A5032185441- Bone health and osteoporosis research
- Hip and Femur Fractures
- Bone health and treatments
- Bone fractures and treatments
- Bone and Joint Diseases
- Long-Term Effects of COVID-19
- Orthopedic Surgery and Rehabilitation
- Rheumatoid Arthritis Research and Therapies
- COVID-19 Clinical Research Studies
- Hip disorders and treatments
- Health Systems, Economic Evaluations, Quality of Life
- Medical Imaging Techniques and Applications
- Diabetes Treatment and Management
- Orthopaedic implants and arthroplasty
- Vitamin D Research Studies
- Advanced X-ray and CT Imaging
- COVID-19 and healthcare impacts
- Pelvic and Acetabular Injuries
- Radiomics and Machine Learning in Medical Imaging
- Bone Metabolism and Diseases
- Medical Imaging and Analysis
- Chronic Disease Management Strategies
- Parathyroid Disorders and Treatments
- Nutrition and Health in Aging
- Chronic Obstructive Pulmonary Disease (COPD) Research
Maastricht University Medical Centre
2016-2025
VieCuri Medisch Centrum
2016-2025
Maastricht University
2016-2025
University Medical Center
2010-2024
Hasselt University
2014-2023
Geneeskundige en Gezondheidsdienst
2011-2023
The University of Melbourne
2020
Amsterdam University Medical Centers
2020
Cancer Center Amsterdam
2020
Center for Rheumatology
2016-2020
Background: A fracture liaison service model of care is widely recommended and applied, but data on its effectiveness are scarce. Therefore, the risk subsequent nonvertebral fractures mortality within two years after a was analyzed in patients who presented to hospital with without service. Methods: In 2005 2006, all consecutive an age fifty or older presenting were included. group that (the no-FLS group), only standard procedures followed address proper fracture-healing. FLS dual x-ray...
KCNJ11 mutations cause permanent neonatal diabetes through pancreatic ATP-sensitive potassium channel activation. 90% of patients successfully transfer from insulin to oral sulfonylureas with excellent initial glycaemic control; however, whether this control is maintained in the long term unclear. Sulfonylurea failure seen about 44% people type 2 after 5 years treatment. Therefore, we did a 10-year multicentre follow-up study large international cohort address key questions relating...
Previously undetected contributors to secondary osteoporosis and metabolic bone diseases (SECOB) are frequently found in patients with osteoporosis, but the prevalence at time they present a clinical fracture is unknown.All consecutive recent vertebral or nonvertebral fracture, who were able willing be investigated (n = 626: 482 women, 144 men, age range 50-97 yr) had mineral density laboratory investigations (serum calcium, inorganic phosphate, 25-hydroxyvitamin D, creatinine, intact PTH,...
The World Health Organization fracture risk assessment tool (FRAX) and the Garvan calculator are both widely available tools for individualized prediction in daily practice. FRAX model is implemented several guidelines most used at present. However, clinicians should take into account differences between models, especially with regard to effect of number falls, clustering previous fractures, clinical factors on outcome predicted risk. Further development will be needed optimal integration...
Little is known about long-term excess mortality following fragility nonhip fractures. The study aimed to determine which fracture was associated with and for how long the postfracture persisted. This nationwide registry-based follow-up included all individuals in Denmark aged 50+ years who first experienced fractures 2001 were followed up 10 their risk. contribution of at precise time intervals examined using relative survival analysis, accounting time-related changes background population....
Objective Osteoporotic fragility fractures, that are common in men and women, signal increased risk of future fractures premature mortality. Less than one-third postmenopausal women fewer prescribed active treatments to reduce fracture risk. Therefore, this study the association oral bisphosphonate recommendation with subsequent mortality over eight years a liaison service setting was analysed. Materials methods In prospective cohort study, 5011 aged >50 years, who sustained clinical...
Data on long-term consequences of non-hip non-vertebral (NHNV) fractures, accounting for approximately two-thirds all fragility are scanty. Our study aimed to quantify the population-wide impact NHNV fractures mortality. The national population-based prospective cohort (Canadian Multicentre Osteoporosis Study) included 5526 community dwelling women and 2163 men aged 50 years or older followed from July 1995 September 2013. Population number was used average people whom one death would be...
Abstract Type 2 diabetes mellitus (T2DM) is associated with greater risk for colorectal cancer (CRC). The age of onset T2DM decreasing worldwide. An increased CRC in young patients could be relevant the at which to initiate screening. We report on attention diagnosis. used pharmacy data (from 1998 2010) from PHARMO Database Network linked Eindhoven Cancer Registry. Multivariable time-dependent Cox regression analyses were conducted calculate hazard ratios (HR) developing comparing non-T2DM....
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a new class of drugs that might have potential beneficial effect on bone metabolism. Data the GLP-1 RAs and fracture risk lacking. The aim present study was to investigate association between use fracture. A case-control performed using Danish National Health Service data. Cases were those who sustained controls without during period (2007-2011), all aged 18 years above. Conditional logistic regression estimated odds ratios (OR) with...