Carlos de Mestral
A5031808863- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Health disparities and outcomes
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
- Global Health Care Issues
- Nutrition and Health in Aging
- Long-Term Effects of COVID-19
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Global Public Health Policies and Epidemiology
- Sodium Intake and Health
- Vaccine Coverage and Hesitancy
- Chronic Disease Management Strategies
- COVID-19 epidemiological studies
- Frailty in Older Adults
- SARS-CoV-2 detection and testing
- Health Promotion and Cardiovascular Prevention
- COVID-19 and healthcare impacts
- Smoking Behavior and Cessation
- Child Welfare and Adoption
- Healthcare Policy and Management
- Diabetes Management and Research
- Cardiovascular Health and Risk Factors
- Diabetes Treatment and Management
University Hospital of Geneva
2019-2024
University of Lausanne
2018-2022
University of Geneva
2021-2022
Primary Health Care
2022
Geneva College
2022
University College London
2018-2020
Centre universitaire de médecine générale et santé publique, Lausanne
2019-2020
Institute of Social and Preventive Medicine
2016-2019
Israel Ministry of Health
2016
More than two years into the COVID-19 pandemic, most of population has developed anti-SARS-CoV-2 antibodies from infection and/or vaccination. However, public health decision-making is hindered by lack up-to-date and precise characterization immune landscape in population. Here, we estimated seroprevalence cross-variant neutralization capacity after Omicron became dominant Geneva, Switzerland.We conducted a population-based serosurvey between April 29 June 9, 2022, recruiting children adults...
The medium-term impact of the COVID-19 pandemic on wellbeing children and adolescents remains unclear. More than 2 years into pandemic, we aimed to quantify frequency determinants having been severely impacted by estimate its health-related quality life (HRQoL) mental health.
Abstract Prevalence and trends of different vegetarian diets remain unknown, with estimates varying depending on the source. Evidence suggests that are associated a more favourable cardiovascular risk profile. The present study aimed to assess prevalence types in population-based representative sample, sociodemographic characteristics participants following such association these factors. Using repeated cross-sectional surveys conducted Geneva, Switzerland, 10 797 individuals participated...
Background Up-to-date seroprevalence estimates are critical to describe the SARS-CoV-2 immune landscape and guide public health decisions. Aim We estimate of anti-SARS-CoV-2 antibodies 15 months into COVID-19 pandemic 6 vaccination campaign. Methods conducted a population-based cross-sectional serosurvey between 1 June 7 July 2021, recruiting participants from age- sex-stratified random samples general population. tested for targeting spike (S) or nucleocapsid (N) proteins using Roche...
Abstract Limited data exist on SARS-CoV-2 infection rates across sectors and occupations, hindering our ability to make rational policy, including vaccination prioritization, protect workers limit spread. Here, we present results from SEROCoV-WORK + study, a serosurvey of recruited after the first wave COVID-19 pandemic in Geneva, Switzerland. We tested (May 18—September 18, 2020) 16 32 occupations for anti-SARS-CoV-2 IgG antibodies. Of 10,513 participants, 1026 (9.8%) positive. The...
BackgroundFew studies have examined the interactions between individual socioeconomic position and neighbourhood deprivation findings so far are heterogeneous. Using a large sample of diverse cohorts, we investigated interaction effect position, assessed using education, on mortality.MethodsWe did longitudinal multicohort analysis that included six cohort participating in European LIFEPATH consortium: CoLaus (Lausanne, Switzerland), E3N (France), EPIC-Turin (Turin, Italy), EPIPorto (Porto,...
Abstract Background Socio-economic inequalities in mortality are well established, yet the contribution of intermediate risk factors that may underlie these relationships remains unclear. We evaluated role multiple modifiable underlying socio-economic-associated and quantified potential impact reducing early all-cause by hypothetically altering socio-economic factors. Methods Data were from seven cohort studies participating LIFEPATH Consortium (total n = 179 090). Using both position (SEP)...
Binding antibody levels against SARS-CoV-2 have shown to be correlates of protection infection with pre-Omicron lineages. This has been challenged by the emergence immune-evasive variants, notably Omicron sublineages, in an evolving immune landscape high cumulative incidence and vaccination coverage. turn limits use widely available commercial high-throughput methods quantify binding antibodies as a tool monitor at population-level. Here we show that anti-Spike RBD levels, quantified...
Post-COVID syndrome remains poorly studied in children and adolescents. Here, we aimed to investigate the prevalence risk factors of pediatric post-COVID a population-based sample, stratifying by serological status. Children from SEROCoV-KIDS cohort study (State Geneva, Switzerland), aged 6 months 17 years, were tested for anti-SARS-CoV-2 N antibodies (December 2021-February 2022) parents filled questionnaire on persistent symptoms their (lasting over 12 weeks) compatible with post-COVID. Of...
The COVID-19 pandemic prompted significant shifts to teleworking, raising questions about potential impacts on employee wellbeing. This study examined the association between self-reported changes teleworking frequency (relative before pandemic) and two indicators of occupational burnout: emotional exhaustion professionally diagnosed burnout. Data were derived from samples a digital cohort based in Geneva, Switzerland: one population-based, sample workers who likely mobilized early stages...
Abstract Diabetes is increasing in Switzerland, but whether its management has improved unknown. We aimed to assess diabetes prevalence, diagnosis, treatment, and control French-speaking Switzerland. Our study used cross-sectional data for years 2005–2019 from a population-based Geneva, Overall prevalence (self-reported diagnosis and/or fasting plasma glucose level ≥ 7 mmol/L), diagnosed, treated (among diagnosed participants) controlled (defined as FPG < 6.7 mmol/L among were calculated...
Socioeconomically disadvantaged people are disproportionally more likely to develop obesity and obesity-related diseases. However, it remains unclear what extent diet quality contributes socioeconomic inequalities in obesity. We aimed assess the role of association between status (SES) Data originated from national nutrition survey, a cross-sectional sample adult Swiss population (N = 1860). used education income as proxies for SES; calculated Alternate Healthy Eating Index (AHEI) measure...
Children and adolescents are highly vulnerable to the impact of sustained stressors during developmentally sensitive times. We investigated how demographic characteristics intersect with socioeconomic dimensions shape social patterning quality life mental health in children adolescents, two years into COVID-19 pandemic.We used data from prospective SEROCoV-KIDS cohort study living Geneva (Switzerland, 2022). conducted an intersectional Multilevel Analysis Individual Heterogeneity...
Health systems around the world continue to navigate through operational challenges surfaced by coronavirus disease 2019 (COVID-19) pandemic; these have implications for access healthcare. In this study, we estimate prevalence and reasons forgoing healthcare during pandemic in Geneva, Switzerland; a country with universal mandatory private health insurance coverage.
Abstract Aim To assess trends in prevalence of total and diagnosed diabetes, the probability detecting undiagnosed diabetes Swiss population. Methods The Bus Santé study is an annual cross‐sectional adults residing Geneva state, Switzerland. We included 8532 participants (51% women) from years 2005 to 2017, when fasting plasma glucose data became available. Total was defined as sum while having a previous diagnosis, level ≥7 mmol/l no diagnosis. calculated finding among without examined for...
Background: More than two years into the COVID-19 pandemic, it is generally assumed that most of population has developed anti-SARS-CoV-2 antibodies from infection and/or vaccination. However, public health decision-making hindered by lack up-to-date and precise characterization immune landscape in population. We thus aimed to estimate seroprevalence cross-variant neutralization capacity after Omicron became dominant Geneva, Switzerland. Methods: conducted a population-based serosurvey...