- Pharmaceutical industry and healthcare
- Healthcare cost, quality, practices
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Health and Medical Research Impacts
- Patient-Provider Communication in Healthcare
- Global Public Health Policies and Epidemiology
- Global Cancer Incidence and Screening
- Primary Care and Health Outcomes
- Ethics in Clinical Research
- Clinical practice guidelines implementation
- Healthcare Systems and Challenges
- Healthcare Policy and Management
- Health Services Management and Policy
- Sexual function and dysfunction studies
- Medical Malpractice and Liability Issues
- Health Policy Implementation Science
- Health Promotion and Cardiovascular Prevention
- Mental Health and Psychiatry
- Science, Research, and Medicine
- Child and Adolescent Health
- Thyroid Cancer Diagnosis and Treatment
- Meta-analysis and systematic reviews
- Social Media in Health Education
- Climate Change Communication and Perception
Bond University
2016-2025
The University of Sydney
2016-2025
Evidence Based Research (United States)
2022
Sheffield Teaching Hospitals NHS Foundation Trust
2020
Royal College of Anaesthetists
2019-2020
Royal College of Surgeons of England
2019-2020
Royal College of Surgeons of Edinburgh
2019-2020
Sydney Local Health District
2020
Northern General Hospital
2019-2020
Gold Coast Health
2019
Evidence is mounting that medicine harming healthy people through ever earlier detection and wider definition of disease. With the announcement an international conference to improve understanding problem overdiagnosis, Ray Moynihan , Jenny Doust David Henry examine its causes explore solutions
The news media are an important source of information about new medical treatments, but there is concern that some coverage may be inaccurate and overly enthusiastic.
Thirty years ago, Henry Gadsden, the head of Merck, one world's largest drug companies, told Fortune magazine that he wanted Merck to be more like chewing gum maker Wrigley's. It had long been his dream make drugs for healthy people so could sell everyone. Gadsden's now drives marketing machinery most profitable industry on earth. Drug companies are systematically working widen very boundaries define illness, and markets medication grow ever larger. Mild problems redefined as serious...
Thanya Pathirana and colleagues explore strategies to tackle the problem of too much medicine
The Guest Editors of the Disease Mongering theme issue argue that we need better research to identify, understand, and combat threat human health from corporate-sponsored selling sickness.
Ray Moynihan examines the role of influential experts paid by industry to help “educate” profession and public
<h3>Background:</h3> Without stimulation, the human brain spontaneously produces highly organized, low-frequency fluctuations of neural activity in intrinsic connectivity networks (ICNs). Furthermore, without adequate explanatory nociceptive input, patients with somatoform pain disorder experience symptoms, thus implicating a central dysregulation homeostasis. The present study aimed to test whether interactions among pain-related ICNs, such as default mode network (DMN), cingular–insular...
Communication that empowers the public, patients, clinicians, and policy makers to think differently about overdiagnosis will help support a more sustainable healthcare future for all, argue <b>Kirsten McCaffery colleagues</b>
We all want to make healthcare decisions based on trustworthy evidence.Yet the landmark 2009 Institute of Medicine report identified widespread financial conflicts interest across medical research, education, and practice.(1) It highlighted that extensive industry influence may be jeopardizing "the integrity scientific investigations, objectivity quality patient care, public's trust in medicine."(1) At same time there's increasing appreciation nations within clinical communities problem too...
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Organizations have been established in many countries and internationally to support the use of research evidence by producing clinical practice guidelines, undertaking health technology assessments, and/or directly supporting developing policy on an international, national, state or provincial level. Learning from these organizations can reduce need 'reinvent wheel' inform decisions about how best organize for such organizations, particularly low- middle-income (LMICs).We undertook a...
Ray Moynihan and colleagues outline suggestions for improving the way that medical evidence is produced, analysed, interpreted to avoid problems of overdiagnosis overtreatment. Please see later in article Editors' Summary
There is growing acceptance that the increase in thyroid cancer incidence part a result of overdiagnosis small low-risk papillary microcarcinomas (PMCs) with indolent clinical course. Although surgery cornerstone treatment for patients PMCs, recent management guidelines are shifting toward inclusion more conservative treatments such as active surveillance. little evidence on clinicians' experience managing PMC and their attitudes options, including willingness to accept nonsurgical option....
Background Despite evidence about the "modern epidemic" of overdiagnosis, and expanding disease definitions that medicalize more people, data are lacking on public views these issues. Our objective was to measure perceptions overdiagnosis financial ties panels setting definitions. Methods We conducted a 15 minute Computer Assisted Telephone Interview with randomly selected community sample 500 Australians in January 2014. iteratively developed piloted questionnaire, convenience (n=20), then...
To investigate the nature and extent of financial relationships between leaders influential professional medical associations in United States pharmaceutical device companies.Cross sectional study.Professional for 10 costliest disease areas US according to Agency Healthcare Research Quality. Financial data association leadership, 2017-19, were obtained from Open Payments database.328 leaders, such as board members, associations: American College Cardiology, Orthopaedic Trauma Association,...
In recent years management practices in relation to low-risk papillary microcarcinoma (PMC) have been evolving with increased awareness of the potential overdiagnosis and overtreatment PMCs, guidelines recommendations for non-surgical options such as active surveillance. This study aimed develop an in-depth understanding patients' experiences communication their PMC diagnosis, treatment preferences decision making. Semi-structured qualitative interviews 25 patients diagnosed pre-operatively...
<h3>Importance</h3> Given evidence of overdiagnosis and overtreatment small papillary thyroid cancers (PTCs), strategies are needed to promote the consideration less invasive treatment options for patients with low-risk PTC. <h3>Objective</h3> To determine association preferences anxiety levels PTC terminology used describe condition. <h3>Design, Setting, Participants</h3> This randomized crossover study involved a community sample 550 Australian men women 18 years or older without history...