David De Ridder
A5012269593- COVID-19 epidemiological studies
- SARS-CoV-2 and COVID-19 Research
- Health disparities and outcomes
- Data-Driven Disease Surveillance
- COVID-19 Clinical Research Studies
- Water Treatment and Disinfection
- Pharmaceutical and Antibiotic Environmental Impacts
- Advanced Proteomics Techniques and Applications
- COVID-19 and Mental Health
- Nutritional Studies and Diet
- Bioinformatics and Genomic Networks
- SARS-CoV-2 detection and testing
- Obesity, Physical Activity, Diet
- Arsenic contamination and mitigation
- Microbial Metabolic Engineering and Bioproduction
- Global Health Care Issues
- Urban Transport and Accessibility
- Membrane Separation Technologies
- Air Quality and Health Impacts
- COVID-19 Digital Contact Tracing
- Mental Health Research Topics
- Health Systems, Economic Evaluations, Quality of Life
- Long-Term Effects of COVID-19
- Insurance, Mortality, Demography, Risk Management
- Environmental DNA in Biodiversity Studies
University Hospital of Geneva
2020-2025
World Health Organization
2025
University of Geneva
2018-2024
École Polytechnique Fédérale de Lausanne
2018-2024
University of Lausanne
2024
Evides (Netherlands)
2019-2024
Geneva College
2018-2021
Boston VA Research Institute
2019-2021
Harvard University
2017-2021
Dana-Farber Cancer Institute
2017-2021
BackgroundAssessing the burden of COVID-19 on basis medically attended case numbers is suboptimal given its reliance testing strategy, changing definitions, and disease presentation. Population-based serosurveys measuring anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) antibodies provide one method for estimating infection rates monitoring progression epidemic. Here, we estimate weekly seroprevalence anti-SARS-CoV-2 in population Geneva, Switzerland, during...
Abstract Understanding the risk of infection from household- and community-exposures transmissibility asymptomatic infections is critical to SARS-CoV-2 control. Limited previous evidence based primarily on virologic testing, which disproportionately misses mild infections. Serologic measures are more likely capture all previously infected individuals. We apply household transmission models data a cross-sectional, household-based population serosurvey 4,534 people ≥5 years 2,267 households...
Abstract Background Assessing the burden of COVID-19 based on medically-attended case counts is suboptimal given its reliance testing strategy, changing definitions and wide spectrum disease presentation. Population-based serosurveys provide one avenue for estimating infection rates monitoring progression epidemic, overcoming many these limitations. Methods Taking advantage a pool adult participants from population-representative surveys conducted in Geneva, Switzerland, we implemented study...
Abstract Background Serological assays detecting anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies are being widely deployed in studies and clinical practice. However, the duration effectiveness of protection conferred by immune response remains to be assessed population-based samples. To estimate incidence newly acquired SARS-CoV-2 infections seropositive individuals as compared seronegative controls, we conducted a retrospective longitudinal matched study....
Abstract Limited data exist on SARS-CoV-2 infection rates across sectors and occupations, hindering our ability to make rational policy, including vaccination prioritization, protect workers limit spread. Here, we present results from SEROCoV-WORK + study, a serosurvey of recruited after the first wave COVID-19 pandemic in Geneva, Switzerland. We tested (May 18—September 18, 2020) 16 32 occupations for anti-SARS-CoV-2 IgG antibodies. Of 10,513 participants, 1026 (9.8%) positive. The...
Objective: To investigate the association between socioeconomic deprivation and persistence of SARS-CoV-2 clusters. Methods: We analyzed 3,355 positive test results in state Geneva (Switzerland) from February 26 to April 30, 2020. used a spatiotemporal cluster detection algorithm monitor transmission dynamics defined spatial as time days emergence disappearance. Using measured outcome index based on neighborhood-level census data, stratified survival functions were estimated using...
Aims: To assess SARS-CoV-2 seroprevalence over the first epidemic wave in canton of Geneva, Switzerland, as well risk factors for infection and symptoms associated with IgG seropositivity. Methods: Between April June 2020, former participants a representative survey 20–74-year-old population Geneva were invited to participate study, along household members aged 5 years. Blood samples tested anti-SARS-CoV-2 immunoglobulin G. Questionnaires self-administered. We estimated Bayesian model...
Background: The post-acute impact of SARS-CoV-2 infections on chronic conditions remains poorly understood, particularly in general populations. Objectives: Our primary aim was to assess the association between and new diagnoses conditions. two secondary aims were explore geographic variations this exacerbation pre-existing Methods: This longitudinal study used data from 8086 participants Specchio-COVID-19 cohort canton Geneva, Switzerland (2021–2023). Mixed-effects logistic regressions...
