A5013763024- Parasites and Host Interactions
- Criminal Justice and Corrections Analysis
- COVID-19 Clinical Research Studies
- HIV, Drug Use, Sexual Risk
- SARS-CoV-2 and COVID-19 Research
- Migration, Health and Trauma
- Health, Medicine and Society
- Healthcare Systems and Practices
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis B Virus Studies
- COVID-19 epidemiological studies
- Homelessness and Social Issues
- Hepatitis C virus research
- SARS-CoV-2 detection and testing
- Virology and Viral Diseases
- Vaccine Coverage and Hesitancy
- Parasitic Infections and Diagnostics
- Healthcare Decision-Making and Restraints
- Torture, Ethics, and Law
- Travel-related health issues
- Syphilis Diagnosis and Treatment
- COVID-19 and Mental Health
- Global Maternal and Child Health
- COVID-19 and healthcare impacts
- Suicide and Self-Harm Studies
University Hospital of Geneva
2015-2025
University of Geneva
2013-2023
Geneva College
2010-2022
Federal Office of Public Health
2021
Universidad Peruana Cayetano Heredia
2008
Hôpital Beau-Séjour
2007
BackgroundAssessing the burden of COVID-19 on basis medically attended case numbers is suboptimal given its reliance testing strategy, changing definitions, and disease presentation. Population-based serosurveys measuring anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) antibodies provide one method for estimating infection rates monitoring progression epidemic. Here, we estimate weekly seroprevalence anti-SARS-CoV-2 in population Geneva, Switzerland, during...
Nifurtimox has been used to treat Chagas disease for 40 years, but tolerance and safety data in adults are scarce. We aimed evaluate nifurtimox a cohort of Trypanosoma cruzi-infected adult patients country nonendemicity.This observational study included all consecutive who were given diagnosis T. cruzi infection from June through December 2008. Eligible received at 10 mg/kg/day 60 days, with regular medical biological follow-up. Adverse events (AEs) recorded according Common Terminology...
Abstract Understanding the risk of infection from household- and community-exposures transmissibility asymptomatic infections is critical to SARS-CoV-2 control. Limited previous evidence based primarily on virologic testing, which disproportionately misses mild infections. Serologic measures are more likely capture all previously infected individuals. We apply household transmission models data a cross-sectional, household-based population serosurvey 4,534 people ≥5 years 2,267 households...
Abstract Background Assessing the burden of COVID-19 based on medically-attended case counts is suboptimal given its reliance testing strategy, changing definitions and wide spectrum disease presentation. Population-based serosurveys provide one avenue for estimating infection rates monitoring progression epidemic, overcoming many these limitations. Methods Taking advantage a pool adult participants from population-representative surveys conducted in Geneva, Switzerland, we implemented study...
Abstract Background Serological assays detecting anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies are being widely deployed in studies and clinical practice. However, the duration effectiveness of protection conferred by immune response remains to be assessed population-based samples. To estimate incidence newly acquired SARS-CoV-2 infections seropositive individuals as compared seronegative controls, we conducted a retrospective longitudinal matched study....
Background Migration of Latin Americans to the USA, Canada and Europe has modified Chagas disease distribution, but data on imported cases risks local transmission remain scarce. We assessed prevalence risk factors for disease, staged evaluated attitudes towards blood transfusion organ transplant among American migrants in Geneva, Switzerland. Methodology/Principal Findings This cross-sectional study included all consecutive seeking medical care at a primary facility or attending two Latino...
Words matter when describing people involved in the criminal justice system because language can have a significant impact upon health, wellbeing, and access to health information services. However, terminology used policies, programs, research publications is often derogatory, stigmatizing, dehumanizing. In response, experts from Europe, United States, Australia recommend that healthcare professionals, researchers, policy makers working with detention follow key principles foster...
Strongyloidiasis is a disease caused by an infection with soil-transmitted helminth that affects, according to largely varying estimates, between 30 million and 370 people worldwide [1,2]. Not officially listed as neglected tropical (NTD), strongyloidiasis stands out particularly overlooked [3]. Indeed, there paucity of research public health efforts pertaining strongyloidiasis. Hence, clinical, diagnostic, epidemiologic, treatment, control aspects are not adequately addressed allow for...
Abstract Limited data exist on SARS-CoV-2 infection rates across sectors and occupations, hindering our ability to make rational policy, including vaccination prioritization, protect workers limit spread. Here, we present results from SEROCoV-WORK + study, a serosurvey of recruited after the first wave COVID-19 pandemic in Geneva, Switzerland. We tested (May 18—September 18, 2020) 16 32 occupations for anti-SARS-CoV-2 IgG antibodies. Of 10,513 participants, 1026 (9.8%) positive. The...
