A5060059683- Obesity, Physical Activity, Diet
- Blood Pressure and Hypertension Studies
- Birth, Development, and Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Chronic Kidney Disease and Diabetes
- Health Promotion and Cardiovascular Prevention
- Nutritional Studies and Diet
- Dialysis and Renal Disease Management
- Atrial Fibrillation Management and Outcomes
- Sodium Intake and Health
- Lipoproteins and Cardiovascular Health
- Cardiovascular Health and Risk Factors
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Chronic Disease Management Strategies
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Occupational Health and Safety Research
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Disease Prevention
- Heart Failure Treatment and Management
- Workplace Health and Well-being
- Diet, Metabolism, and Disease
- Cardiac Imaging and Diagnostics
- Diet and metabolism studies
- Diabetes Management and Education
Dokkyo Medical University
2016-2025
University of Tsukuba
2011-2025
Health Services Research & Development
2021-2025
Ibaraki Womens Junior College
2004-2021
Dokkyo University
2009-2014
Ibaraki Prefectural Police
2011-2013
Osaka University
2013
American Public Health Association
2011
Ibaraki Prefectural Central Hospital
2009
Ibaraki Prefectural University of Health Sciences
2009
Most studies that have evaluated the association between body-mass index (BMI) and risks of death from any cause specific causes been conducted in populations European origin.We performed pooled analyses to evaluate BMI risk among more than 1.1 million persons recruited 19 cohorts Asia. The included approximately 120,700 deaths occurred during a mean follow-up period 9.2 years. Cox regression models were used adjust for confounding factors.In East Asians, including Chinese, Japanese,...
Background The occurrence of diabetes has greatly increased in low- and middle-income countries, particularly Asia, as the prevalence overweight obesity; European-derived populations, obesity are established causes diabetes. shape association with risk its overall impact have not been adequately studied Asia. Methods Findings A pooled cross-sectional analysis was conducted to evaluate between baseline body mass index (BMI, measured weight kg divided by square height m) self-reported status...
<h3>Importance</h3> Early identification of individuals at elevated risk developing chronic kidney disease (CKD) could improve clinical care through enhanced surveillance and better management underlying health conditions. <h3>Objective</h3> To develop assessment tools to identify increased CKD, defined by reduced estimated glomerular filtration rate (eGFR). <h3>Design, Setting, Participants</h3> Individual-level data analysis 34 multinational cohorts from the CKD Prognosis Consortium...
Background— Few studies have examined the association between low levels of low-density lipoprotein (LDL) cholesterol and risk intraparenchymal hemorrhage. Methods Results— A total 30 802 men 60 417 women, 40 to 79 years age with no history stroke or coronary heart disease, completed a baseline factor survey in 1993 under auspices Ibaraki Prefectural Health Study. Systematic mortality surveillance was performed through 2003, 264 hemorrhage deaths were identified. LDL calculated Friedewald...
Background Tobacco smoking is a major risk factor for many diseases. We sought to quantify the burden of tobacco-smoking-related deaths in Asia, parts which men's prevalence among world's highest. Methods and Findings performed pooled analyses data from 1,049,929 participants 21 cohorts Asia risks total cause-specific mortality associated with tobacco using adjusted hazard ratios their 95% confidence intervals. then estimated smoking-related adults aged ≥45 y 2004 Bangladesh, India, mainland...
The age of adiposity rebound (AR) is defined as the time at which BMI starts to rise after infancy and thought be a marker later obesity. To determine whether this related future occurrence metabolic syndrome, we investigated relationship timing AR with consequences 12 years age.A total 271 children (147 boys 124 girls) born in 1995 1996 were enrolled study. Serial measurements conducted ages 4 8 months 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, years, based on was calculated. Plasma lipids...
<h3>Importance</h3> Asia is home to the largest diabetic populations in world. However, limited studies have quantified association of diabetes with all-cause and cause-specific mortality Asian populations. <h3>Objectives</h3> To evaluate investigate potential effect modifications diabetes-mortality associations by participants’ age, sex, education level, body mass index, smoking status. <h3>Design, Setting, Participants</h3> This pooled analysis incorporated individual participant data from...
