A5081011802- Pesticide Exposure and Toxicity
- Effects and risks of endocrine disrupting chemicals
- Carcinogens and Genotoxicity Assessment
- Contact Dermatitis and Allergies
- Smoking Behavior and Cessation
- Advancements in Transdermal Drug Delivery
- Pesticide and Herbicide Environmental Studies
- Toxic Organic Pollutants Impact
- Pesticide Residue Analysis and Safety
- Air Quality and Health Impacts
- Insect and Pesticide Research
- Cannabis and Cannabinoid Research
- Agriculture and Rural Development Research
- Radioactivity and Radon Measurements
- Chemistry and Chemical Engineering
- Obesity, Physical Activity, Diet
- Forensic Toxicology and Drug Analysis
- Agricultural safety and regulations
- Radiation Dose and Imaging
- Allergic Rhinitis and Sensitization
- Agriculture and Farm Safety
- Radioactive contamination and transfer
- Coffee research and impacts
- Bacterial biofilms and quorum sensing
- Microplastics and Plastic Pollution
University of Lausanne
2016-2025
Centre universitaire de médecine générale et santé publique, Lausanne
2019-2025
Institute for Work and Health
2011-2025
Zurich University of Teacher Education
2025
Swiss Centre for Applied Human Toxicology
2024-2025
Swiss School of Public Health
2025
University of Fribourg
2024
University of Basel
2024
University of Zurich
2024
Sorbonne Université
2024
This study analyzed the content of smoke from heat-not-burn tobacco cigarettes compared with that conventional to determine whether similar toxic compounds are released in cigarette smoke.
Electronic nicotine-delivery systems - also called e-cigarettes are used by some tobacco smokers to assist with quitting. Evidence regarding the efficacy and safety of these is needed.
Personal protection equipment (PPE) holds a privileged position in safety interventions many countries, despite the fact that they should only be used as last resort. This is even more paradoxical because concerns have arisen to their actual effectiveness under working conditions and ability provide attributed them by certain occupational strategies marketing authorisation procedures. Are these justified? article intended an update on what we know of issue based critical analysis literature...
Abstract Therapeutic cannabis administration is increasingly used in Western countries due to its positive role several pathologies. Dronabinol or tetrahydrocannabinol (THC) pills, ethanolic tinctures, oromucosal sprays table vaporizing devices are available but other cannabinoids forms can be used. Inspired by the illegal practice of dabbing butane hashish oil (BHO), from were extracted with gas and resulting concentrate (BHO) was atomized specific devices. The efficiency “cannavaping,”...
Population studies reveal widespread exposure to phthalates. Understanding their absorption, distribution, metabolism, and excretion is vital reduce exposure. However, data on skin absorption remain limited. We thus aim characterize the permeation of three phthalates in a mixture, neat or emulsion; di(2-ethylhexyl) phthalate (d4-DEHP), dibutyl (d4-DBP), diethyl (d4-DEP), by comparing vitro human (800 µm) (24 hours) results using flow-through diffusion cells with urine obtained from...
The authors have each completed and submitted an ICMJE form for Disclosure of Potential Conflicts Interest. declare that they no competing interests, financial or otherwise, related to the current work. R. Auer, M. L. Haller, A. Schoeni report received funding from Swiss National Science Foundation (SNSF) [grant number IICT_33IC30_173552], Tobacco Prevention Fund (TPF) 19.017477], Cancer Research (SCR) [KFS4744-02-2019], Lunge Zürich.
People with psychiatric and substance use disorders are more likely to smoke less quit than smokers in the general population. We evaluated efficacy of e-cigarettes for abstinence from tobacco smoking people problems. analyzed data collected larger 'Efficacy, Safety, Toxicology ENDS as an Aid Smoking Cessation' (ESTxENDS) trial (n=1246): intervention group received e-liquids, plus standard-of-care cessation counseling (SOC) 6 months; control SOC a voucher. The primary outcome was...
Abstract Incidence of allergic contact dermatitis (ACD) is rising worldwide as a consequence raising chemical exposure, especially from biocides present in common water-based products such cosmetics and household products. Understanding the biological processes involved skin sensitization crucial to mitigating ACD. Migration Langerhans cells basal lamina key step sensitization. Animal testing for has been largely replaced by alternative vitro methods due ethical concerns. This study presents...
In this study, silver/copper (Ag/Cu)-coated catheters were investigated for their efficacy in preventing methicillin-resistant Staphylococcus aureus (MRSA) infection vitro and vivo Ag Cu sputtered (67/33% atomic ratio) on polyurethane by direct-current magnetron sputtering. vitro, Ag/Cu-coated uncoated immersed phosphate-buffered saline (PBS) or rat plasma exposed to MRSA ATCC 43300 at 10(4) 10(8) CFU/ml. vivo, placed the jugular vein of rats. Directly after, (10(7) CFU/ml) was inoculated...
In December 2020, high soil concentrations of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) were discovered across large parts Lausanne, Switzerland. Concentrations reached up to 640 ng TEQWHO-2005/kg dry weight. The most likely source was a former municipal waste incinerator. A three-step, multidisciplinary approach human health risk assessment conducted determine the potential population exposure PCDD/Fs identify appropriate preventive measures. First, scenarios...
Oxidative stress can contribute to the development of diseases, and may originate from exposures toxicants commonly found in air pollution cigarette smoke such as polycyclic aromatic hydrocarbons (PAHs) volatile organic compounds (VOCs). Yet, associations between these oxidative biomarkers are poorly characterized. We report here novel 14 exposure PAHs VOCs, two biomarkers; 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) 8-isoprostaglandin F2α (8-isoprostane) urine obtained smokers...
ABSTRACT The time courses of key biomarkers exposure to captan and folpet was assessed in accessible biological matrices orally exposed volunteers. Ten volunteers ingested 1 mg kg −1 body weight or folpet. Blood samples were withdrawn at fixed periods over the 72 h following ingestion complete urine voids collected 96 post‐dosing. tetrahydrophthalimide (THPI) metabolite along with phthalimide (PI) phthalic acid metabolites then quantified these samples. Plasma levels THPI PI increased...
Pesticide exposure is a suspected risk factor for childhood cancer. We investigated the of developing cancer in relation to parental occupational pesticides Switzerland period 1990-2015.From nationwide census-based cohort study Switzerland, we included children aged < 16 years at national censuses 1990 and 2000 followed them until 2015. extracted occupations reported census closest birth year child estimated using job matrix. Cox proportional hazards models, adjusted potential confounders,...
210Po is a radioactive component of conventional cigarette tobacco smoke and recognized carcinogen. Despite the expanding market heated products, no data are available on activity in IQOS Heets cigarette. We determined mainstream thirteen brands Swiss using smoking machine compared results to measured system. In addition, we 210Pb loss heating after uniform from 50 600 °C for several cigarettes. 13.6 ± 4.1% was found (7% 210Pb). This dropped 1.8 0.3% Heets. Conversely, when uniformly at 330...