Keiko Wada

ORCID: 0000-0002-5467-8592
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About
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Research Areas
  • Nutritional Studies and Diet
  • Cancer Risks and Factors
  • Birth, Development, and Health
  • Adipokines, Inflammation, and Metabolic Diseases
  • Obesity, Physical Activity, Diet
  • Diet and metabolism studies
  • Phytoestrogen effects and research
  • Colorectal Cancer Screening and Detection
  • Circadian rhythm and melatonin
  • Global Cancer Incidence and Screening
  • Diet, Metabolism, and Disease
  • Sleep and related disorders
  • Liver Disease Diagnosis and Treatment
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Adipose Tissue and Metabolism
  • Regulation of Appetite and Obesity
  • Consumer Attitudes and Food Labeling
  • Metabolism, Diabetes, and Cancer
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Urban Stormwater Management Solutions
  • Smoking Behavior and Cessation
  • Multiple and Secondary Primary Cancers
  • Respiratory Support and Mechanisms
  • Ovarian cancer diagnosis and treatment
  • Family and Patient Care in Intensive Care Units

Gifu University
2016-2025

Kyoto University
2018-2024

IQVIA (United States)
2018-2024

Prevention Institute
2024

National Center of Neurology and Psychiatry
2021-2023

Yokohama City University
2021-2023

Ministry of Education, Culture, Sports, Science and Technology
2007-2023

October 6 University
2023

Lake Biwa Museum
2010-2022

Osaka National Hospital
2018-2022

The association between long sleep duration and mortality appears stronger in East Asian populations than North American or European populations.To assess the sex-specific all-cause major-cause a pooled longitudinal cohort to stratify by age body mass index.This study of individual-level data from 9 cohorts Asia Cohort Consortium was performed January 1, 1984, December 31, 2002. final population included participants Japan, China, Singapore, Korea. Mean (SD) follow-up time 14.0 (5.0) years...

10.1001/jamanetworkopen.2021.22837 article EN cc-by-nc-nd JAMA Network Open 2021-09-03

Despite evidence of an association between reproductive factors and endometrial cancer risk, prospective studies have been conducted mainly in non-Asian countries.To assess the factors, such as number deliveries, age at menarche, or menopause, risk.This cohort study used pooled individual data from 13 1963 2014 Asia Cohort Consortium. Participants were Asian women. Data analysis was September 2019 to April 2023.Reproductive assessed using a questionnaire each cohort.The main outcome time...

10.1001/jamanetworkopen.2023.32296 article EN cc-by-nc-nd JAMA Network Open 2023-09-05

Few epidemiologic studies have examined the association between rate of eating and obesity. In this study, we cross-sectionally self-reported with current Body Mass Index (BMI), BMI-change from 20 years age to age.Subjects were 3737 male (mean +/- standard deviation mean BMI deviation: 48.2 7.1 23.3 2.7 kg/m(2)) 1005 female (46.3 7.0 21.8 2.8 Japanese civil servants. We measured categorical eating, BMI, at 20, 20. Energy intake was assessed over a 1-month period brief-type diet history...

10.2188/jea.16.117 article EN cc-by Journal of Epidemiology 2006-01-01

Background— Anti-inflammatory and proinflammatory molecules purportedly play an important role in developing metabolic syndrome (MetS). However, little is known as to the relative importance of these association with MetS. Methods Results— We studied 624 middle-aged Japanese men without medical history cardiovascular disease or cancer investigated associations circulating tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP), adiponectin used respective definitions...

10.1161/01.atv.0000208363.85388.8f article EN Arteriosclerosis Thrombosis and Vascular Biology 2006-02-03

Abstract Biodiesel synthesis by alcoholysis of three vegetable oils (soybean, sunflower and rice bran) catalyzed commercial lipases (Novozym 435, Lipozyme TL‐IM RM‐IM), the optimization enzymes stability over repeated batches is described. The effects molar ratio alcohol to oil reaction temperature with methanol, ethanol, propanol butanol were also studied. All displayed similar kinetics all no significant differences observed. However, each lipase highest activity a different alcohol....

10.1007/s11746-008-1284-0 article EN Journal of the American Oil Chemists Society 2008-08-13

The D-mannose/L-galactose pathway for the biosynthesis of vitamin C (L-ascorbic acid; AsA) has greatly improved understanding this indispensable compound in plants, where it plays multifunctional roles. However, is yet to be proven whether same holds all different organs especially fruit-bearing at stages development. Micro-Tom was used here elucidate mechanisms AsA accumulation and regulation tomato fruits. mRNA expression genes were inversely correlated with increasing content fruits...