Chronic kidney disease (CKD) measures (estimated glomerular filtration rate [eGFR] and albuminuria) are frequently assessed in clinical practice improve the prediction of incident cardiovascular (CVD), yet most major guidelines do not have a standardized approach for incorporating these into CVD risk prediction. "CKD Patch" is validated method to calibrate predicted from established equations according CKD measures.Utilizing data 4,143,535 adults 35 datasets, we developed several Patches"...
Neonicotinoid insecticides are widely used systemic pesticides with nicotinic acetylcholine receptor agonist activity that a concern as environmental pollutants. Neonicotinoids in humans and the environment have been reported, but few studies examined their presence fetuses newborns. The objective of this study is to determine exposure neonicotinoids metabolites very low birth weight (VLBW) infants.An analytical method for seven one neonicotinoid metabolite, N-desmethylacetamiprid (DMAP),...
Abstract Aims The 2021 European Society of Cardiology (ESC) guideline on cardiovascular disease (CVD) prevention categorizes moderate and severe chronic kidney (CKD) as high very-high CVD risk status regardless other factors like age does not include estimated glomerular filtration rate (eGFR) albuminuria in its algorithms, systemic coronary estimation 2 (SCORE2) older persons (SCORE2-OP), to predict risk. We developed validated an ‘Add-on’ incorporate CKD measures into these using a...
Background— It is unclear whether mild hypertensive retinopathy a risk factor for mortality. This study examined could be cardiovascular mortality in subjects with and without hypertension. Methods Results— In this cohort study, 87 890 individuals (29 917 men 57 973 women) 40 to 79 years of age 1993 were followed up until 2008. Retinal photography was classified as normal, grade 1, or 2 based on the Keith-Wagener-Barker system. Risk ratios all-cause cause-specific each classification...
For examination of sex- and age-specific relations between smoking risk type 2 diabetes mellitus, 39,528 nondiabetic men 88,613 women aged 40-79 years who underwent health checkups in Ibaraki-ken, Japan, 1993 were followed through 2002. Risk ratios for according to habits calculated using a Cox proportional hazards model. Compared with never smokers, the ratio among current after adjustment age, systolic blood pressure, antihypertensive mediation use, alcohol intake, parental history...
Purpose: To examine the relationship between body mass index (BMI) and risk of stage ≥3 chronic kidney disease (CKD) in a general Japanese population.Methods: A total 105 611 participants aged 40–79 years who completed health checkups Ibaraki Prefecture, Japan, were free CKD 1993 followed-up through 2006. Stage was defined by an estimated glomerular filtration rate <60 mL/min/1.73 m2 reported during at least 2 successive annual surveys or as treatment for disease. Hazard ratios (HRs)...
There are limited studies addressing whether proteinuria and estimated glomerular filtration rate (eGFR) independently associated with cardiovascular disease in Asia. Using data from 7 prospective cohorts recruited between 1980 1994 Japan, we assessed the influence of (≥1+ on dipstick) reduced eGFR risk mortality 39,405 participants (40–89 years) without kidney failure. During a 10.1-year follow-up, 1,927 subjects died disease. Proteinuria was 1.75-fold (95% confidence interval (CI): 1.44,...
AimsThe long-term prognosis of subjects with supraventricular premature complexes (SVPCs) remains unclear in the general population. The aim this study was to examine prognostic significance SVPCs community-based health checkups.
Background The proportion of Japanese workers experiencing intense worry or stress during working life is in excess 60%, and the incidence psychiatric disorders suicide due to psychological burden from work duties increasing. To confirm whether response measured by Brief Job Stress Questionnaire (BJSQ) can identify risk for depression, a cohort study was conducted evaluate BJSQ associated with onset depression. Methods A total 1,810 participants aged 20–70 years 2005 completed were...
Background Aortic aneurysm rupture and acute aortic dissection are life-threatening conditions represent an ever-growing public health challenge. Comprehensive epidemiologic investigations for their risk factors scant. We aimed to investigate associated with mortality from diseases through analysis of a community-based Japanese cohort. Methods Results IPHS (Ibaraki Prefectural Health Study) comprises 95 723 participants who took part in municipal checkups 1993. Factors considered included...