A5066040432- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Allergic Rhinitis and Sensitization
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inhalation and Respiratory Drug Delivery
- Neuroscience of respiration and sleep
- Food Allergy and Anaphylaxis Research
- Obstructive Sleep Apnea Research
- Pediatric health and respiratory diseases
- Neonatal Respiratory Health Research
- Dermatology and Skin Diseases
- Respiratory Support and Mechanisms
- Tracheal and airway disorders
- Eosinophilic Esophagitis
- Obesity, Physical Activity, Diet
- Cystic Fibrosis Research Advances
- Child Nutrition and Feeding Issues
- Contact Dermatitis and Allergies
- Occupational exposure and asthma
- Child and Adolescent Health
- Vitamin D Research Studies
- Infant Development and Preterm Care
- Pharmaceutical studies and practices
- Respiratory viral infections research
- Infant Health and Development
University of Verona
2016-2025
University of Insubria
2023
Azienda Ospedaliera Universitaria Integrata Verona
2004-2022
Nuovo Ospedale San Giovanni di Dio
2021-2022
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo
2021
Cineca
2021
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2007-2019
University of Milan
1982-2019
University Orthopedics Center
2017
New York University
2014
The aim of this study was to test the hypothesis that youths with obesity, when removed from structured school activities and confined their homes during coronavirus disease 2019 pandemic, will display unfavorable trends in lifestyle behaviors.The sample included 41 children adolescents obesity participating a longitudinal observational located Verona, Italy. Lifestyle information including diet, activity, sleep behaviors collected at baseline 3 weeks into national lockdown which home...
Diagnosing asthma in children represents an important clinical challenge. There is no single gold-standard test to confirm the diagnosis. Consequently, over- and under-diagnosis of frequent children.A task force supported by European Respiratory Society has developed these evidence-based practice guidelines for diagnosis aged 5-16 years using nine Population, Intervention, Comparator Outcome (PICO) questions. The conducted systematic literature searches all PICO questions screened outputs...
Measurement of fractional exhaled nitric oxide in air is an exciting innovative technique that gives new insights to the pathophysiology lung disease and asthma particular, with many potential clinical applications. Careful standardisation measurement techniques will facilitate use this paediatric respiratory medicine: Task Force was set up for purpose. Methodologies, all age groups, are already available there abundant questions relating interpretation application waiting be addressed....
Vitamin D deficiency could be associated with the prevalence of atopic dermatitis (AD).We carried out a study to see whether deficient/insufficient levels vitamin correlate severity skin disease.Using SCORAD index, we evaluated disease in 37 children (17 girls and 20 boys) aged between 8 months 12 years AD, consecutively enrolled study. Serum 25-hydroxyvitamin [25(OH)D] were determined by chemiluminescent method. Specific IgE (sIgE) Staphylococcus aureus enterotoxins sIgE Malassezia furfur...
Oxidative stress is implicated in the pathogenesis of asthma, and clinical studies show an imbalance level oxidants to antioxidants subjects with asthma. Aldehydes glutathione are examples biomarkers oxidant-induced damage antioxidant status respectively. In study, we applied analytical techniques based on liquid chromatography for assessment aldehydes exhaled breath condensate children asthma control without Twelve were evaluated at exacerbation after 5 days therapy prednisone. At...
Recurrent respiratory infections (RRIs) are a common clinical condition in children, fact about 25% of children under 1 year and 6% during the first 6 years life have RRIs. In most cases, occur with mild manifestations frequency episodes tends to decrease over time complete resolution by 12 age. However, RRIs significantly reduce child family quality lead significant medical social costs.Despite importance this condition, there is currently no agreed definition term literature, especially...
Exhaled nitric oxide and eosinophil sputum markers are considered noninvasive ways in which to evaluate airway inflammation asthma. The aim of this study was the relationships between these methods evaluation asthmatic children. In a cross-sectional 25 mild-moderate children (aged 6-13 yrs, 10 patients on inhaled steroids) exhaled NO measured along with induced by inhalation hypertonic saline solution. processed for count cationic protein (ECP) determination. Serum ECP lung function (forced...
Macrolide antibiotics have immunomodulatory effects that may be beneficial to patients with chronic inflammatory pulmonary conditions. The aim of this study was evaluate the azithromycin on lung function, bronchial hyperresponsiveness (BHR), and airway inflammation in asthmatic children. Sixteen children were treated either or placebo for 8 weeks. Lung BHR expressed as dose-response slope (DRS) forced expiratory volume 1 second (FEV1) fall after hypertonic saline inhalation (DRS), induced...
Epidemiological studies have established a relationship between low levels of serum vitamin D and reduced lung function in healthy adults, asthma onset severity children. However, no study has examined the exercise-induced bronchoconstriction asthmatic We evaluated 25-hydroxyvitamin concentrations baseline forced vital capacity (FVC), expiratory volume 1 s (FEV1) change FEV1 (ΔFEV1) after standardised exercise challenge 45 children with intermittent asthma. Only 11% had desirable (at least...
Background Atopic dermatitis (AD) is a common condition in infancy which usually disappears by 3 years of age significant proportion children. The prognosis mostly determined severity and presence atopic sensitization. Objectives To investigate prevalence AD, comorbidities risk factors population preschool children aged 3–5 years. Methods Children kindergartens were evaluated. International Study Asthma Allergies Childhood written questionnaire (WQ) was used, with additional questions on...
Asthma prevalence in Italy is on the rise and estimated to be over 6% of general population. The diagnosis asthma can challenging elusive, especially children last two decades has brought evidences that not a single disease but consists various phenotypes. Symptoms underestimated by patient or underreported clinician physical signs scanty. Usual objective measures, like spirometry, are necessary sometimes significant. Despite proper treatment, very severe condition (even leading death),...
Currently available European Alpine Altitude Climate Treatment (AACT) programs combine the physical characteristics of altitude with avoidance environmental triggers in alpine climate and a personalized multidisciplinary pulmonary rehabilitation approach. The reduced barometric pressure, oxygen air density, relatively low temperature humidity, increased UV radiation at moderate induce several physiological immunological adaptation responses. include aeroallergens such as house dust mites...
Introduction Dupilumab, a monoclonal antibody targeting the IL-4 receptor alpha subunit, effectively blocks both and IL-13 mediated pathways. Its introduction has represented significant advancement in treatment of severe asthma other Type 2 (T2) conditions, including nasal polyps, atopic dermatitis, eosinophilic esophagitis. To date, Dupilumab demonstrated optimal efficacy safety profile.
Summary Background The aim of our study was to assess the prevalence rhinitis, sneezing, runny or blocked nose apart from colds in a pre‐school children population and evaluate risk factors relationship with allergic diseases sensitization. Methods Eighteen nursery schools were randomly selected. International Study Asthma Allergies Childhood (ISAAC) written questionnaire (WQ) distributed filled by parents (3–5 years). sensitization common aeroallergens foods evaluated skin prick test (SPT)....
Summary A cohort of 12 asthmatic children was followed over several months, during which they moved back and forth from an allergen‐free to allergen‐rich environment at high low altitude, respectively. The were treated with non‐steroidal anti‐asthmatic drugs as clinically needed. Histamine PC20‐FEV 1 unaltered the study period, whereas serum levels eosinophil cationic protein (ECP) X (EPX) showed significant changes when exposed offending allergens. total IgE significantly increased...