- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Health Systems, Economic Evaluations, Quality of Life
- Patient-Provider Communication in Healthcare
- Healthcare cost, quality, practices
- Lung Cancer Diagnosis and Treatment
- Health Promotion and Cardiovascular Prevention
- BRCA gene mutations in cancer
- Knee injuries and reconstruction techniques
- Chronic Disease Management Strategies
- Lung Cancer Treatments and Mutations
- Mental Health and Psychiatry
- Total Knee Arthroplasty Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Cancer survivorship and care
- Radiology practices and education
- Cardiac, Anesthesia and Surgical Outcomes
- Cervical Cancer and HPV Research
- Aortic aneurysm repair treatments
- Clinical practice guidelines implementation
- Radiation Dose and Imaging
- Delphi Technique in Research
- Palliative Care and End-of-Life Issues
- Ultrasound in Clinical Applications
- Education, Healthcare and Sociology Research
University of Copenhagen
2016-2025
Region Zealand
2016-2025
UiT The Arctic University of Norway
2022-2025
Hospital South West Jutland
2022-2025
University of Southern Denmark
2020-2025
Centre for Arctic Gas Hydrate, Environment and Climate
2023-2024
Primary HealthCare
2018-2024
Primary Health Care
2017-2024
IS practice
2023
University Medical Center of the Johannes Gutenberg University Mainz
2023
<h3>Background</h3> The effects of low-dose CT screening on disease stage shift, mortality and overdiagnosis are unclear. Lung cancer findings rates reported at the end in Danish Cancer Screening Trial. <h3>Methods</h3> 4104 men women, healthy heavy smokers/former smokers were randomised to five annual screenings or no screening. Two experienced chest radiologists read all scans registered location, size morphology nodules. Nodules between 5 15 mm without benign characteristics rescanned...
<h3>PURPOSE</h3> Cancer screening programs have the potential of intended beneficial effects, but they also inevitably unintended harmful effects. In case mammography, most frequent harm is a false-positive result. Prior efforts to measure their psychosocial consequences been limited by short-term follow-up, use generic survey instruments, and lack relevant benchmark—women with breast cancer. <h3>METHODS</h3> this cohort study 3-year we recruited 454 women abnormal findings in mammography...
As of April 2015, participants in the Danish Lung Cancer Screening Trial had been followed for at least 5 years since their last screening.Mortality, causes death, and lung cancer findings are reported to explore effect computed tomography (CT) screening.A total 4,104 aged 50-70 time inclusion with a minimum 20 pack-years smoking were randomized have five annual low-dose CT scans (study group) or no screening (control group).Follow-up information regarding date cause diagnosis, stage,...
Peter Gotzsche and colleagues argue that women are still not given enough, nor correct, information about the harms of screening
According to the Wonca International Dictionary for General/Family Practice Quaternary Prevention is defined as: 'Action taken identify patient at risk of overmedicalization, protect him from new medical invasion, and suggest interventions, which are ethically acceptable.' The concept quaternary prevention was initially proposed by Marc Jamoulle targets were mainly patients with illness but without a disease.The purpose this opinion article open debate around possible definition conceptual...
Communication that empowers the public, patients, clinicians, and policy makers to think differently about overdiagnosis will help support a more sustainable healthcare future for all, argue <b>Kirsten McCaffery colleagues</b>
Precision medicine based on big data promises to revolutionise disease prevention but increases the challenge of determining which abnormalities will be clinically important, argue <b>Henrik Vogt and colleagues</b>
The ethical and societal implications of artificial intelligence systems raise concerns. In this article, we outline a novel process based on applied ethics, namely, Z-Inspection <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> , to assess if an AI system is trustworthy. We use the definition trustworthy given by high-level European Commission's expert group AI. general inspection that can be variety domains where are used, such as...
Abstract Objective To report on complications of conisation and its effects fertility stenosis. Design Register based nationwide cohort study routinely collected data using several linked databases. Setting Primary secondary care in Denmark, 2006-18. Population The comprised 48 048 conisations women aged 23-65 who had undergone within 120 days a cervical biopsy. biopsy biopsies but not were matched by age time procedure. Women excluded from the before long term outcome analyses if they...
‘Nudging—and the underlying idea ‘libertarian paternalism’—to an increasing degree influences policy thinking in healthcare sector. This article discusses influence exerted upon a woman's choice of participation Danish breast screening programme light paternalism’. The basic tenet paternalism’ is outlined and relationship between informed consent investigated. Key elements process enrolling women into mammography are introduced. It shown that for several reasons women's choices cannot be...
This study analyzes data from the Danish Lung Cancer Screening Trial to determine amount of overdiagnosis computed tomography–detected lung cancer.
Abstract The purpose of this article was to introduce the reader nature patient‐reported outcome measures (PROMs) and pitfalls in their use. PROMs collect subjective information directly from patient regarding specific or general conditions add clinical functional outcomes, turn unmeasurable qualities into quantitative measures. are questionnaires consisting items: questions statements with predefined response options. items an adequate PROM have been developed by involvement patients...
This paper documents how an ethically aligned co-design methodology ensures trustworthiness in the early design phase of artificial intelligence (AI) system component for healthcare. The explains decisions made by deep learning networks analyzing images skin lesions. trustworthy AI developed here used a holistic approach rather than static ethical checklist and required multidisciplinary team experts working with designers their managers. Ethical, legal, technical issues potentially arising...
Abstract Background The use of point-of-care ultrasonography (POCUS) performed by general practitioners (GPs) in primary care settings is increasing. Previous studies have focused on GP-reported outcomes and little known about patients’ perspectives the POCUS technology within practice consultation. purpose this study was to examine experiences with areas where GPs indicated that affected aspects Methods A questionnaire developed using a mixed methods sequential design. Analytical themes...
The knee injury and Osteoarthritis Outcome Score (KOOS), based on the Western Ontario McMaster Universities Index (WOMAC), is widely used to evaluate subjective outcome in anterior cruciate ligament (ACL) reconstructed patients. However, validity of KOOS has not been assessed using Rasch analysis. objective this study was viability as an measure for ACL reconstruction partial credit model. analysis applied 200 questionnaires completed by patients consecutively tested 20 weeks after...