A5087378968- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- COVID-19 and Mental Health
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Emergency and Acute Care Studies
- Respiratory viral infections research
- Clinical practice guidelines implementation
- Clinical Reasoning and Diagnostic Skills
- Electronic Health Records Systems
- Patient Satisfaction in Healthcare
- COVID-19 and healthcare impacts
- COVID-19 epidemiological studies
- Healthcare Systems and Practices
- Healthcare Systems and Technology
- Food Allergy and Anaphylaxis Research
- Phonocardiography and Auscultation Techniques
- Biosensors and Analytical Detection
- Trauma and Emergency Care Studies
- Medical Coding and Health Information
- Family and Patient Care in Intensive Care Units
- Pharmaceutical Practices and Patient Outcomes
- Radiology practices and education
- Mosquito-borne diseases and control
University Hospital of Geneva
2018-2024
University of Geneva
2022-2024
Hôpital Beau-Séjour
2011-2024
Geneva College
2020-2021
Foederatio Medicorum Helveticorum
2015
Kohler (New Zealand)
2015
Schweizerische Ärztegesellschaft für Psycholytische Therapie
2015
Post-COVID condition is prevalent in 10-35% of cases outpatient settings, however a stratification the duration and severity symptoms still lacking, adding to complexity heterogeneity definition post-COVID its oucomes. In addition, potential impacts longer disease are not yet clear, along with which risk factors associated chronification beyond initial 12 weeks. this study, follow-up was conducted at 7 15 months after testing SARS-CoV-2 center Geneva University Hospitals. The defined as...
Persistent symptoms of SARS-CoV-2 are prevalent weeks to months following the infection. To date, it is difficult disentangle direct from indirect effects SARS-CoV-2, including lockdown, social, and economic factors.The study aims characterize prevalence symptoms, functional capacity, quality life at 12 in outpatient symptomatic individuals tested positive for compared negative.From 23 April 27 July 2021, Geneva University Hospitals were followed up after their test date.At months, out 1447...
Post-coronovirus disease (COVID) symptoms can persist several months after severe acute respiratory syndrome coronavirus 2 infection. Little is known, however, about the prevalence of post-COVID condition following infections from Omicron variants and how this varies according to vaccination status. This study evaluates functional impairment 12 weeks an infection by (BA.1 BA.2) compared with negative controls tested during same period.Outpatient individuals who positive or for COVID-19...
Abstract Background The optimal duration of antibiotic therapy for treating orthopaedic implant infections after surgical drainage and complete removal is unknown. Methods This was a single-centre, unblinded, prospective trial randomizing (1:1) eligible patients to either 4 or 6 weeks systemic, pathogen-targeted therapy. Clinical registration number: ClinicalTrials.gov (NCT0362209). Results We analysed 123 (62 in the week arm 61 arm) ITT analysis. patients’ median age 64 years, 75 (61%) were...
Patient satisfaction has become an increasingly important element in a service-oriented healthcare market. Although is influenced by many factors, the waiting time to be seen medical staff been shown one of key criteria. However, not objective experience and several factors can influence its perception.We conducted questionnaire-based, cross-sectional study among patients attending emergency unit Swiss university hospital order explore influencing wait perception.A total 509 participated...
During the first wave of Covid-19 pandemic, access to health care was limited, and patients encountered important delays for scheduled appointments care. Empirical data relying on patients' reports forgoing are scarce. This study investigated Covid-19-related self-reports in a sample vulnerable outpatients Geneva, Switzerland. We collected from 1167 adult outpatients, including clinically (with chronic diseases), geriatric (involved network people aged 60 or older), socially migrant program...
ABSTRACT Several SARS-CoV-2 variants of concern (VOC) are spreading rapidly in different regions the world. The underlying mechanisms behind their transmission advantage remain unclear. We measured viral load 950 individuals and found that infections with variant Alpha exhibit a higher longer shedding compared to non-VOC. then used model analyze spread Geneva, Switzerland, Beta South Africa. estimated is either associated 37% (95% compatibility interval, CI: 25–63%) increase transmissibility...
