- Blood Pressure and Hypertension Studies
- Medication Adherence and Compliance
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Sodium Intake and Health
- Hormonal Regulation and Hypertension
- Heart Rate Variability and Autonomic Control
- Lipoproteins and Cardiovascular Health
- Obesity, Physical Activity, Diet
- HIV/AIDS drug development and treatment
- Global Public Health Policies and Epidemiology
- HIV Research and Treatment
- Nutritional Studies and Diet
- Cardiovascular Health and Disease Prevention
- Mobile Health and mHealth Applications
- Pharmaceutical Practices and Patient Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- Treatment of Major Depression
- Diabetes Treatment and Management
- Smoking Behavior and Cessation
- Migraine and Headache Studies
- Tryptophan and brain disorders
- Cardiovascular Health and Risk Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac, Anesthesia and Surgical Outcomes
The George Institute for Global Health
2016-2025
The University of Sydney
2015-2025
UNSW Sydney
2015-2025
Merck & Co., Inc., Rahway, NJ, USA (United States)
2012-2025
George Institute for Global Health
2014-2025
National Health and Medical Research Council
2004-2024
George Institute for Global Health
2013-2024
University of Oxford
2000-2024
Tropical Population Health Unit
2024
Imperial College London
2017-2024
In patients with type 2 diabetes, the effects of intensive glucose control on vascular outcomes remain uncertain.We randomly assigned 11,140 diabetes to undergo either standard or control, defined as use gliclazide (modified release) plus other drugs required achieve a glycated hemoglobin value 6.5% less. Primary end points were composites major macrovascular events (death from cardiovascular causes, nonfatal myocardial infarction, stroke) and microvascular (new worsening nephropathy...
Reliable and comparable analysis of risks to health is key for preventing disease injury. Causal attribution morbidity mortality risk factors has traditionally been conducted in the context methodological traditions individual factors, often a limited number settings, restricting comparability.In this paper, we discuss conceptual issues quantifying population effects or groups various levels causality using knowledge from different scientific disciplines. The include: comparing burden due...
To determine the effectiveness of a mobile phone text messaging smoking cessation programme.Randomised controlled trialNew Zealand1705 smokers from throughout New Zealand who wanted to quit, were aged over 15 years, and owned randomised an intervention group that received regular, personalised messages providing advice, support, distraction, or control group. All participants free month messaging; starting for on their quit day assist with quitting, at six months encourage follow up. Follow...
The last few years have seen a considerable increase in the amount of information available concerning blood pressure (BP) and stroke associations. This article provides an overview published reviews effects on trials BP-lowering drugs compares these with results from cohort studies.We present review major overviews prospective studies updated meta-analysis >40 randomized controlled BP lowering, which included >188 000 participants approximately 6800 events. Cohort now indicate that Asia...
IMPORTANCE Cardiovascular disease prevention, including lifestyle modification, is important but underutilized.Mobile health strategies could address this gap lack evidence of therapeutic benefit.OBJECTIVE To examine the effect a lifestyle-focused semipersonalized support program delivered by mobile phone text message on cardiovascular risk factors. DESIGN AND SETTINGThe Tobacco, Exercise and Diet Messages (TEXT ME) trial was parallel-group, single-blind, randomized clinical that recruited...
Background Cardiovascular diseases and their nutritional risk factors—including overweight obesity, elevated blood pressure, cholesterol—are among the leading causes of global mortality morbidity, have been predicted to rise with economic development. Methods Findings We examined age-standardized mean population levels body mass index (BMI), systolic total cholesterol in relation national income, food share household expenditure, urbanization a cross-country analysis. Data were from over 100...