A5006558823- Nutritional Studies and Diet
- Blood Pressure and Hypertension Studies
- Sodium Intake and Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Health and Disease Prevention
- Cardiovascular Health and Risk Factors
- Cardiovascular Disease and Adiposity
- Obesity, Physical Activity, Diet
- Liver Disease Diagnosis and Treatment
- Lipoproteins and Cardiovascular Health
- Alcohol Consumption and Health Effects
- Diet and metabolism studies
- Acute Ischemic Stroke Management
- Fatty Acid Research and Health
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Heart Rate Variability and Autonomic Control
- Cancer, Lipids, and Metabolism
- Nutrition and Health in Aging
- Health Promotion and Cardiovascular Prevention
- Smoking Behavior and Cessation
- Health disparities and outcomes
- Climate Change and Health Impacts
- Adipokines, Inflammation, and Metabolic Diseases
Shiga University of Medical Science
2016-2025
Shiga University
2015-2024
University of Pittsburgh
2000-2022
Okayama University
2022
Suzuki (Japan)
2019
Northwestern University
2000-2018
Imperial College London
2004-2018
Fu Wai Hospital
2004-2018
Chinese Academy of Medical Sciences & Peking Union Medical College
2004-2018
University of Illinois Chicago
2018
In this prospective, randomized, open-label, blinded end point study, we aimed to establish whether strict blood pressure control (<140 mm Hg) is superior moderate (≥140 Hg <150 in reducing cardiovascular mortality and morbidity elderly patients with isolated systolic hypertension. We divided 3260 aged 70 84 years hypertension (sitting 160 199 into 2 groups, according or treatment. A composite of events was evaluated for ≥2 years. The (1545 patients) (1534 groups were well matched...
Large-scale population phenotyping for molecular epidemiological studies is subject to all the usual criteria of analytical chemistry. As part a major investigation we have used high-resolution 1H NMR spectroscopy characterize 24-h urine specimens obtained from samples in Aito Town, Japan (n = 259), Chicago, IL 315), and Guangxi, China 278). We investigated reproducibility, specimen storage procedures, interinstrument variability, split detection. Our data show that multivariate...
High intakes of dietary sodium are associated with elevated blood pressure levels and an increased risk cardiovascular disease. National international guidelines recommend reduced intake in the general population, which necessitates population-wide surveillance. We assessed utility casual (spot) urine specimens estimating 24-hour urinary excretion as a marker International Cooperative Study on Salt, Other Factors, Blood Pressure. There were 5,693 participants recruited 1984–1987 at ages...
In a large-scale population-based metabolic phenotyping study, diverse sets of urinary metabolites, including gut microbial co-metabolites, were reproducibly associated with human adiposity.
<h3>Abstract</h3> <b>Objectives</b> : To assess the relation between alcohol intake and blood pressure in men women at younger older ages; to examine influence of amount pattern consumption, as well acute effects, taking into account body mass index, smoking, urinary sodium potassium excretion. Design - Subjects reported consumption20for each seven days before standardised measurement, whether they had consumed any 24 hours measurement. <b>Setting</b> 50 centres worldwide. <b>Subjects</b>...
OBJECTIVE—To provide reliable age- and region-specific estimates of the associations between diabetes major cardiovascular diseases death in populations from Asia-Pacific region. RESEARCH DESIGN AND METHODS—Twenty-four cohort studies Asia, Australia, New Zealand (median follow-up, 5.4 years) provided individual participant data 161,214 people (58% Asia) whom 4,873 had a history at baseline. The with risks coronary heart disease, stroke, cause-specific mortality during follow-up were...
Epidemiological studies have shown that the incidence of coronary artery disease increases as LDL- C, TC1-9), and TG10, 11) levels rise HDL-C level lowers5, 8, 12) both in Japan Western countries (Fig.1). At present, prevalence is much lower than countries13-16). However, recent LDL-C TC Japanese associated with so-called Westernization diet implies future disease. In this guideline, therefore, criteria for diagnosis dyslipidemia were defined Table 1, a greater emphasis on prevention...
Findings from short-term randomized trials indicate that dietary supplements of omega-3 polyunsaturated fatty acids (PFA) lower blood pressure hypertensive persons, but effect size in nonhypertensive individuals is small and nonsignificant. Data are lacking on food PFA general populations. The International Study Macro- Micro-nutrients Blood Pressure (INTERMAP) an international cross-sectional epidemiologic study 4680 men women ages 40 to 59 17 population-based samples China, Japan, United...
The obesity epidemic has focused attention on relationships of sugars and sugar-sweetened beverages (SSBs) to cardiovascular risk factors. Here we report cross-sectional associations SSBs, diet beverages, with blood pressure (BP) for United Kingdom US participants the International Study Macro/Micronutrients Blood Pressure. Data collected include four 24-hour dietary recalls, two urine collections, 8 BP readings, questionnaire data 2696 people ages 40 59 years age from 10 US/United...
Objective About half of the world's burden cardiovascular disease is carried by countries in Asia-Pacific region. This study aimed to quantify contribution hypertension diseases (CVD) at country level, calculating sex-specific, population-attributable fractions (PAFs) for fatal ischaemic heart (IHD) and stroke (haemorrhagic ischaemic) World Health Organization Western Pacific South-east Asian regions. Methods The most recent sex-specific prevalence data on were sought. Age-adjusted hazard...