Respiratory Society has developed these evidence-based practice guidelines for diagnosis aged 5-16 years using nine Population, Intervention, Comparator Outcome (PICO) questions. The conducted systematic literature searches all PICO questions screened outputs...
Global inequalities in access to health care are reflected differences cancer survival. The CONCORD programme was designed assess worldwide and trends population-based In this study, we aimed estimate survival globally for several subtypes of childhood leukaemia. Cancer registries participating were asked submit tumour registrations all children aged 0-14 years who diagnosed with leukaemia between Jan 1, 1995, Dec 31, 2009, followed up until 2009. Haematological malignancies defined by...
Airway disease in childhood comprises a heterogeneous group of disorders. Attempts to distinguish different phenotypes have generally considered few dimensions. The present study examines wheeze and chronic cough, by fitting statistical model data representing multiple From population-based, longitudinal cohort 1,650 preschool children, 319 with parent-reported or cough were included. Phenotypes identified latent class analysis using on symptoms, skin-prick tests, lung function airway...
Post-natal exposure to air pollution is associated with diminished lung growth during school age. The current authors aimed determine whether pre-natal function changes in the newborn. In a prospective birth cohort of 241 healthy term-born neonates, tidal breathing, volume, ventilation inhomogeneity and exhaled nitric oxide (eNO) were measured unsedated sleep at age 5 weeks. Maternal particles 50% cut-off aerodynamic diameter 10 μm (PM ), nitrogen dioxide (NO 2 ) ozone (O 3 distance major...
BackgroundIt has been hypothesized that children and adolescents might be more vulnerable to possible health effects from mobile phone exposure than adults. We investigated whether use is associated with brain tumor risk among adolescents.
To evaluate the degree of psychological distress in adult childhood cancer survivors Switzerland and to characterize with significant distress.Childhood who were age younger than 16 years when diagnosed between 1976 2003, had survived more 5 years, currently 20 or older received a postal questionnaire. Psychological was assessed using Brief Symptom Inventory (BSI). Raw scores transformed into T according German norm sample, proportion participants being at increased risk for calculated (case...