A5100402008- Arsenic contamination and mitigation
- Heavy Metal Exposure and Toxicity
- Air Quality and Health Impacts
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Cancer Risks and Factors
- Helicobacter pylori-related gastroenterology studies
- Hepatitis B Virus Studies
- Cancer Immunotherapy and Biomarkers
- Gut microbiota and health
- Gastric Cancer Management and Outcomes
- Fluoride Effects and Removal
- Cancer, Lipids, and Metabolism
- Obesity, Physical Activity, Diet
- Epigenetics and DNA Methylation
- BRCA gene mutations in cancer
- Pancreatic and Hepatic Oncology Research
- RNA modifications and cancer
- Retinoids in leukemia and cellular processes
- Nutrition and Health in Aging
- Hepatitis C virus research
- Estrogen and related hormone effects
- Climate Change and Health Impacts
- Animal Genetics and Reproduction
- Colorectal Cancer Screening and Detection
New York University
2016-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2025
Chongqing Cancer Hospital
2022-2025
Chongqing University
2022-2025
Fujian Medical University
2016-2025
Fujian Provincial Cancer Hospital
2015-2025
Chinese Academy of Sciences
2023-2025
Hainan Medical University
2024-2025
Central South University
2009-2025
China Medical University
2020-2025
A longitudinal study of intestinal microbiota in children and their mothers shows that antibiotics, cesarean section, infant formula alter patterns microbial acquisition succession during the first 2 years childhood.
The metalloid arsenic is a natural environmental contaminant to which humans are routinely exposed in food, water, air, and soil.Arsenic has long history of use as homicidal agent, but the past 100 years arsenic, been used pesticide, chemotherapeutic agent constituent consumer products.In some areas world, high levels naturally present drinking water toxicological concern.There several structural forms oxidation states because it alloys with metals covalent bonds hydrogen, oxygen, carbon,...
Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome) and individual variations in the microbiome influence host health, may be implicated disease etiology, affect drug metabolism, toxicity, efficacy. However, molecular basis these microbe-host interactions roles bacterial species are obscure. We now demonstrate a"transgenomic" approach to link metabolic phenotype (metabotype) variation. used combination spectroscopic, microbiomic, multivariate...
There is concern about the potential of an increased risk related to medications that act on renin-angiotensin-aldosterone system in patients exposed coronavirus disease 2019 (Covid-19), because viral receptor angiotensin-converting enzyme 2 (ACE2).We assessed relation between previous treatment with ACE inhibitors, angiotensin-receptor blockers, beta-blockers, calcium-channel or thiazide diuretics and likelihood a positive negative result Covid-19 testing as well severe illness (defined...
Most studies that have evaluated the association between body-mass index (BMI) and risks of death from any cause specific causes been conducted in populations European origin.We performed pooled analyses to evaluate BMI risk among more than 1.1 million persons recruited 19 cohorts Asia. The included approximately 120,700 deaths occurred during a mean follow-up period 9.2 years. Cox regression models were used adjust for confounding factors.In East Asians, including Chinese, Japanese,...
<b>Objective</b> To evaluate the association between arsenic exposure and mortality from cardiovascular disease to assess whether cigarette smoking influences association. <b>Design</b> Prospective cohort study with measured in drinking water wells urine. <b>Setting</b> General population Araihazar, Bangladesh. <b>Participants</b> 11 746 men women who provided urine samples 2000 were followed up for an average of 6.6 years. <b>Main outcome measure</b> Death disease. <b>Results</b> 198 people...
Background: Acquisition of Helicobacter pylori, which predominantly occurs before age 10 years, may reduce risks asthma and allergy. Methods:We evaluated the associations H pylori status with history allergy skin sensitization using data from 7663 adults in Third National Health Nutrition Examination Survey.Adjusted odds ratios (ORs) for currently ever having asthma, allergic rhinitis, symptoms previous year, allergen-specific were computed comparing participants seropositive cagA -or +...
Asthma, a serious health problem worldwide, is becoming more common. Colonization with Helicobacter pylori, major human indigenous (commensal) microbe, during early life may be relevant to the risk of childhood asthma.We conducted cross-sectional analyses, using data from 7412 participants in National Health and Nutrition Examination Survey (NHANES) 1999-2000, assess association between H. pylori asthma.H. seropositivity was inversely associated onset asthma before 5 years age current...
Background The occurrence of diabetes has greatly increased in low- and middle-income countries, particularly Asia, as the prevalence overweight obesity; European-derived populations, obesity are established causes diabetes. shape association with risk its overall impact have not been adequately studied Asia. Methods Findings A pooled cross-sectional analysis was conducted to evaluate between baseline body mass index (BMI, measured weight kg divided by square height m) self-reported status...
The association between increasing body mass index (BMI; calculated as weight in kilograms divided by height meters squared) and risk of breast cancer is unique epidemiology that a crossover effect exists, with reduction before increase after menopause. inverse premenopausal poorly characterized but might be important the understanding causation.
The contamination of groundwater by arsenic in Bangladesh is a major public health concern affecting 35-75 million people. Although it evident that high levels (>300 microg/L) exposure from drinking water are related to adverse outcomes, effects at low-to-moderate (10-300 not well understood. We established the Health Effects Arsenic Longitudinal Study (HEALS) with more than 20,000 men and women Araihazar, Bangladesh, prospectively investigate predominantly (0.1 864 microg/L, mean 99...
Treatment of patients younger than 18 years age with multiple sclerosis has not been adequately examined in randomized trials. We compared fingolimod interferon beta-1a this population.In phase 3 trial, we randomly assigned 10 to 17 relapsing a 1:1 ratio receive oral at dose 0.5 mg per day (0.25 for body weight ≤40 kg) or intramuscular 30 μg week up 2 years. The primary end point was the annualized relapse rate.Of total 215 patients, 107 were and 108 beta-1a. mean 15.3 Among all there 2.4...
BackgroundDiet is a major modifiable risk factor for human health and overall consumption patterns affect planetary health. We aimed to quantify global, regional, national levels of animal-source foods (ASF) inform intervention, surveillance, policy priorities.MethodsIndividual-level dietary surveys across 185 countries conducted between 1990 2018 were identified, obtained, standardised, assessed among children adults, jointly stratified by age, sex, education level, rural versus urban...
Importance Postpartum depression (PPD) is one of the most common mental health conditions during perinatal and postpartum periods, which can have adverse effects on both mother infant. Objective To investigate efficacy perioperative adjunctive esketamine administration after cesarean deliveries in prevention PPD. Design, Setting, Participants A single-center, double-blind, placebo-controlled, randomized clinical trial was conducted from January 1, 2022, to 2023, at Fujian Provincial Hospital...