Jeffrey A. Alexander

ORCID: 0000-0003-0872-7936
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About
Contact & Profiles
Research Areas
  • Eosinophilic Esophagitis
  • Eosinophilic Disorders and Syndromes
  • Esophageal and GI Pathology
  • Gastrointestinal disorders and treatments
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Gastroesophageal reflux and treatments
  • Gastrointestinal Tumor Research and Treatment
  • Esophageal Cancer Research and Treatment
  • Substance Abuse Treatment and Outcomes
  • Dysphagia Assessment and Management
  • Gastric Cancer Management and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Primary Care and Health Outcomes
  • IL-33, ST2, and ILC Pathways
  • Tracheal and airway disorders
  • Healthcare Policy and Management
  • Opioid Use Disorder Treatment
  • Abdominal vascular conditions and treatments
  • Celiac Disease Research and Management
  • Plant Virus Research Studies
  • Cytomegalovirus and herpesvirus research
  • Genetic factors in colorectal cancer
  • Foreign Body Medical Cases
  • Plant and Fungal Interactions Research
  • Patient Satisfaction in Healthcare

Mayo Clinic in Arizona
2016-2025

Mayo Clinic in Florida
2009-2025

Mayo Clinic
2014-2024

WinnMed
2014-2024

Agricultural Research Service
2022-2024

RELX Group (Netherlands)
2019-2024

University of Nebraska–Lincoln
2022-2023

United States Department of Agriculture
2023

University of Minnesota Rochester
2006-2022

University of Maryland Center for Environmental Science
2014

Evan S. Dellon Nirmala Gonsalves J. Pablo Abonia Jeffrey A. Alexander Nicoleta C. Arva and 86 more Dan Atkins Stephen Attwood Marcus Auth Dominique D. Bailey Luc Biederman Carine Blanchard Peter A Bonis Paroma Bose Albert J. Bredenoord Joy W. Chang Mirna Chehade Margaret H. Collins Carlo Di Lorenzo Jorge Amil Dias Ranjan Dohil Christophe Dupont Gary W. Falk Cristina Targa Ferreira Adam Fox Robert M. Genta Thomas Greuter Sandeep K. Gupta Ikuo Hirano Girish Hiremath Jennifer L. Horsley‐Silva Shunji Ishihara Norihisa Ishimura Elizabeth T. Jensen Carolina Gutiérrez‐Junquera David A. Katzka Paneez Khoury Yoshikazu Kinoshita Kara Kliewer Sibylle Koletzko John Leung Chris A. Liacouras Alfredo J. Lucendo Lisa J. Martin Emily C. McGowan Calies Menard‐Katcher David C. Metz Talya L. Miller Fouad J. Moawad Amanda B. Muir Vincent A. Mukkada Simon Murch Quan M. Nhu Ichiro Nomura Samuel Nurko Yoshikazu Ohtsuka Salvatore Oliva Rok Orel Alexandra Papadopoulou Dhyanesh A. Patel Robert D. Pesek Kathryn A. Peterson Hamish Philpott Philip E. Putnam Joel E. Richter Rachel Rosen Melanie A. Ruffner Ekaterina Safroneeva Philipp Schreiner Alain Schoepfer Shauna Schroeder Neil Shah Rhonda F. Souza Stuart J. Spechler Jonathan M. Spergel Alex Straumann Nicholas J. Talley Nikhil Thapar Yvan Vandenplas Rajitha D. Venkatesh Mário C. Vieira Ulrike von Arnim Marjorie M. Walker Joshua B. Wechsler Barry K. Wershil Benjamin L. Wright Y. Yamada Guang‐Yu Yang Noam Zevit Marc E. Rothenberg Glenn T. Furuta Seema S. Aceves

10.1016/j.cgh.2022.02.017 article EN Clinical Gastroenterology and Hepatology 2022-02-16

This study tested whether leadership instability--a systemic pattern of frequent succession in the top management position an organization--was associated with sociopolitical structures that define relationship between board and chief executive officer (CEO), controlling for temporal patterns organizational life-cycle stage. In organizations are not profit maximizing subject to considerable uncertainty, such governance properties were hypothesized affect instability independent growth or...

