Jianyi Zhang
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Child Nutrition and Water Access
- Plant Molecular Biology Research
- Agriculture Sustainability and Environmental Impact
- Consumer Attitudes and Food Labeling
- Healthcare Policy and Management
- Sleep and Wakefulness Research
- Nutrition, Genetics, and Disease
- Plant Gene Expression Analysis
- Viral Infections and Outbreaks Research
- Plant Stress Responses and Tolerance
- Primary Care and Health Outcomes
- Sodium Intake and Health
- Global Public Health Policies and Epidemiology
- Diet, Metabolism, and Disease
- Viral Infections and Vectors
- Sunflower and Safflower Cultivation
- Sepsis Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Biomedical Text Mining and Ontologies
- Chronic Disease Management Strategies
- Plant Pathogens and Fungal Diseases
- Horticultural and Viticultural Research
- Cardiovascular Health and Risk Factors
Brigham and Women's Hospital
2023-2025
Guangdong University of Technology
2023-2025
Jilin Agricultural University
2021-2025
University of Alabama at Birmingham
2025
Beijing HuiLongGuan Hospital
2019-2024
Tufts University
2017-2024
Institute of Pomology
2018-2024
Peking University
2024
Chinese Academy of Agricultural Sciences
2018-2024
Shandong University of Science and Technology
2023
BackgroundDiet is a major modifiable risk factor for human health and overall consumption patterns affect planetary health. We aimed to quantify global, regional, national levels of animal-source foods (ASF) inform intervention, surveillance, policy priorities.MethodsIndividual-level dietary surveys across 185 countries conducted between 1990 2018 were identified, obtained, standardised, assessed among children adults, jointly stratified by age, sex, education level, rural versus urban...
Abstract Evidence on what people eat globally is limited in scope and rigour, especially as it relates to children adolescents. This impairs target setting investment evidence-based actions support healthy sustainable diets. Here we quantified global, regional national dietary patterns among adults, by age group, sex, education urbanicity, across 185 countries between 1990 2018, the basis of data from Global Dietary Database project. Our primary measure was Alternative Healthy Eating Index,...
The global burden of diet-attributable type 2 diabetes (T2D) is not well established. This risk assessment model estimated T2D incidence among adults attributable to direct and body weight-mediated effects 11 dietary factors in 184 countries 1990 2018. In 2018, suboptimal intake these was be 14.1 million (95% uncertainty interval (UI), 13.8-14.4 million) incident cases, representing 70.3% (68.8-71.8%) new cases globally. Largest burdens were insufficient whole-grain (26.1% (25.0-27.1%)),...
Sugar-sweetened beverages (SSBs) are associated with cardiometabolic diseases and social inequities. For most nations, recent estimates trends of intake not available; nor variation by education or urbanicity. We investigated SSB intakes among adults between 1990 2018 in 185 countries, stratified subnationally age, sex, education, rural/urban residence, using data from the Global Dietary Database. In 2018, mean global was 2.7 (8 oz = 248 grams) servings/week (95% UI 2.5-2.9) (range: 0.7...
Abstract The consumption of sugar-sweetened beverages (SSBs) is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). However, an updated comprehensive assessment the global burden attributable to SSBs remains scarce. Here we estimated SSB-attributable T2D CVD burdens across 184 countries in 1990 2020 globally, regionally nationally, incorporating data from Global Dietary Database, jointly stratified by age, sex, educational attainment urbanicity. In 2020, 2.2 million (95%...
Prostaglandins formed by cyclooxygenase-1 (COX-1) or COX-2 produce hyperalgesia in sensory nerve endings. To assess the relative roles of two enzymes pain processing, we compared responses COX-1- COX-2-deficient homozygous and heterozygous mice with wild-type controls hot plate stretching tests for analgesia. Preliminary observational studies determined that there were no differences gross parameters behavior between different groups. Surprisingly, on (55°C), COX-1-deficient groups showed...
Objective: This study was to investigate factors influencing the length of stay and predictors for risk readmission at an acute psychiatric inpatient unit. Method: Two comparative studies were embedded in a retrospective cross-sectional clinical file audit. A randomly selected 226 episodes admissions including 178 patients during twelve-month period reviewed. total 286 variables collected analysed. case control employed stay. cohort used readmission. Results: Logistic regression analyses...
