Allison Hodge
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Diet and metabolism studies
- Epigenetics and DNA Methylation
- Fatty Acid Research and Health
- Cancer Risks and Factors
- Birth, Development, and Health
- Folate and B Vitamins Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutrition and Health in Aging
- Colorectal Cancer Screening and Detection
- Consumer Attitudes and Food Labeling
- Health disparities and outcomes
- Diet, Metabolism, and Disease
- Cancer, Lipids, and Metabolism
- Liver Disease Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Food Security and Health in Diverse Populations
- Physical Activity and Health
- Alcohol Consumption and Health Effects
- Nutrition, Genetics, and Disease
- Antioxidant Activity and Oxidative Stress
- Vitamin D Research Studies
- Obesity and Health Practices
- Adipokines, Inflammation, and Metabolic Diseases
Cancer Council Victoria
2016-2025
The University of Melbourne
2016-2025
Helmholtz Zentrum München
2023
Center for Environmental Health
2023
University Medical Center Hamburg-Eppendorf
2023
German Center for Diabetes Research
2023
University Medical Center of the Johannes Gutenberg University Mainz
2023
German Cancer Research Center
2023
Centre International de Recherche sur le Cancer
2023
University of Minnesota
2021
The possible therapeutic impact of dietary changes on existing mental illness is largely unknown. Using a randomised controlled trial design, we aimed to investigate the efficacy improvement program for treatment major depressive episodes. 'SMILES' was 12-week, parallel-group, single blind, an adjunctive intervention in moderate severe depression. consisted seven individual nutritional consulting sessions delivered by clinical dietician. control condition comprised social support protocol...
Objective Key biological factors that influence the development of depression are modified by diet. This study examined extent to which high-prevalence mental disorders related habitual diet in 1,046 women ages 20–93 years randomly selected from population. Method A quality score was derived answers a food frequency questionnaire, and factor analysis identified dietary patterns. The 12-item General Health Questionnaire (GHQ-12) used measure psychological symptoms, structured clinical...
OBJECTIVE—To examine associations between type 2 diabetes and fiber, glycemic load (GL), dietary index (GI), fiber-rich foods. RESEARCH DESIGN AND METHODS—This was a prospective study of 36,787 men women aged 40–69 years without diabetes. For all self-reported cases at 4-year follow-up, confirmation diagnosis sought from medical practitioners. Case subjects were those who reported follow-up for whom there no evidence that they did not have Data analyzed with logistic regression, adjusting...
<h3>Importance</h3> The role of ω-3 polyunsaturated fatty acids for primary prevention coronary heart disease (CHD) remains controversial. Most prior longitudinal studies evaluated self-reported consumption rather than biomarkers. <h3>Objective</h3> To evaluate biomarkers seafood-derived eicosapentaenoic acid (EPA; 20:5ω-3), docosapentaenoic (DPA; 22:5ω-3), and docosahexaenoic (DHA; 22:6ω-3) plant-derived α-linolenic (ALA; 18:3ω-3) incident CHD. <h3>Data Sources</h3> A global consortium 19...
BackgroundThe relevance of blood lipid concentrations to long-term incidence cardiovascular disease and the lipid-lowering therapy for outcomes is unclear. We investigated risk associated with full spectrum bloodstream non-HDL cholesterol concentrations. also created an easy-to-use tool estimate probabilities a event modelled its reduction by treatment.MethodsIn this risk-evaluation risk-modelling study, we used Multinational Cardiovascular Risk Consortium data from 19 countries across...
Abstract DNA hypomethylation in certain genes is associated with tobacco exposure but it unknown whether these methylation changes translate into increased lung cancer risk. In an epigenome-wide study of from pre-diagnostic blood samples 132 case–control pairs the NOWAC cohort, we observe that most significant associations risk are for cg05575921 AHRR (OR 1 s.d.=0.37, 95% CI: 0.31–0.54, P -value=3.3 × 10 −11 ) and cg03636183 F2RL3 s.d.=0.40, 0.31–0.56, -value=3.9 −10 ), previously shown to...
Abstract Low socioeconomic status (SES) is associated with earlier onset of age-related chronic conditions and reduced life-expectancy, but the underlying biomolecular mechanisms remain unclear. Evidence DNA-methylation differences by SES suggests a possible association epigenetic age acceleration (AA). We investigated AA in more than 5,000 individuals belonging to three independent prospective cohorts from Italy, Australia, Ireland. was greater (β = 0.99 years; 95% CI 0.39,1.59; p 0.002;...
The association between aging and cancer is complex. Recent studies have developed measures of biological based on DNA methylation called them "age acceleration." We aimed to assess the associations age acceleration with risk survival from seven common cancers. Seven case-control colorectal, gastric, kidney, lung, prostate urothelial B-cell lymphoma nested in Melbourne Collaborative Cohort Study were conducted. Cancer cases, vital status cause death ascertained through linkage registries....
Abstract The health effects of omega-3 fatty acids have been controversial. Here we report the results a de novo pooled analysis conducted with data from 17 prospective cohort studies examining associations between blood acid levels and risk for all-cause mortality. Over median 16 years follow-up, 15,720 deaths occurred among 42,466 individuals. We found that, after multivariable adjustment relevant factors, death all causes was significantly lower (by 15–18%, at least p < 0.003) in...
Differences in health status by socioeconomic position (SEP) tend to be more evident at older ages, suggesting the involvement of a biological mechanism responsive accumulation deleterious exposures across lifespan. DNA methylation (DNAm) has been proposed as biomarker aging that conserves memory endogenous and exogenous stress during life.We examined association education level, an indicator SEP, lifestyle-related variables with four biomarkers age-dependent DNAm dysregulation: total number...
<h3>Abstract</h3> <b>Objective</b>: To measure serum leptin concentrations in the Polynesian population of Western Samoa and to examine epidemiological associations with anthropometric, demographic, behavioural, metabolic factors this a high prevalence obesity non-insulin dependent diabetes mellitus. <b>Design</b>: Cross sectional study, concentration being measured subgroup based sample. <b>Subjects</b>: 240 men women aged 28–74 years were selected cover full range age, body mass index,...
Abstract Background: Red meat and processed consumption have been associated with increased risk of colorectal cancer in some, but not all, relevant cohort studies. Evidence on the relationship between poultry fish is inconsistent. Methods: We conducted a prospective study 37,112 residents Melbourne, Australia recruited from 1990 to 1994. Diet was measured food frequency questionnaire. categorized fresh red meat, chicken, into approximate quartiles. Adenocarcinomas colon or rectum were...
DNA methylation changes are associated with cigarette smoking. We used the Illumina Infinium HumanMethylation450 array to determine whether in from pre-diagnostic, peripheral blood samples is lung cancer risk. a case-control study nested within EPIC-Italy cohort and MCCS as discovery sets (a total of 552 pairs). validated top signals 429 pairs another 3 studies. identified six CpGs for which hypomethylation was risk: cg05575921 AHRR gene (p-value