10.2307/2393255 article EN Administrative Science Quarterly 1993-03-01

To compare the performance of multiphase computed tomographic (CT) enterography with that capsule endoscopy in a group patients obscure gastrointestinal bleeding (OGIB).This prospective HIPAA-compliant study was approved by institutional review board and conflict interest committee. All provided written informed consent. Two radiologists, blinded to clinical data results endoscopy, interpreted images from CT independently, discordant interpretations resolved consensus. Results were compared...

10.1148/radiol.11110143 article EN Radiology 2011-06-04

This retrospective HIPAA-compliant study was approved by the institutional review board and conflict of interest committee. Patients gave informed consent for use medical records. The purpose to retrospectively evaluate findings depicted at computed tomographic (CT) enterography performed with a 64-section CT system using neutral enteric contrast material three-phase acquisition in patients obscure gastrointestinal bleeding (OGIB). Twenty-two outpatients (11 men, 11 women; age range, 37-83...

10.1148/radiol.2462061920 article EN Radiology 2008-01-29

Estimation of the prevalence oesophageal narrowing and its clinical relevance in patients with eosinophilia is probably underestimated by endoscopy.To determine sensitivity specificity oesophagogastroduodenoscopy (EGD) for when compared to a structured oesophagram.We conducted retrospective chart review at Mayo Clinic, Rochester adult eosinophilic infiltration >15 eosinophils/hpf symptomatic dysphagia, who underwent barium oesophagram. The EGD were evaluated against gold standard Demographic...

10.1111/apt.12977 article EN Alimentary Pharmacology & Therapeutics 2014-10-07

Objectives: Management of eosinophilic esophagitis (EoE) requires repeated endoscopic mucosal sampling to assess disease activity. A less invasive and expensive means monitoring EoE is required. The objective this study was the accuracy, safety, tolerability cytosponge compared endoscopy biopsy for histologic assessment EoE. Methods: In prospective two-center cross-sectional study, patients with known underwent followed by biopsy. Sample adequacy eosinophil counts (eos/HPF) were determined...

10.1038/ajg.2017.244 article EN The American Journal of Gastroenterology 2017-08-15

End points used to determine treatment efficacy in eosinophilic esophagitis (EoE) have evolved over time. With multiple novel therapies development for EoE, harmonization of outcomes measures will facilitate evidence synthesis and appraisal when comparing different treatments. We sought develop a core outcome set (COS) controlled observational studies pharmacologic diet interventions adult pediatric patients with EoE. Candidate were generated from systematic literature reviews patient...

10.1016/j.jaci.2021.07.001 article EN cc-by Journal of Allergy and Clinical Immunology 2021-07-06

Celiac disease (CD) is characterized by small intestinal inflammation and mucosal atrophy. Endoscopic markers of villous atrophy are reported to be present in 88-100% untreated celiac patients. In patients being evaluated for iron deficiency anemia (IDA), we examined whether endoscopic could predict histological results consistent with CD.One hundred thirteen without histories CD had bowel biopsies evaluate IDA using videoendoscopy. Markers suggesting were noted at endoscopy. Biopsy...

10.1111/j.1572-0241.2002.05612.x article EN The American Journal of Gastroenterology 2002-04-01

Eosinophilic esophagitis (EoE) is characterized by infiltration of eosinophils into esophageal epithelium. Blood levels an eosinophil granule protein, eosinophil-derived neurotoxin (EDN), have been proposed as a biomarker for EoE. However, information regarding localization EDN in the diseased tissues has not available. The goal this study was to evaluate magnitude and distribution deposition tissue specimens from esophagus EoE patients.

10.1038/ajg.2009.584 article EN The American Journal of Gastroenterology 2009-11-03

Aliment Pharmacol Ther 2012; 35: #–# Summary Background The consensus statements for eosinophilic oesophagitis recommend that ambulatory pH monitoring is one means of determining if gastro‐oesophageal reflux the cause oesophageal eosinophilia and should guide pharmacological therapy. Aim To evaluate prospectively accuracy as a predictor endoscopic, histological symptomatic response in patients with eosinophilia. Methods We conducted prospective trial which infiltration ≥15 eos/hpf underwent...

10.1111/j.1365-2036.2011.04922.x article EN Alimentary Pharmacology & Therapeutics 2011-11-24
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