Ania Wisniak
A5088304757- SARS-CoV-2 and COVID-19 Research
- Cervical Cancer and HPV Research
- COVID-19 epidemiological studies
- Global Cancer Incidence and Screening
- COVID-19 Clinical Research Studies
- Vaccine Coverage and Hesitancy
- COVID-19 and Mental Health
- SARS-CoV-2 detection and testing
- Health disparities and outcomes
- AI in cancer detection
- Long-Term Effects of COVID-19
- Endometrial and Cervical Cancer Treatments
- Genital Health and Disease
- COVID-19 and healthcare impacts
- Hepatitis B Virus Studies
- Colorectal Cancer Screening and Detection
- Viral Infections and Outbreaks Research
- Global Health Care Issues
- COVID-19 Impact on Reproduction
- Optimism, Hope, and Well-being
- Psychological Well-being and Life Satisfaction
- Psychological and Temporal Perspectives Research
- Healthcare professionals’ stress and burnout
- Influenza Virus Research Studies
- Palliative Care and End-of-Life Issues
University Hospital of Geneva
2015-2025
University of Geneva
2020-2025
University of Lausanne
2021
Hôpital Beau-Séjour
2021
BackgroundAssessing the burden of COVID-19 on basis medically attended case numbers is suboptimal given its reliance testing strategy, changing definitions, and disease presentation. Population-based serosurveys measuring anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) antibodies provide one method for estimating infection rates monitoring progression epidemic. Here, we estimate weekly seroprevalence anti-SARS-CoV-2 in population Geneva, Switzerland, during...
Abstract Objectives Seroprevalence studies to assess the spread of SARS-CoV-2 infection in general population and subgroups are key for evaluating mitigation vaccination policies understanding disease both on national level comparison with international community. Methods Corona Immunitas is a research program coordinated, population-based, seroprevalence implemented by Swiss School Public Health (SSPH+). Over 28,340 participants, randomly selected age-stratified, some regional specificities...
Abstract Understanding the risk of infection from household- and community-exposures transmissibility asymptomatic infections is critical to SARS-CoV-2 control. Limited previous evidence based primarily on virologic testing, which disproportionately misses mild infections. Serologic measures are more likely capture all previously infected individuals. We apply household transmission models data a cross-sectional, household-based population serosurvey 4,534 people ≥5 years 2,267 households...
Abstract Background Assessing the burden of COVID-19 based on medically-attended case counts is suboptimal given its reliance testing strategy, changing definitions and wide spectrum disease presentation. Population-based serosurveys provide one avenue for estimating infection rates monitoring progression epidemic, overcoming many these limitations. Methods Taking advantage a pool adult participants from population-representative surveys conducted in Geneva, Switzerland, we implemented study...
Abstract Background Serological assays detecting anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies are being widely deployed in studies and clinical practice. However, the duration effectiveness of protection conferred by immune response remains to be assessed population-based samples. To estimate incidence newly acquired SARS-CoV-2 infections seropositive individuals as compared seronegative controls, we conducted a retrospective longitudinal matched study....
The recent emergence of the SARS-CoV-2 in China has raised spectre a novel, potentially catastrophic pandemic both scientific and lay communities throughout world. In this particular context, people have been accused being excessively pessimistic regarding future consequences emerging health threat. However, consistent with previous research social psychology, large survey conducted Europe early stage COVID-19 epidemic shows that majority respondents was actually overly optimistic about risk...
Background Up-to-date seroprevalence estimates are critical to describe the SARS-CoV-2 immune landscape and guide public health decisions. Aim We estimate of anti-SARS-CoV-2 antibodies 15 months into COVID-19 pandemic 6 vaccination campaign. Methods conducted a population-based cross-sectional serosurvey between 1 June 7 July 2021, recruiting participants from age- sex-stratified random samples general population. tested for targeting spike (S) or nucleocapsid (N) proteins using Roche...
Unrealistic optimism, the underestimation of one’s risk experiencing harm, has been investigated extensively to understand better and predict behavioural responses health threats. Prior COVID-19 pandemic, a relative dearth research existed in this domain regarding epidemics, which is surprising considering that optimistic bias associated with lack engagement protective behaviours critical fighting twenty-first-century, emergent, infectious diseases. The current study addresses gap literature...
Abstract Limited data exist on SARS-CoV-2 infection rates across sectors and occupations, hindering our ability to make rational policy, including vaccination prioritization, protect workers limit spread. Here, we present results from SEROCoV-WORK + study, a serosurvey of recruited after the first wave COVID-19 pandemic in Geneva, Switzerland. We tested (May 18—September 18, 2020) 16 32 occupations for anti-SARS-CoV-2 IgG antibodies. Of 10,513 participants, 1026 (9.8%) positive. The...
Aims: To assess SARS-CoV-2 seroprevalence over the first epidemic wave in canton of Geneva, Switzerland, as well risk factors for infection and symptoms associated with IgG seropositivity. Methods: Between April June 2020, former participants a representative survey 20–74-year-old population Geneva were invited to participate study, along household members aged 5 years. Blood samples tested anti-SARS-CoV-2 immunoglobulin G. Questionnaires self-administered. We estimated Bayesian model...