Abstract Objectives To validate the diagnostic accuracy of a Euroimmun SARS-CoV-2 IgG and IgA immunoassay for COVID-19. Methods In this unmatched (1:1) case-control validation study, we used sera 181 laboratory-confirmed cases 176 controls collected before emergence. Diagnostic was assessed against whole spike protein-based recombinant immunofluorescence assay (rIFA) by receiver operating characteristic (ROC) analyses. Discrepant between ELISA rIFA were further tested pseudo-neutralization...
SARS-CoV-2 viral load (VL) can serve as a correlate for infectious virus presence and transmission. Viral shedding kinetics over the first week of illness symptomatic children (n = 279), adolescents 639), adults 7109) show VLs compatible with presence, slightly lower VL in than adults.
Lung auscultation is fundamental to the clinical diagnosis of respiratory disease. However, a subjective practice and interpretations vary widely between users. The digitization acquisition interpretation particularly promising strategy for diagnosing monitoring infectious diseases such as Coronavirus-19 disease (COVID-19) where automated analyses could help decentralise care better inform decision-making in telemedicine. This protocol describes standardised collection lung auscultations...
Abstract Experts have warned against the pandemic burden on healthcare workers early on, however little is known about evolution of this with time, in addition to long-term effects post-COVID symptoms workers. Staff at Geneva University Hospitals Switzerland had an online follow-up July and December 2021, their physical mental health, quality life functional capacity using validated scales. Descriptive analyses compared prevalence symptoms, impairment SARS-CoV-2 positive negative individuals...
Automated medical history-taking devices (AMHTDs) are emerging tools with the potential to increase quality of consultations by providing physicians an exhaustive, high-quality, standardized anamnesis and differential diagnosis.This study aimed assess effectiveness AMHTD obtain accurate diagnosis in outpatient service.We conducted a pilot randomized controlled trial involving 59 patients presenting emergency unit suffering from various conditions affecting limbs, back, chest wall. Resident...
Background Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2), the novel coronavirus that causes disease (COVID-19), is creating an unprecedented burden on health care systems across world due to its high rate of pneumonia-related hospitalizations. This study presents recommendations for outpatient management moderate SARS-CoV-2 pneumonia implemented at Geneva University Hospital, Switzerland, from April 4 June 30, 2020 and evaluated impact these patient safety, satisfaction, overall...
Purpose: To assess the diagnostic performances of five automated anti-SARS-CoV-2 immunoassays, Epitope (N), Diasorin (S1/S2), Euroimmun (S1), Roche N and S (S-RBD), to provide a testing strategy based on pre-test probability. Methods: We assessed receiver operating characteristic (ROC) areas under curve (AUC) values, along with sensitivity, specificity, positive predictive values (PPVs), negative (NPVs), each assay using validation sample set 172 COVID-19 sera 185 controls against validated...
Objectives To develop and validate a rule-out prediction model for the risk of hospitalisation among patients with SARS-CoV-2 infection in ambulatory setting to derive simple score determine outpatient follow-up. Design Prospective cohort study. Setting Swiss university hospital. Participants 1459 individuals positive result between 2 March 23 April 2020. Methods We applied rule 10 events per variable construct our multivariable included maximum eight covariates. assessed performance terms...
To date, most of the evidence suggests that smoking is negatively associated with testing positive for SARS-CoV-2. However, has several methodological limitations. Using an outpatient sample population, we analyzed association SARS-CoV-2 and considering comorbidities, socioeconomic demographic factors. Baseline data were obtained from a cohort during first wave pandemic in Geneva, Switzerland (March-April 2020). RT-PCR tests carried out on individuals suspected having according to strategy...
Introduction Lopinavir/ritonavir (LPV/r) has been proposed as repurposed drugs for pre-exposure and postexposure prophylaxis well therapy of COVID-19. Coronavirus (COPEP) trial aims at assessing their efficacy ring-prophylaxis among adults exposed to SARS-CoV-2. Methods analysis COPEP is a two-arm open-label cluster-randomised conducted in three cantons Switzerland. Asymptomatic contacts (≥16 years) individuals diagnosed with COVID-19 will be randomised (2:1) either LPV/r (400 mg/100 mg two...