A5008211883- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Enhanced Recovery After Surgery
- Trauma and Emergency Care Studies
- Patient-Provider Communication in Healthcare
- Pancreatic function and diabetes
- Peripheral Artery Disease Management
- Cancer survivorship and care
- Cerebrovascular and Carotid Artery Diseases
- Neuropeptides and Animal Physiology
- Sepsis Diagnosis and Treatment
- Adrenal Hormones and Disorders
- Control Systems in Engineering
- Disaster Response and Management
- Hydraulic and Pneumatic Systems
- Iterative Learning Control Systems
- Emergency and Acute Care Studies
- Aortic Disease and Treatment Approaches
- Regulation of Appetite and Obesity
- Retirement, Disability, and Employment
- Health Systems, Economic Evaluations, Quality of Life
- Social and Educational Sciences
- Pharmaceutical studies and practices
- Receptor Mechanisms and Signaling
- Diabetes Treatment and Management
AstraZeneca (Sweden)
2024
University of Gothenburg
2012-2023
Sahlgrenska University Hospital
2012-2023
Linköping University
1995-2009
ABB (Sweden)
2009
Uppsala Monitoring Centre
1996-2005
The University of Sydney
2001
Humboldt-Universität zu Berlin
1999-2000
Södertälje Sjukhus
2000
Charité - Universitätsmedizin Berlin
1999
Aims Drug-induced QTc-prolongation, resulting from inhibition of HERG potassium channels may lead to serious ventricular arrhythmias and sudden death. We studied the quantitative anti-HERG activity pro-arrhythmic drugs as a risk factor for this outcome in day-to-day practice. Methods results All 284 426 case reports suspected adverse drug reactions with known received by International Drug Monitoring Program World Health Organization (WHO-UMC) up first quarter 2003, were used calculate...
Objective: To identify, classify, and describe safety hazards during the process of intrahospital transport critically ill patients. Design: A prospective observational study. Data from participant observations were collected over a period 3 months. Setting: The study was undertaken at two ICUs in one university hospital. Patients: Critically patients transported within hospital by critical care nurses, unlicensed physicians. Interventions: None. Measurements Main Results: Content analysis...
By using engine control during the gear shift, a manual transmission can be automated without clutch shift event. It is then important to minimize total time needed for but when doing so driveline resonances may excited. This in turn lead problems with disengaging old and synchronizing speeds engaging new gear. Internal torque novel idea handling increasing quality. estimating transmitted controlling it zero by control, systematically disengaged minimized driver disturbances faster speed...
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> This paper presents an optimization strategy for finding the trade-offs between cost, lifetime, and performance when designing drive train, i.e., gearboxes electric motors, new robot concepts. The method is illustrated with example in which trains of two principal axes on a six-axis serial manipulator are designed. Drive train design industrial robots complex task that requires concurrent...
Abdominal aortic aneurysm (AAA) is a ballooning-out of the aorta that does not normally give any symptoms. Undetected and untreated an can rupture, which in most cases fatal. Mass screening 65-year old men for early detection AAA and, selected cases, operation seem to reduce mortality due although, has reduced overall this group. In Västra Götaland, southwest part Sweden, amongst started 2009. There are controversies within medical community about benefits adverse effects screening. order...
Many existing patient-reported outcome measures are extensive regarding both patient burden and administration, in terms of analysing reporting results. The VascuQoL-6 (VQ6) – a short version the original Vascular Quality Life Questionnaire (VascuQoL), disease-specific instrument for peripheral arterial disease was recently developed. However, VQ6 has not yet been empirical tested with regard to content validity, construct validity test retest reliability. Our aim was, therefore, explore...
Islet amyloid polypeptide (IAPP), also known as amylin, has previously been demonstrated to occur in deposits pancreatic islets type 2 diabetics, and, therefore, the peptide suggested be involved pathogenesis of diabetes. The 37 amino acid shows approximately 50% homology with intrapancreatic neuropeptide calcitonin gene‐related (CGRP), a that inhibits insulin secretion. We therefore examined, model experiments mice and rats, if IAPP exerts this effect. was given intravenously, at dose...
Traditional outcome measures in peripheral arterial disease (PAD) provide insufficient information regarding patient benefit. It has therefore been suggested to add patient-reported measures. The main aim of this study was validate the Swedish Vascular Quality Life questionnaire (VascuQoL) version, a PAD-specific health-related quality life (HRQoL) instrument. Two-hundred PAD patients were consecutively recruited from two university hospitals. Out 200 subjects, 129 had intermittent...
To describe preoperative communication after a person-centred intervention in nurses' consultations with patients undergoing surgery for colorectal cancer.Patients all over the world scheduled are referred to healthcare professionals. The goal is assess risk of perioperative complications, improving quality care and enabling be prepared recovery. A was developed, which consisted an interactive written patient education material communication.An explorative quantitative qualitative study...
Neuropeptide Y (NPY) and calcitonin gene-related peptide (CGRP) are both intrapancreatic neuropeptides that known to inhibit stimulated insulin secretion. In the present study, we examined their influences on basal glucagon secretion in mouse. Either NPY or CGRP was injected intravenously at two dose levels (0.85 4.25 nmol/kg). When alone, neither of them did affect plasma but reduced levels. Glucagon by cholinergic agonist carbachol modestly inhibited nmol/kg (P<0.01) not affected CGRP....
Abdominal aortic aneurysm can be treated using 3 different methods: open repair, endovascular or conservative treatment with regular monitoring and postponement of surgery until the is greater than 55 mm. Conservative entails living knowledge that an present while undergoing annual outpatient follow-up.This study describes patients' experiences they have for which are receiving treatment.A qualitative, phenomenological-hermeneutic approach was used. Interviews were conducted between April...
In interview studies, men under surveillance for screening-detected abdominal aortic aneurysms have reported ambivalence towards this diagnosis: the knowledge was welcomed together with worries, feelings of anxiety and existential thoughts about life's fragility mortality due to diagnosis. Previous surveys health-related quality life aspects among aneurysm all used generic patient-reported outcomes. Therefore, aim study extend core-questionnaire Consequences Screening use in screening by...
The assessment and evaluation of practical sustainable development health care has become a major focus investigation in services research. A key challenge for researchers as well decision-makers is to understand mechanisms influencing how complex interventions work embedded practice, which significant both later implementation. In this study, we explored nurses' surgeons' perspectives on performing participating multi-centre person-centred intervention process that aimed support patients...
To meet patients' information and communication needs over time in order to improve their recovery is particularly challenging for patients undergoing cancer surgery. The aim of the study was evaluate whether an intervention with a person-centred approach diagnosed colorectal surgery can preparedness surgery, discharge during six months following diagnosis initial treatment. components involving novel written interactive patient education material based on critical analysis conventional...
The preoperative education, which occurs in patient consultations, is an important part of the surgical nurse's profession. These consultations may be building blocks a partnership that facilitates communication between and nurse.The aim study was to describe topics structure documentation nursing with patients undergoing surgery for colorectal cancer.The based on analysis seven nurses at Swedish university hospital. preplanned were audio-recorded transcribed verbatim. described terms phases...
Abstract: Series of well‐documented case reports strongly suggest a causal association between tiaprofenic acid and form aseptic cystitis, which can cause serious long‐term morbidity if the drug is not withdrawn promptly. These findings are supported in Australian UK spontaneous reporting data‐bases. Using sales data as denominator, comparison NSAIDs WHO monitoring data‐base indicates that reaction specific to cannot be accounted for by changes patterns certain countries or years. Delayed...