Abstract Objective To quantify global intakes of sugar sweetened beverages (SSBs) and trends over time among children adolescents. Design Population based study. Setting Global Dietary Database. Children adolescents aged 3-19 years in 185 countries between 1990 2018, jointly stratified at subnational level by age, sex, parental education, rural or urban residence. Results In mean SSB intake was 3.6 (standardized serving=248 g (8 oz)) servings/week (1.3 (95% uncertainly interval 1.0 to 1.9)...
Abstract Despite advancements in engineered heart tissue (EHT), challenges persist achieving accurate dimensional accuracy of scaffolds and maturing human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs), a primary source functional cardiac cells. Drawing inspiration from muscle fiber arrangement, three‐dimensional (3D)‐printed multi‐layered microporous polycaprolactone (PCL) scaffold is created with interlayer angles set at 45° to replicate the precise structure native...
We wished to characterize the relationship of advanced age clinical outcomes and transcriptomic responses after severe blunt traumatic injury with hemorrhagic shock.We performed epidemiological, cytokine, analyses on a prospective, multi-center cohort 1,928 severely injured patients.We found that there was no difference in severity between aged (age ≥55, n = 533) young <55, 1395) cohorts. However, patients had more comorbidities. Advanced associated organ failure, infectious complications,...
Abstract The elderly are particularly susceptible to trauma, and their outcomes frequently dismal. Such patients often have complicated clinical courses ultimately die of infection sepsis. Recent research has revealed that although subjects increased baseline inflammation as compared with younger counterparts, the do not respond severe or injury an exaggerated inflammatory response. Initial retrospective analysis data from Glue Grant trauma database demonstrated despite a similar frequency,...
Background We aimed to systematically identify, standardise and disseminate individual-level dietary intake surveys from up 207 countries for 54 foods, beverages nutrients, including subnational intakes by age, sex, education urban/rural residence, 1980 2015. Methods Between 2008–2011 2014–2020, the Global Dietary Database (GDD) project searched assessing worldwide. prioritised nationally or subnationally representative using 24-hour recalls, Food-Frequency Questionnaires short standardised...
Abstract The regulatory mechanism of the MBW (MYB‐bHLH‐WD40) complex in safflower ( Carthamus tinctorius ) remains unclear. In present study, we show that separate overexpression genes CtbHLH41 , CtMYB63 and CtWD40‐6 Arabidopsis thaliana increased anthocyanin procyanidin contents transgenic plants partially rescued trichome reduction phenotype corresponding bhlh41 myb63 wd40‐6 single mutants. Overexpression or significantly content natural pigment hydroxysafflor yellow A (HYSA) negatively...
Importance Time on the electronic health record (EHR) is associated with burnout among physicians. Newer virtual scribe models, which enable support from either a real-time or asynchronous scribe, have potential to reduce burden of EHR and EHR-related documentation. Objective To characterize association use scribes changes in physicians’ time note order composition identify physician, response factors upon use. Design, Setting, Participants Retrospective, pre-post quality improvement study...
Abstract The Baltimore-Washington Infant Study, a case-control study of congenital heart defects in liveborn infants conducted 1981–1989, interviewed parents about wide range environmental exposures that occurred during and before the pregnancy. In period 1987–1989, questionnaire was expanded to include detailed inquiry pesticides. An analysis these latter data revealed an association maternal exposure any pesticides first trimester with transposition great arteries their (TGA; n = 66...
Previous reports indicate that growth hormone-releasing hormone (GHRH) is involved in sleep regulation. The site of action mediating the nonrapid eye movement (NREMS)-promoting effects GHRH not known, but it independent from pituitary. (0.001, 0. 01, and 0.1 nmol/kg) or a competitive antagonist (0.003, 0.3, 14 was microinjected into preoptic area, sleep-wake activity recorded for 23 hr after injection rats. elicited dose-dependent increases duration intensity NREMS compared with control...
The diverse fungal communities that colonize fruit surfaces are closely associated with development, preservation and quality control. However, the overall fungi adhering to surface inference of environmental factors still unknown. Here, we characterized signatures on apple by sequencing internal transcribed spacer 1 (ITS1) region. We collected from fruits cultivated in rural peri-urban orchards. A total 111 genera belonging 4 phyla were identified, showing remarkable diversity surface....
Animal-source foods (ASF) provide nutrition for children and adolescents' physical cognitive development. Here, we use data from the Global Dietary Database Bayesian hierarchical models to quantify global, regional national ASF intakes between 1990 2018 by age group across 185 countries, representing 93% of world's child population. Mean intake was 1.9 servings per day, 16% consuming at least three daily servings. Intake similar boys girls, but higher among urban with educated parents....