Microbial removal of trace organic micropollutants (OMPs) from drinking water sources remains challenging. Nitrifying and heterotrophic bacteria in rapid sand filters (RSFs) are capable biodegrading OMPs while growing on ammonia dissolved matter (DOM). The loading patterns DOM may therefore affect microbial activities as well OMP biodegradation. So far, there is very limited information the effect substrate biodegradation at environmentally relevant concentrations (∼ 1 µg/L) RSFs. We...
Drinking water treatment plants (DWTPs) are designed to remove physical, chemical, and biological contaminants. However, until recently, the role of DWTPs in minimizing cycling antibiotic resistance determinants has got limited attention. In particular, risk selecting antibiotic-resistant bacteria (ARB) is largely overlooked chlorine-free where processes applied. Here, we combined high-throughput quantitative PCR metagenomics analyze abundance dynamics microbial communities, genes (ARGs),...
Abstract Global insights into cellular organization and function require comprehensive understanding of interactome networks. Similar to how a reference genome sequence revolutionized human genetics, map the network is critical fully understand genotype-phenotype relationships. Here we present first “all-by-all” binary map, or “HuRI”. With ~53,000 high-quality protein-protein interactions (PPIs), HuRI approximately four times larger than information curated from small-scale studies available...
The presence of organic micropollutant (OMP) in groundwater threatens drinking water quality and public health. Rapid sand filter (RSF) rely on biofilms with nitrifying methanotrophic bacteria to remove ammonia methane during production. Previous research observed the partial removal OMPs active nitrification oxidation due co-metabolic conversion OMPs. However, contribution indigenous communities from RSF has yet be fully explored. Accordingly, experiments were carried out biofilm-covered...
Abstract Background Population-based serological surveys provide a means for assessing the immunologic landscape of community, without biases related to health-seeking behaviors and testing practices typically associated with rt-PCR testing. This study assesses SARS-CoV-2 seroprevalence over first epidemic wave in Canton Geneva, Switzerland, as well biological socio-economic risk factors infection symptoms IgG seropositivity. Methods findings Between April 6 June 30, 2020, former...
Nicola Julia Aebi1,2*David De Ridder3,4Carlos Ochoa3,5Dusan Petrovic6,7Marta Fadda8Suzanne Elayan9Martin Sykora9Milo Puhan10John A. Naslund11†Stephen J. Mooney12†Oliver Gruebner10,13†
Most drinking water production plants use rapid sand filters for the removal of manganese from groundwater. The start-up on newly installed media is slow, taking several weeks till months. Reducing this period in order to prevent loss during phase has become an issue concern. In study pilot and bench scale experiments were conducted investigate mechanism, influence operational conditions (e.g. filtration rate, loading) measures that enhance capacity media. Other filter investigated with...
Rapid sand filters (RSFs) have shown potential for removing organic micropollutants (OMPs) from groundwater. However, the abiotic removal mechanisms are not well understood. In this study, we collect two field RSFs that operated in series. The primary filter abiotically removes 87.5% of salicylic acid, 81.4% paracetamol, and 80.2% benzotriazole, while secondary only paracetamol (84.6%). collected is coated by a blend iron oxides (FeOx) manganese (MnOx) combined with matter, phosphate,...
Abstract Background Obesity and obesity-related diseases represent a major public health concern. Recently, studies have substantiated the role of sugar-sweetened beverages (SSBs) consumption in development these diseases. The fine identification populations areas need for intervention remains challenging. This study investigates existence spatial clustering SSB intake frequency (SSB-IF) body mass index (BMI), their potential overlap population adults state Geneva using fine-scale geospatial...
Abstract Whether cardiovascular risk scores geographically aggregate and inform on spatial development of atherosclerotic diseases (ASCVD) remains unknown. Our aim is to determine the distribution 10-year predicted ASCVD, compare overlap resulting distributions. Using prospective data from CoLaus|PsyCoLaus cohort study (2003–2021) we computed SCORE2 in participants free ASCVD. Geographical distributions events were determined using Gi* Getis-Ord autocorrelation statistic. 6203 individuals...
BACKGROUND AND OBJECTIVES: Pandemic-related life changes may have had a deleterious impact on suicidal behaviours. Early detection of ideation and identification subgroups at increased risk could help prevent suicide, one the leading causes death among adolescents worldwide. Here, we aimed to investigate prevalence factors for in using population-based sample from Switzerland, two years into pandemic. METHODS: Between December 2021 June 2022, aged 14 17 already enrolled cohort study (State...
Introduction Since its emergence in late 2019, the SARS-CoV-2 virus has led to a global health crisis, affecting millions and reshaping societies economies worldwide. Investigating determinants of diffusion their spatiotemporal dynamics at high spatial resolution is critical for public policymaking. Methods This study analyses 194,682 georeferenced RT-PCR tests from March 2020 April 2022 canton Vaud, Switzerland. We characterized five distinct pandemic periods using metrics temporal...