A5062427393- Nutritional Studies and Diet
- Diet and metabolism studies
- Sodium Intake and Health
- Consumer Attitudes and Food Labeling
- Estrogen and related hormone effects
- Nutrition, Genetics, and Disease
- Obesity, Physical Activity, Diet
- Breast Cancer Treatment Studies
- Cancer Risks and Factors
- Dental Health and Care Utilization
- Cancer, Lipids, and Metabolism
- Nutrition and Health in Aging
- Dental Education, Practice, Research
- Dental Research and COVID-19
- Oral microbiology and periodontitis research
- Inflammatory mediators and NSAID effects
- Child Nutrition and Water Access
- Lung Cancer Treatments and Mutations
- Food Safety and Hygiene
- Birth, Development, and Health
- Hemoglobinopathies and Related Disorders
- Cancer Cells and Metastasis
- Advanced Radiotherapy Techniques
- Genetic factors in colorectal cancer
- Mosquito-borne diseases and control
University of Westminster
2011-2025
King's College London
2005-2021
Alberta Hospital Edmonton
2019
University Hospitals Birmingham NHS Foundation Trust
2019
Quadram Institute
2019
Public Health England
2017-2019
Norfolk and Norwich University Hospitals NHS Foundation Trust
2019
St Martins Hospital
2017
Heartlands Hospital
2015
Imperial College London
2003-2014
BACKGROUND: Axillary lymph node dissection is an established component of the surgical treatment breast cancer, and important procedure in cancer staging; however, it associated with unpleasant side effects. We have investigated a radioactive tracer-guided that facilitates identification, removal, pathologic examination sentinel (i.e., first receiving lymphatic fluid from area containing tumor) to predict status axilla assess safety foregoing axillary if shows no involvement. METHODS:...
Background: Tamoxifen reduces the risk of breast cancer in women at high for disease but increases endometrial tumors and venous thromboembolisms, possibly a dose-dependent fashion. We compared effects tamoxifen 1 mg/day 5 with those standard dose 20 on proliferation using surrogate endpoint marker (Ki-67 expression) blood biomarkers associated cancer, cardiovascular disease, bone fracture risk. Methods: randomly assigned 120 estrogen receptor (ER)-positive to 1, 5, or 4 weeks. Expression...
The obesity epidemic has focused attention on relationships of sugars and sugar-sweetened beverages (SSBs) to cardiovascular risk factors. Here we report cross-sectional associations SSBs, diet beverages, with blood pressure (BP) for United Kingdom US participants the International Study Macro/Micronutrients Blood Pressure. Data collected include four 24-hour dietary recalls, two urine collections, 8 BP readings, questionnaire data 2696 people ages 40 59 years age from 10 US/United...
Objective To compare rates of necrotising enterocolitis (NEC), late-onset sepsis, and mortality in 5-year epochs before after implementation routine daily multistrain probiotics administration high-risk neonates. Design Single-centre retrospective observational study over the 10-year period from 1 January 2008 to 31 December 2017. Setting Level 3 neonatal intensive care unit (NICU) Norfolk Norwich University Hospital, UK. Patients Preterm neonates at high risk NEC: admitted NICU within days...
Findings from observational and interventional studies on the relationship of dietary linoleic acid, main polyunsaturated fatty with blood pressure have been inconsistent. The International Study Macro-Micronutrients Blood Pressure is an international cross-sectional epidemiological study 4680 men women ages 40 to 59 years 17 population samples in China, Japan, United Kingdom, States. We report associations acid intake individuals their pressure. Nutrient data were based 4 in-depth multipass...
Abstract Background We prospectively examined the prevalence, co‐existence, and change of geriatric giant syndromes in older people over 2 years. Methods Two hundred five subjects were before after Ten giants assessed at both time points: cognitive impairment, depression, orthostatic hypotension, polypharmacy, sarcopenia, dynapenia, falls, chronic pain, faecal urinary incontinence. Results Chronic incontinence three most commonly occurring baseline (57%, 46%, 40%). The presence incontinence,...
McCance and DrWiddowson in the 1930's have been extensively developed, this work composes a valuable reference tool for all those with an interest UK food
Objective: In short-term feeding trials, replacement of other macronutrients with monounsaturated fatty acid reduces blood pressure. However, observational studies have not clearly demonstrated a relationship between intake and We report associations individuals pressure in cross-sectional study. Methods: The International Study Macro/Micronutrients Blood Pressure is epidemiologic study 4680 men women ages 40–59 years from 17 population samples China, Japan, UK USA. Nutrient data were based...
Changes in the design of hospital wards have usually been determined by architects and members nursing medical professions, views preferences patients seldom sought directly The Hospital Anxiety Depression scale Disturbance Due to Noise questionnaire were administered 64 female on bay Nightingale together with a designed for this study Perceptions social physical factors ward examined, their relationship psychological well‐being sleep patterns results show that seemed offer more favourable...
The present paper describes the systematic development of an FFQ to assess intake fatty acids and antioxidants in school-aged children. In addition, a validation study applying 24 h dietary recalls was performed.Using variance-based Max_r method, list eighty-two foods compiled from data obtained by 3 d weighed records. were used design FFQ, comprehensibility which evaluated feasibility study. validated subset 101 children German Infant Nutritional Intervention Study (GINI PLUS) against one...
A glycoproteomic study has previously shown cadherin-5 (CDH5) to be a serological marker of metastatic breast cancer when both protein levels and glycosylation status were assessed. In this we aimed further validate the utility CDH5 as biomarker for progression. nested case–control serum samples from patients, which n=52 had developed distant recurrence within 5 years post-diagnosis n=60 remained recurrence-free. ELISAs used quantify patient assess by Helix pomatia agglutinin (HPA) binding....
Background: Tobacco is addictive and cigarette smoking causes significant morbidity among smokers due to the harmful side effects of tar other constituents. Many diseases caused by tobacco result in death, which half are premature. When stop smoking, even middle age, there a substantial improvement life expectancy. Stopping not always so easy: nature nicotine makes it lot easier start than permanently. Currently, 40% men 30% women European Union smoke, although little information about how...
Information on dietary supplements, medications, and other xenobiotics in epidemiologic surveys is usually obtained from questionnaires subject to recall reporting biases. The authors used metabolite data hydrogen-1 (or proton) nuclear magnetic resonance (1H NMR) analysis of human urine specimens the International Study Macro-/Micro-Nutrients Blood Pressure (INTERMAP Study) validate self-reported analgesic use. Metabolic profiling two 24-hour per individual was carried out for 4,630...
Dentists with a special interest hold enhanced skills enabling them to treat cases of intermediate complexity. The aim this study was explore primary dental care practitioners' views dentists (DwSIs) in Endodontics London, reference an educational and service initiative established by (the former) London Deanery conjunction the NHS. A cross-sectional postal survey working across different models within conducted, target achieve at least 5 % London's dentists. questionnaire instrument...