Introduction The COVID-19 pandemic has affected billions of people around the world both directly through infection itself and indirectly its economic, social sanitary impact. Collecting data over time is essential for understanding disease spread, incidence COVID-19-like symptoms, level dynamics immunity, as well long-term impact pandemic. objective study was to set up a longitudinal follow-up adult participants serosurveys carried out in canton Geneva, Switzerland, during This aims at...
Binding antibody levels against SARS-CoV-2 have shown to be correlates of protection infection with pre-Omicron lineages. This has been challenged by the emergence immune-evasive variants, notably Omicron sublineages, in an evolving immune landscape high cumulative incidence and vaccination coverage. turn limits use widely available commercial high-throughput methods quantify binding antibodies as a tool monitor at population-level. Here we show that anti-Spike RBD levels, quantified...
To examine the impact of varying levels non-pharmaceutical interventions (NPIs) on COVID-19 transmission in nursing homes during first wave pandemic. Objective: The primary outcome involved exploring qualitative insights from staff and management regarding implementation NPIs. secondary was cumulative incidence PCR-confirmed cases among residents. Incident rate ratios (IRR) were calculated NPI restrictiveness. Methods: We used a mixed-methodology to identify factors that might have affected...
The COVID-19 pandemic prompted significant shifts to teleworking, raising questions about potential impacts on employee wellbeing. This study examined the association between self-reported changes teleworking frequency (relative before pandemic) and two indicators of occupational burnout: emotional exhaustion professionally diagnosed burnout. Data were derived from samples a digital cohort based in Geneva, Switzerland: one population-based, sample workers who likely mobilized early stages...
The objective of this study was to examine the impact varying levels non-pharmaceutical interventions (NPIs) on COVID-19 transmission in nursing homes during first wave pandemic. Background/Objectives: primary aim involved exploring qualitative insights from staff and management regarding implementation NPIs. secondary determine cumulative incidence PCR-confirmed cases among residents. Incident rate ratios (IRRs) were calculated NPI restrictiveness. Methods: We used a mixed methodology...
Our aim was to evaluate the feasibility and performance of smartphone digital images for detection cervical intraepithelial neoplasia grade 2 or worse (CIN2+) as an adjunct a conventional visual inspection approach with acetic acid (VIA) Lugol's iodine (VILI), in comparison by histopathologic examination.Three hundred women were primarily screened human papillomavirus (HPV) using self-collected vaginal specimens. Human papillomavirus-positive then invited VIA VILI, which interpreted (i)...
There are concerns about acute and long-term mental health effects of the COVID-19 pandemic. This study examined prevalence predictors psychological distress before, during, after a pandemic wave in Switzerland, 2021. Prevalence was estimated adults aged 35-96 years using General Health Questionnaire-12 administered June 2021 (Specchio-COVID19 cohort, N = 3965), compared to values from 2003 2006 (CoLaus|PsyCoLaus 5667). Anxiety depression were assessed February Generalised Disorder scale-2...
Abstract Background Population-based serological surveys provide a means for assessing the immunologic landscape of community, without biases related to health-seeking behaviors and testing practices typically associated with rt-PCR testing. This study assesses SARS-CoV-2 seroprevalence over first epidemic wave in Canton Geneva, Switzerland, as well biological socio-economic risk factors infection symptoms IgG seropositivity. Methods findings Between April 6 June 30, 2020, former...
Health systems around the world continue to navigate through operational challenges surfaced by coronavirus disease 2019 (COVID-19) pandemic; these have implications for access healthcare. In this study, we estimate prevalence and reasons forgoing healthcare during pandemic in Geneva, Switzerland; a country with universal mandatory private health insurance coverage.
A simple system for visual inspection with acetic acid assessment, named ABCD criteria, has been developed to increase accuracy triaging of high-risk human papillomavirus (HPV)-positive women. This study aimed determine the criteria detection histologically confirmed cervical intraepithelial neoplasia grade two or worse (CIN2+) in HPV-positive women living a low-resource setting.Prospective diagnostic accuracy.Cervical cancer screening programme based on 3T-Approach (test, triage and treat)...
This study aimed to assess acceptance of COVID-19 vaccination as well its sociodemographic and clinical determinants, 3 months after the launch programme in Geneva, Switzerland.In March 2021, an online questionnaire was proposed adults included a longitudinal cohort previous SARS-CoV-2 serosurveys carried out canton which former participants population-based health survey individuals randomly sampled from population registries, their household members. Questions were asked about acceptance,...
Objective Cervical cancer in Cameroon ranks as the second most frequent among women and leading cause of cancer-related deaths, mainly due to lack prevention. Our principal objective was explore potential barriers an human papillomavirus (HPV)-based cervical screening from a healthcare provider (HCP) perspective low-income context. Second, we aimed acceptability single-visit approach using HPV self-sampling. Settings The study took place District hospital Dschang, Cameroon. Participants...
The number of dengue cases has increased dramatically over the past 20 years and is an important concern, particularly as trends toward urbanization continue. While majority are thought to be asymptomatic, it unknown what extent these contribute transmission. A better understanding their importance would help guide control efforts. In 2019, a outbreak in La Reunion resulted more than 18,000 confirmed cases. Between October 2019 August 2020, 19 clusters were investigated south, west, east...