Idris Guessous
A5087112771- Nutritional Studies and Diet
- SARS-CoV-2 and COVID-19 Research
- Health disparities and outcomes
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Obesity, Physical Activity, Diet
- Long-Term Effects of COVID-19
- COVID-19 epidemiological studies
- Health, Medicine and Society
- Healthcare Systems and Practices
- SARS-CoV-2 detection and testing
- Blood Pressure and Hypertension Studies
- Vitamin D Research Studies
- Sodium Intake and Health
- Birth, Development, and Health
- Health Systems, Economic Evaluations, Quality of Life
- Nutrition, Genetics, and Disease
- Global Health Care Issues
- Global Cancer Incidence and Screening
- Data-Driven Disease Surveillance
- Urban Transport and Accessibility
- Diet and metabolism studies
- Nutrition and Health in Aging
- Consumer Attitudes and Food Labeling
- Vaccine Coverage and Hesitancy
University Hospital of Geneva
2016-2025
University of Geneva
2016-2025
Hôpital Beau-Séjour
2010-2024
Geneva College
2012-2024
École Polytechnique Fédérale de Lausanne
2018-2024
University of Lausanne
2014-2024
Générale de Santé
2022-2023
University Physicians
2023
Centre universitaire de médecine générale et santé publique, Lausanne
2020-2021
Johns Hopkins University
2015-2020
<h2>Summary</h2><h3>Background</h3> Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate consumption major foods and nutrients across 195 countries quantify their suboptimal intake NCD mortality morbidity. <h3>Methods</h3> By use a comparative assessment approach, we estimated proportion disease-specific attributable each dietary (also...
BackgroundAssessing the burden of COVID-19 on basis medically attended case numbers is suboptimal given its reliance testing strategy, changing definitions, and disease presentation. Population-based serosurveys measuring anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) antibodies provide one method for estimating infection rates monitoring progression epidemic. Here, we estimate weekly seroprevalence anti-SARS-CoV-2 in population Geneva, Switzerland, during...
CKD prevalence estimation is central to management and prevention planning at the population level. This study estimated in European adult general investigated international variation by age, sex, presence of diabetes, hypertension, obesity. We collected data from 19 general-population studies 13 countries. stages 1–5 was defined as eGFR<60 ml/min per 1.73 m 2 , calculated CKD-Epidemiology Collaboration equation, or albuminuria >30 mg/g, 3–5 . age- sex-standardized 27 Member States...
Letters8 December 2020COVID-19 Symptoms: Longitudinal Evolution and Persistence in Outpatient SettingsFREEMayssam Nehme, MD, Olivia Braillard, Gabriel Alcoba, Sigiriya Aebischer Perone, Delphine Courvoisier, PhD, François Chappuis, Idris Guessous, for the COVICARE TEAM†Mayssam MDGeneva University Hospitals, Geneva, SwitzerlandSearch more papers by this author, Hospitals Médecins Sans Frontières, International Committee of Red Cross, PhDGeneva TEAM†Search authorAuthor, Article, Disclosure...
BackgroundTobacco dependence is the leading cause of preventable death and disabilities worldwide nicotine main substance responsible for addiction to tobacco. A vaccine against was tested in a 6-month randomized, double blind phase II smoking cessation study 341 smokers with subsequent follow-up period.Methodology/Principal Findings229 subjects were randomized receive five intramuscular injections 112 placebo at monthly intervals. All received individual behavioral counseling. The safe,...
Previous studies have suggested that modern obesogenic environments accentuate the genetic risk of obesity. However, these proven controversial as to which, if any, measures environment susceptibility high body mass index (BMI).
With millions of SARS-CoV-2 infections worldwide, increasing numbers patients are coming forward with long-term clinical effects the disease lasting several weeks to months.
BackgroundDiet is a major modifiable risk factor for human health and overall consumption patterns affect planetary health. We aimed to quantify global, regional, national levels of animal-source foods (ASF) inform intervention, surveillance, policy priorities.MethodsIndividual-level dietary surveys across 185 countries conducted between 1990 2018 were identified, obtained, standardised, assessed among children adults, jointly stratified by age, sex, education level, rural versus urban...
Abstract Evidence on what people eat globally is limited in scope and rigour, especially as it relates to children adolescents. This impairs target setting investment evidence-based actions support healthy sustainable diets. Here we quantified global, regional national dietary patterns among adults, by age group, sex, education urbanicity, across 185 countries between 1990 2018, the basis of data from Global Dietary Database project. Our primary measure was Alternative Healthy Eating Index,...
The global burden of diet-attributable type 2 diabetes (T2D) is not well established. This risk assessment model estimated T2D incidence among adults attributable to direct and body weight-mediated effects 11 dietary factors in 184 countries 1990 2018. In 2018, suboptimal intake these was be 14.1 million (95% uncertainty interval (UI), 13.8-14.4 million) incident cases, representing 70.3% (68.8-71.8%) new cases globally. Largest burdens were insufficient whole-grain (26.1% (25.0-27.1%)),...
