A5054597474- Smoking Behavior and Cessation
- Colorectal Cancer Screening and Detection
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Systems and Practices
- Lipoproteins and Cardiovascular Health
- Cannabis and Cannabinoid Research
- Obesity, Physical Activity, Diet
- Clinical practice guidelines implementation
- Cardiovascular Health and Risk Factors
- Acute Myocardial Infarction Research
- Health Promotion and Cardiovascular Prevention
- Gastric Cancer Management and Outcomes
- Health, Medicine and Society
- Health and Medical Studies
- Cardiac Health and Mental Health
- Global Cancer Incidence and Screening
- Patient-Provider Communication in Healthcare
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Disease and Adiposity
- Genetic factors in colorectal cancer
- Alcohol Consumption and Health Effects
- Sleep and related disorders
- Cardiac Imaging and Diagnostics
- Substance Abuse Treatment and Outcomes
- Sleep and Wakefulness Research
University of Bern
2016-2025
University of Lausanne
2016-2025
Centre universitaire de médecine générale et santé publique, Lausanne
2019-2025
University of Zurich
2016-2024
University Hospital of Bern
2016-2024
Primary Health Care
2024
University Hospital of Lausanne
2010-2024
University of Basel
2024
Sorbonne Université
2024
University of Fribourg
2024
This study analyzed the content of smoke from heat-not-burn tobacco cigarettes compared with that conventional to determine whether similar toxic compounds are released in cigarette smoke.
Abstract Update to this article In October 2022, three years after the initial publication of guideline, first trial effect colonoscopy screening was published. The implications new evidence for current recommendations were evaluated by guideline panel in January 2023. judged that did not alter recommendations, and therefore an update following needed (see table 2 details). Clinical question Recent 15-year updates sigmoidoscopy trials provide on effectiveness colorectal cancer screening....
Electronic nicotine-delivery systems - also called e-cigarettes are used by some tobacco smokers to assist with quitting. Evidence regarding the efficacy and safety of these is needed.
We aimed to assess the prevalence and management of clinical familial hypercholesterolaemia (FH) among patients with acute coronary syndrome (ACS). studied 4778 ACS from a multi-centre cohort study in Switzerland. Based on personal history premature cardiovascular disease LDL-cholesterol levels, two validated algorithms for diagnosis FH were used: Dutch Lipid Clinic Network algorithm possible (score 3–5 points) or probable/definite (>5 points), Simon Broome Register FH. At time...
Proprotein convertase subtilisin kexin 9 (PCSK9) is an emerging target for the treatment of hypercholesterolaemia, but clinical utility PCSK9 levels to guide unknown. We aimed prospectively assess prognostic value plasma in patients with acute coronary syndromes (ACS). Plasma were measured 2030 ACS undergoing angiography a Swiss prospective cohort. At 1 year, association between tertiles and all-cause death was assessed adjusting Global Registry Acute Coronary Events (GRACE) variables, as...
Marijuana use is increasingly common in the United States. It unclear whether it has long-term effects on memory and other domains of cognitive function.
Patients with heterozygous familial hypercholesterolemia (FH) and coronary heart disease have high mortality rates. However, in an era of high-dose statin prescription after acute syndrome (ACS), the risk recurrent cardiovascular events associated FH might be mitigated. We compared event rates between patients without ACS.We studied 4534 ACS enrolled a multicenter, prospective cohort study Switzerland 2009 2013 who were individually screened for on basis clinical criteria according to 3...
Background— The coronary artery calcium (CAC) score predicts future heart disease (CHD) events and could be used to guide primary prevention interventions, but CAC measurement has costs exposes patients low-dose radiation. Methods Results— We estimated the cost-effectiveness of measuring prescribing statin therapy based on resulting under a range assumptions using an established model enhanced with distribution risk estimates from Multi-Ethnic Study Atherosclerosis. Ten years treatment for...
To investigate the effects of marijuana in development incident cardiovascular and cerebrovascular outcomes.