10.1093/jxb/err275 article EN cc-by-nc Journal of Experimental Botany 2011-10-06

<h3>Importance</h3> Asia is home to the largest diabetic populations in world. However, limited studies have quantified association of diabetes with all-cause and cause-specific mortality Asian populations. <h3>Objectives</h3> To evaluate investigate potential effect modifications diabetes-mortality associations by participants’ age, sex, education level, body mass index, smoking status. <h3>Design, Setting, Participants</h3> This pooled analysis incorporated individual participant data from...

10.1001/jamanetworkopen.2019.2696 article EN cc-by-nc-nd JAMA Network Open 2019-04-19

The effects of soy or isoflavone intake on breast cancer need to be examined further in epidemiologic studies. We assessed the associations and with incidence a population-based prospective cohort study Japan. Participants were members from Takayama study, aged 35 years older 1992. follow-up was conducted time baseline (September 1, 1992) end March 2008. Cancer mainly confirmed through regional registries. Breast defined as code C50 according ICD-10. Soy intakes validated food frequency...

10.1002/ijc.28088 article EN International Journal of Cancer 2013-02-06

Dietary supplementation with branched-chain amino acids (BCAAs), including leucine, isoleucine, and valine, has shown potential benefits for the metabolic profile. However, higher blood BCAA levels have been associated insulin resistance. To our knowledge, there no study on dietary BCAAs risk of diabetes. We examined association between intake diabetes in a population-based cohort Japan. A total 13,525 residents Takayama City, Japan, who enrolled 1992 responded to follow-up questionnaire...

10.1093/aje/kwt112 article EN American Journal of Epidemiology 2013-09-05

Abstract Serum amino acids, part of a pool free are influenced by metabolism and disease. Few reports exist describing their function concentrations in serum. Our study aimed to determine age- gender-related differences serum acid healthy Japanese patients, focusing on inclusion body proteins. Healthy patients with normal liver kidney were selected based biochemical variables. 23–88-year-old (312 males, 252 females; 52.1±15.0 years) evaluated the values clarify concentration. The divided...

10.1515/cclm-2011-0846 article EN Clinical Chemistry and Laboratory Medicine (CCLM) 2012-05-01

Few studies have examined whether dietary factors might affect blood pressure in children. We purposed to investigate seaweed intake is associated with level among Japanese preschool children.The design of the study was cross-sectional and it conducted autumn 2006. Subjects were healthy preschoolers aged 3-6 years Aichi, Japan. Blood pulse measured once by an automated sphygmomanometer, which uses oscillometric methods. Dietary data, including intake, assessed using 3-day records covering 2...

10.1186/1475-2891-10-83 article EN cc-by Nutrition Journal 2011-08-10

A positive association between body mass index (BMI) and breast cancer risk among postmenopausal women has been reported, a weak inverse suggested premenopausal from studies in the Western population. The effects of BMI on have remained unclear Asian population, especially women.We assessed associations incidence by pooled analysis eight representative large-scale cohort Japan. Cancer was mainly confirmed through regional population-based registries and/or active patient notification major...

10.1093/annonc/mdt542 article EN publisher-specific-oa Annals of Oncology 2014-01-12

Background The proportion of Japanese workers experiencing intense worry or stress during working life is in excess 60%, and the incidence psychiatric disorders suicide due to psychological burden from work duties increasing. To confirm whether response measured by Brief Job Stress Questionnaire (BJSQ) can identify risk for depression, a cohort study was conducted evaluate BJSQ associated with onset depression. Methods A total 1,810 participants aged 20–70 years 2005 completed were...

10.1371/journal.pone.0056319 article EN cc-by PLoS ONE 2013-02-12

Objective To study the association of educational level and risk death from all causes, cardiovascular disease (CVD) cancer among Asian populations. Design A pooled analysis 15 population-based cohort studies. Setting participants 694 434 individuals prospective cohorts within Asia Cohort Consortium. Interventions None. Main outcome measures HRs 95% CIs for all-cause mortality, as well CVD-specific mortality cancer-specific mortality. Results total (mean age at baseline=53.2 years) were...

10.1136/bmjopen-2018-026225 article EN cc-by-nc BMJ Open 2019-08-01

Abstract Background The burden associated with schizophrenia is substantial. Impacts on the individual, healthcare system, and society may be particularly striking within veteran population due to presence of physical mental health comorbidities. Disease also influenced by a complex interplay between social determinants disparities. objective current study was compare non-healthcare societal outcomes veterans without in United States Veterans Health Administration (VHA). Methods A...

10.1186/s12888-022-04022-x article EN cc-by BMC Psychiatry 2022-07-08
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