Sugar-sweetened beverages (SSBs) are associated with cardiometabolic diseases and social inequities. For most nations, recent estimates trends of intake not available; nor variation by education or urbanicity. We investigated SSB intakes among adults between 1990 2018 in 185 countries, stratified subnationally age, sex, education, rural/urban residence, using data from the Global Dietary Database. In 2018, mean global was 2.7 (8 oz = 248 grams) servings/week (95% UI 2.5-2.9) (range: 0.7...
Abstract The consumption of sugar-sweetened beverages (SSBs) is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). However, an updated comprehensive assessment the global burden attributable to SSBs remains scarce. Here we estimated SSB-attributable T2D CVD burdens across 184 countries in 1990 2020 globally, regionally nationally, incorporating data from Global Dietary Database, jointly stratified by age, sex, educational attainment urbanicity. In 2020, 2.2 million (95%...
Caffeine is the most widely consumed psychoactive substance in world and presents with wide interindividual variation metabolism. This may modify potential adverse or beneficial effects of caffeine on health. We conducted a genome-wide association study (GWAS) plasma caffeine, paraxanthine, theophylline, theobromine paraxanthine/caffeine ratio among up to 9,876 individuals European ancestry from six population-based studies. A single SNP at 6p23 (near CD83) several SNPs 7p21 AHR), 15q24...
Background Saturated fat ( SFA ), ω‐6 (n‐6) polyunsaturated PUFA and trans TFA ) influence risk of coronary heart disease CHD but attributable mortalities by country, age, sex, time are unclear. Methods Results National intakes , n‐6 were estimated using a Bayesian hierarchical model based on country‐specific dietary surveys; food availability data; and, for industry reports fats/oils packaged foods. Etiologic effects fats mortality derived from meta‐analyses prospective cohorts rates the...
<h3>Objective</h3> To assess the seasonality of cardiovascular risk factors (CVRF) in a large set population-based studies. <h3>Methods</h3> Cross-sectional data from 24 studies 15 countries, with total sample size 237 979 subjects. CVRFs included Body Mass Index (BMI) and waist circumference; systolic (SBP) diastolic (DBP) blood pressure; total, high (HDL) low (LDL) density lipoprotein cholesterol; triglycerides glucose levels. Within each study, all were adjusted for age, gender current...
Background There are no time trends in prevalence, unawareness, treatment, and control of hypertension Switzerland. The objective this study was to analyze these determine the associated factors. Methods/Findings Population-based conducted Canton Geneva, Switzerland, between 1999 2009. Blood pressure measured thrice using a standard protocol. Hypertension defined as mean systolic or diastolic blood ≥140/90 mmHg self-reported anti-hypertensive medication. Unawareness, untreated uncontrolled...
Increased renal resistive index (RRI) has been recently associated with target organ damage and cardiovascular or outcomes in patients hypertension diabetes mellitus. However, reference values the general population information on familial aggregation are largely lacking. We determined distribution of RRI, factors, heritability a population-based study. Families European ancestry were randomly selected 3 Swiss cities. Anthropometric parameters risk factors assessed. A Doppler ultrasound was...
Allelic variants in UMOD, the gene coding for uromodulin, are associated with rare tubulointerstitial kidney disorders and risk of CKD hypertension general population. The factors uromodulin excretion normal population remain largely unknown, were therefore explored this study.Urinary was measured using a validated ELISA two population-based cohorts that included more than 6500 individuals. Swiss Kidney Project on Genes Hypertension study (SKIPOGH) 817 adults (mean age±SD, 45±17 years) who...
Care of frail and dependent older adults with multiple chronic conditions is a major challenge for health care systems. The study objective was to test the efficacy providing integrated at home reduce unnecessary hospitalizations, emergency room visits, institutionalization, mortality in community dwelling adults. A prospective controlled trial conducted, real-life clinical practice settings, suburban region Geneva, Switzerland, served by two visiting nursing service centers. Three hundred...
Significance There is increasing evidence that socioeconomic conditions early in life have an impact on cognitive functioning later life. Based the large longitudinal sample from SHARE we find a clear pattern old age, related to childhood conditions: Those more affluent households show higher levels of fluid intelligence age and experience stronger decline over time executive functions. The latter phenomenon not often documented. Although modifications with aging are inevitable, course...
Increased pulse wave velocity (PWV) is a marker of aortic stiffness and an independent predictor mortality. Matrix Gla-protein (MGP) vascular calcification inhibitor that needs vitamin K to be activated. Inactive MGP, known as desphospho-uncarboxylated MGP (dp-ucMGP), can measured in plasma has been associated with various cardiovascular markers, outcomes, In this study, we hypothesized high levels dp-ucMGP are increased PWV. We recruited participants via multicenter family-based...