A5052647764- Pharmacovigilance and Adverse Drug Reactions
- Pharmaceutical studies and practices
- Pharmaceutical Economics and Policy
- Computational Drug Discovery Methods
- Pharmaceutical Practices and Patient Outcomes
- Academic integrity and plagiarism
- Biosimilars and Bioanalytical Methods
- Statistical Methods in Clinical Trials
- Pharmaceutical industry and healthcare
- Pharmacogenetics and Drug Metabolism
- Health Systems, Economic Evaluations, Quality of Life
- Analytical Methods in Pharmaceuticals
- Drug-Induced Adverse Reactions
- Drug-Induced Hepatotoxicity and Protection
- Ethics in Clinical Research
- Biomedical Text Mining and Ontologies
- Drug Transport and Resistance Mechanisms
- Epilepsy research and treatment
- Patient Safety and Medication Errors
- Cancer Treatment and Pharmacology
- Heavy Metal Exposure and Toxicity
- Autoimmune Bullous Skin Diseases
- Clinical practice guidelines implementation
- Medical Malpractice and Liability Issues
- Venous Thromboembolism Diagnosis and Management
Aston University
2024
Uppsala Monitoring Centre
2012-2023
Drug Safety Research Unit
2023
Kettering General Hospital
2021
Center of Immunology Pierre Fabre
2017
Stockholm University
2012
Uppsala University
2010
Brunel University of London
2010
Utrecht University
2010
Women Helping Others Foundation
2005-2007
Thirty three reports of cough associated with captopril and 26 enalapril received by the New Zealand intensive medicines monitoring programme were reviewed. The is a specialised part postmarketing surveillance system. Review these showed that was an adverse reaction to drugs, occurred even low dose treatment, severe enough warrant withdrawal drugs in most cases reported. A significant sex difference shown, women predominating. seemed be greater problem enalapril, seven patients it both...
Post-marketing drug safety data sets are often massive, and entail problems with heterogeneity selection bias. Nevertheless, quantitative methods have proven a very useful aid to help clinical experts in screening for previously unknown associations these sets. The WHO international database is the world's largest set of its kind over three million reports on suspected adverse reaction incidents. Since 1998, an exploratory analysis method has been routine use screen this set. This was...
Interaction between drug substances may yield excessive risk of adverse reactions (ADRs) when two drugs are taken in combination. Collections individual case safety reports (ICSRs) related to suspected ADR incidents clinical practice have proven be very useful post-marketing surveillance for pairwise drug--ADR associations, but yet reach their full potential drug-drug interaction surveillance. In this paper, we implement and evaluate a shrinkage observed-to-expected ratio exploratory...
The rapid expansion of the Internet and computing power in recent years has opened up possibility using social media for pharmacovigilance. While this general concept been proposed by many, central questions remain as to whether can provide earlier warnings rare serious events than traditional signal detection from spontaneous report data. Our objective was examine specific product–adverse event pairs were reported via before being US FDA Adverse Event Reporting System (FAERS). A...
A number of safety signals—complex regional pain syndrome (CRPS), postural orthostatic tachycardia (POTS), and chronic fatigue (CFS)—have emerged with human papillomavirus (HPV) vaccines, which share a similar pattern symptomatology. Previous signal evaluations epidemiological studies have largely relied on traditional methodologies signals been considered individually. The aim this study was to explore global reporting patterns for HPV vaccine subgroups reports adverse event (AE) profiles....
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Abstract Publication of case reports describing suspected adverse effects drugs and medical products that include herbal complementary medicines, vaccines, other biologicals devices is important for postmarketing surveillance. lends credence to signals raised in these event reports. Unfortunately, deficiencies vital information published cases can often limit the value such by failing provide sufficient details either (i) a differential diagnosis or provisional assessment cause‐effect...