A5011721425- Retinal Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Retinal Development and Disorders
- Advanced MRI Techniques and Applications
- Diet and metabolism studies
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Satellite Communication Systems
- Advanced Optical Network Technologies
- Adipose Tissue and Metabolism
- Glaucoma and retinal disorders
- Software-Defined Networks and 5G
- Neuroscience and Neuropharmacology Research
- Natural product bioactivities and synthesis
- Medicinal Plant Pharmacodynamics Research
- Acute Ischemic Stroke Management
- Receptor Mechanisms and Signaling
- Ocular Diseases and Behçet’s Syndrome
- Parathyroid Disorders and Treatments
- Cardiac Imaging and Diagnostics
- Ion channel regulation and function
- Cerebrovascular and Carotid Artery Diseases
- Neurological Disease Mechanisms and Treatments
- Advanced Photonic Communication Systems
Zhoushan Hospital
2025
Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine
2025
China Mobile (China)
2021-2024
Qilu Hospital of Shandong University
2008-2023
Zhengzhou University
2021-2023
Yuhuangding Hospital
2009-2023
Qingdao University
2018-2023
Nanjing University
2023
Guangzhou University of Chinese Medicine
2021
Anhui University of Traditional Chinese Medicine
2019
Regional satellite networks are capable of supporting denser coverage and more reliable communications in the target area hence have been viewed as an essential part sixth generation (6G) communication system. Since time-varying limited resources, efficient resource management schemes needed to accommodate massive ubiquitous service requests. As a remedy, virtual network embedding (VNE) can enable diverse requests (VNRs) share same substrate resources improve utilization. However, existing...
To clarify dynamic change of quality life (QOL) in patients with stroke after treatment, and to explore the predictors associated return work (RTW) within 48 weeks.Patients diagnosed were enrolled. All enrolled asked fill Short Form 36 Health Survey. For stroke, SF-36 questionnaires measured repeatedly 4 weeks treatment. We used phone call find out if patient was RTW. The investigation time had lower scores terms physiological dimensions, such as physical functional, role limitations due...
The ongoing roll-out of cloud–edge computing and Internet Things (IoT) has been simulating the boom new advance reservation (AR) services, such as bulk-data migration virtual machine backup, driving development substrate elastic optical networks (EONs). These AR requests are initial-delay-insensitive if they guaranteed to be completed before a predefined deadline. Therefore, routing, modulation, spectrum assignment (RMSA) problem is extended time-spectrum domain rather than single domain....
African Americans (AAs) are underrepresented in pharmacogenomics which has led to a significant gap knowledge. AAs admixed and can inherit specific loci from either their or European ancestor, known as local ancestry (LA). A previous study identified single nucleotide polymorphisms (SNPs) located the CYP2C cluster that associated with warfarin dose. However, LA was not considered this study. An IWPC cohort (N=340) used determine LA-adjusted association Ancestry-specific GWAS's were conducted...
Abstract Guillain-Barré syndrome (GBS) is a neurological disorder characterized by paralysis. Identifying the severity, appropriate therapeutic method, and prognosis of GBS at an early stage highly important. This study aimed to investigate modifiable risk factors for severity consequent need mechanical ventilation (MV) identify clinical predictive poor short-term outcomes severe GBS. 155 patients who were admitted Affiliated Yantai Yuhuangding Hospital Qingdao University during 2014–2020...
Objectives: Estrogen is known to prominently benefit neuronal syndromes and neurodegenerative diseases. Ginsenoside Rg1, an active ingredient found in a Chinese plant, ginseng root, was previously demonstrated exert estrogen-like activity. This study performed assess the neuroprotective effect of ginsenoside Rg1 against apoptosis induced by β-amyloid protein 25–35 (Aβ25–35) primary cultured rat hippocampal cells as well underlying mechanisms.Methods: We first measured cell viability lactate...
To detect diffuse myocardial fibrosis in different severity levels of left ventricular diastolic dysfunction (DD) spontaneous type 2 diabetes mellitus (T2DM) rhesus monkeys.Eighteen T2DM and nine healthy monkeys were studied. Echocardiography was performed for function classification. Cardiac magnetic resonance (CMR) imaging to obtain extracellular volume fraction (ECV) maps T1ρ at two spin-locking frequencies. ECV values, index (mFI) values which are based on the dispersion T1ρ, calculated....