Objective Guidelines for thyroid function evaluation recommend testing TSH first, then assessing fT4 only if is out of the reference range (two-step), but many clinicians initially request both and (one-step). Given limitations previous studies, we aimed to compare two-step with one-step approach in an unselected community-dwelling study population, develop a prediction score based on clinical parameters that could identify at-risk patients dysfunction. Design Cross-sectional analysis...
Abstract Cigarette smoking has been associated with dementia and dementia-related brain changes, notably gray matter (GM) volume atrophy. These associations are thought to reflect the co-morbidity of vascular, respiratory, substance use/psychological conditions. However, extent localization smoking-GM relationship degree which factors influence this remain unclear. In Coronary Artery Risk Development in Young Adults CARDIA cohort ( n = 698; 52% women; 40% black participants; age 50.3 (SD...
Abstract Background and purpose Insomnia is a common debilitating disorder that frequently associated with important consequences for physical health well‐being. Methods An international expert group considered the current state of knowledge based on most relevant publications in previous 5 years, discussed challenges field insomnia identified future priorities. Results The association trajectories subsequent quality life, mortality should be investigated large populations. Prospective...
Background Evidence regarding short-term effects of electronic nicotine delivery systems (ENDS) and tobacco smoke on lung ventilation perfusion is limited. Purpose To examine the immediate effect ENDS exposure by functional MRI function tests. Materials Methods This prospective observational pilot study was conducted from November 2019 to September 2021 (substudy randomized controlled trial NCT03589989). Included were 44 healthy adult participants (10 control participants, nine former...
<h3>Objective</h3> To assess safety up to 1 year of follow-up associated with prasugrel and clopidogrel use in a prospective cohort patients acute coronary syndromes (ACS). <h3>Methods</h3> Between 2009 2012, 2286 invasively managed for ACS were enrolled the multicentre Swiss Bleeding Cohort, among whom 2148 received either or according current guidelines. Patients ST-elevation myocardial infarction (STEMI) preferentially prasugrel, while those non-STEMI, history stroke transient ischaemic...
Unlike tobacco, the effect of marijuana smoke on subclinical atherosclerosis, a surrogate measure for cardiovascular disease, is not known. This study aimed to determine association between lifetime exposure and measures atherosclerosis in mid-life.We used data from US-based Coronary Artery Risk Development Young Adults (CARDIA) study, cohort black white men women aged 18-30 years at baseline 1985-86, with up seven follow-up examinations over 25 years. A total 3498 participants CARDIA were...
Abstract We investigated the prevalence and treatment of patients with chronic insomnia presenting to Swiss primary care physicians (PCPs) part “Sentinella”, a nationwide practice‐based research network. Each PCP consecutively asked 40 if they had sleep complaints, documented frequency, duration, comorbidities, reported ongoing treatment. analysed data 63% (83/132) PCPs invited. The 76% (2,432/3,216) included about their (51% female); 31% (761/2,432) these symptoms; 36% (875/2,432) current...
Introduction: Colorectal cancer (CRC) screening relies primarily on colonoscopy and fecal immunochemical testing (FIT). Aligning utilization of these options with individual CRC risk may optimize benefit lower risks, burden, societal costs. We studied the effect communicating personalized corresponding recommendations risk-appropriate uptake in an organized setting. Methods: Randomized controlled trial among residents aged 50-69 years not yet invited for Vaud, Switzerland. The intervention...
The authors have each completed and submitted an ICMJE form for Disclosure of Potential Conflicts Interest. declare that they no competing interests, financial or otherwise, related to the current work. R. Auer, M. L. Haller, A. Schoeni report received funding from Swiss National Science Foundation (SNSF) [grant number IICT_33IC30_173552], Tobacco Prevention Fund (TPF) 19.017477], Cancer Research (SCR) [KFS4744-02-2019], Lunge Zürich.
People with psychiatric and substance use disorders are more likely to smoke less quit than smokers in the general population. We evaluated efficacy of e-cigarettes for abstinence from tobacco smoking people problems. analyzed data collected larger 'Efficacy, Safety, Toxicology ENDS as an Aid Smoking Cessation' (ESTxENDS) trial (n=1246): intervention group received e-liquids, plus standard-of-care cessation counseling (SOC) 6 months; control SOC a voucher. The primary outcome was...