During the first wave of Covid-19 pandemic, access to health care was limited, and patients encountered important delays for scheduled appointments care. Empirical data relying on patients' reports forgoing are scarce. This study investigated Covid-19-related self-reports in a sample vulnerable outpatients Geneva, Switzerland. We collected from 1167 adult outpatients, including clinically (with chronic diseases), geriatric (involved network people aged 60 or older), socially migrant program...
Background Strongyloidiasis can be fatal in immunocompromised patients, but few epidemiological studies investigated the burden of this neglected tropical disease among these populations, particularly low- and middle-income countries such as Bolivia. This study aimed to fill gap by estimating prevalence rate risk factors associated with strongyloidiasis patients at high complications Methods A cross-sectional was carried out Santa Cruz (elevation 400 meters, climate) Cochabamba 2,500...
People with psychiatric and substance use disorders are more likely to smoke less quit than smokers in the general population. We evaluated efficacy of e-cigarettes for abstinence from tobacco smoking people problems. analyzed data collected larger 'Efficacy, Safety, Toxicology ENDS as an Aid Smoking Cessation' (ESTxENDS) trial (n=1246): intervention group received e-liquids, plus standard-of-care cessation counseling (SOC) 6 months; control SOC a voucher. The primary outcome was...
Little is known about the health status of prisoners in Switzerland. The aim this study was to provide a detailed description problems presented by detainees Switzerland's largest remand prison.In retrospective cross-sectional we reviewed records all leaving prison 2007. were coded using International Classification for Primary Care (ICPC-2). Analyses descriptive, stratified gender.A total 2195 reviewed. Mean age 29.5 years (SD 9.5); 95% male; 87.8% migrants. length stay 80 days 160)....
Abstract Background Strongyloidiasis is an infectious disease that can be fatal in immunocompromised patients. Patients with end-stage renal failure who are on dialysis have a considerably weakened immune system, and organ transplantation major risk factor for severe strongyloidiasis. Knowledge of the local epidemiology tropical subtropical areas essential prerequisite designing appropriate strategy to prevent this potentially lethal complication. In study, we aimed estimate prevalence...
Self-harm is a common issue in detention and includes both suicidal non-suicidal behaviours. Beyond well-known individual risk factors, institutional factors such as overcrowding (i.e., when the prison population exceeds its capacity) turnover rate at which renewed), may also increase of self-harm. However, these are understudied or previous studies reported inconsistent findings. This study investigated association self-harm with largest pre-trial Swiss Geneva. Data were collected yearly...
Incarcerated people carry a high burden of infection, including blood-borne diseases (BBDs). It is also known that one million contract sexually transmitted infection (STI) every day worldwide, which represents global public health challenge. However, data regarding the prevalence STIs and risk factors among incarcerated populations are lacking. The objective this study was to determine associated BBDs detainees in largest pre-trial prison Switzerland.In cross-sectional conducted at...
Violence is common in prison and its individual risk factors are well documented. However, there a mixed evidence on the relationship between violence institutional factors, such as overcrowding turnover, recent research suggested that these may not be important or relevant. This study investigated association Swiss pre-trial 2013 2018. Measures included (assaults requiring immediate medical attention) annual turnover rates. Using meta-regression, results showed was higher when increased....
We report the fatal case of acute melioidosis in a patient returning from Martinique with fever November 2010. Gram-negative rods were isolated blood culture and Burkholderia pseudomallei identified within 24 hours after first medical contact. The died two days admission to hospital despite intravenous therapy high doses imipenem/cilastatin intensive care. Clinicians seeing travellers subtropics or tropics severe pneumonia septicaemia should consider possibility melioidosis.
Hepatitis B virus (HBV) is a major health concern in prison, but data are scarce European prisons. This study aims to measure the prevalence of HBV infection, risk factors, awareness about and knowledge among inmates Switzerland's largest pre-trial prison.Serological blood tests (HBsAg, anti-HBs, anti-HBc) standardized socio-demographic sexual survey were offered consenting prisoners 2009 2011. was assessed using questionnaire participants recruited 2009.A total 273 male included (116...
This article considers health and human rights implications for people deprived of liberty during the COVID-19 crisis. The risks incarceration individual community health, particularly in overcrowded underresourced prisons detention centers, are well known, but with pandemic have become a public emergency. Physical distancing is hardly manageable, protective means poor or lacking. Emergency releases been shown to be feasible terms safety lack sustainability reducing number living detention,...
Strongyloides stercoralis, causative agent of a neglected tropical disease, is soil-transmitted helminth which may cause lifelong persisting infection due to continuous autoinfection. In the case immunosuppression, life-threatening hyperinfection and disseminated strongyloidiasis can develop. We propose pragmatic screening algorithm for latent based on epidemiologic exposure immunosuppression status that be applied any kind immunosuppressive therapy. The allows diagnosis with optimal...