Atherosclerosis is one of the main risk factors cause acute cerebral-cardio vascular diseases. It's great significance to establish an atherosclerosis animal model that can mimic characteristics and nature course human patients. Therefore, a rhesus monkey was induced by high-fat diet monitor their lipid profile intima-media thickness (IMT) artery walls study progression. Fifty male monkeys were enrolled in this study. All these aged 7 14 years with BMI >30 kg/m2. They fed containing 10% fat...
With the 5G worldwide deployment, scale of vertical applications is innovated benefit from technologies including MEC (Multi-access Edge Computing), network slicing, etc. Especially for healthcare, had been used COVID-19 protection and intelligent medical processing. However, limited by hospital's traditional information infrastructures, those 5G-based healthcare are hard to be deployed most only demonstration, also isolated existing systems. So what next generation smart infrastructures key...
Diastolic heart failure is a common and deadly complication of diabetes mellitus, with the development diabetic cardiomyopathy as one key determinants disease's complex pathology. The cause association unknown has no approved therapy strategies yet. However significant advances in this area may come from studies on suitable animal models.A total 25 male rhesus monkeys (12-16 years, 9-13 kg) were enrolled. Fifteen them diagnosed spontaneous type 2 mellitus (T2DM, FPG ≥ 104 mg/dl, HbA1c:...
Purpose: To describe the ocular phenotype of spontaneous glaucoma in a non-human primate colony. Methods: In total, 722 Rhesus macaque monkeys aged 10 to 25 years underwent optical coherence tomography (OCT), fundus photography (FP), and intraocular pressure (IOP) measurements. Monkeys with baseline cup-to-disc ratio (CDR) <0.5 were used establish features. A subset was followed longitudinally for three compared suspects on basis OCT/FP criteria. Results: The average IOP under ketamine...
Spontaneous T2DM in rhesus monkeys manifests as isolated diastolic dysfunction the early stage of diabetic cardiomyopathy, similar to humans. Myocardial deformation measurements have emerged a superior way measure left ventricular (LV) function cardiac dysfunction, making it possible further evaluate early-stage LV spontaneous monkeys.Spontaneous with (T2DM-DD, n = 10) and corresponding nondiabetic healthy animals (ND, 9) were prospectively scanned for CMR study. Circumferential longitudinal...
Type 2 diabetes mellitus (T2DM) is the most common form of diabetes. To determine similarities development T2DM between rhesus monkey [Macaca mulatta lasiotis (M. m. lasiotis)] and human being, clinical parameters were determined during a period years in 60 adult male monkeys lasiotis).Sixty whose fasting plasma glucose (FPG) level less than or equal to 5 mmol/L (90 mg/dL) enrolled this study. Of these, 50 aged 7 20 fed with high-fat diet 10 4 standard as normal monkeys. Body weight, body...
Purpose: To evaluate the efficacy of a therapy on improving characteristics laser-induced choroidal neovascularization (CNV) via single intravitreal injection humanized anti-human VEGF monoclonal antibody (PRO-169) versus bevacizumab in rhesus monkey model. Methods: induce experimental CNV, small high-energy laser spots were used to treat several areas, around macula retinas monkeys at Day −21. Eighteen for CNV induction. The endpoints fluorescein leakage by FFA and retinal thickness OCT....
The neuroprotective effects of Bu-Wang-San (BWS) and its on spine synapse plasticity were investigated in ovariectomised rats.Thirty-six rats divided into three groups: untreated controls, treatment with 17beta-estradiol or BWS. After 3 months, spatial acquisition retention measured using the Morris water maze. Swim time, swim distance, speed, quadrant time platform crossing recorded. Spine density hippocampus was examined by transmission electron microscopy. expression synaptophysin P38...
BACKGROUND Sleep deprivation (SD) is common in humans, and sleep loss has a significant influence on health produces related diseases. Orexin-A been demonstrated to play role physiological processes, including feeding, sleep/wake cycle, energy metabolism. The aim of this study was investigate the effect SD rats define underlying mechanism. MATERIAL AND METHODS We constructed an rat model. Morris water maze test used assess learning memory. Imaging hippocampus hippocampal tissue were captured...
Abstract Background Autonomic dysfunctions including bladder dysfunction, gastrointestinal dysfunction and orthostasis are common symptoms of autoimmune glial fibrillary acidic protein astrocytopathy (A-GFAP-A); however, cardiac autonomic abnormal circadian rhythm blood pressure, which can lead to poor prognosis even sudden death, has never been reported in A-GFAP-A patient. Case presentation A 68-year-old male Chinese patient presented our hospital with headache, fever, progressive...