A5031889829- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- Cardiac Structural Anomalies and Repair
- Respiratory Support and Mechanisms
- Heart Failure Treatment and Management
- Anesthesia and Sedative Agents
- Thermal Regulation in Medicine
- Sepsis Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and healthcare impacts
- Acute Myocardial Infarction Research
- Anesthesia and Neurotoxicity Research
- Cardiac pacing and defibrillation studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Substance Abuse Treatment and Outcomes
- Cardiac Arrhythmias and Treatments
- COVID-19 and Mental Health
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Issues in Pregnancy
- Pneumonia and Respiratory Infections
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
University Medical Center Freiburg
2011-2024
University of Freiburg
2015-2024
German Society of Medical Intensive Care and Emergency Medicine
2024
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2014-2021
Museum of Heilongjiang Province
2021
Murphy Oil Corporation (United States)
1977-1980
The University of Texas Health Science Center at San Antonio
1977
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) support under cardiopulmonary resuscitation (eCPR) is the last option and may be offered to selected patients. Several factors predict outcome in these patients, including initial heart rhythm, comorbidities, bystander (CPR). We evaluated outcomes of all VA-ECMO patients treated within 5 years at our center respect low-flow duration during CPR.We report retrospective registry data on with eCPR a university hospital between October...
We sought to clarify the benefit of cytokine adsorption in patients with COVID-19 supported venovenous extracorporeal membrane oxygenation (ECMO).We did a single-centre, open-label, randomised, controlled trial investigate adult severe pneumonia requiring ECMO. Patients selected for ECMO at Freiburg University Medical Center (Freiburg, Germany) were randomly assigned (1:1) receive using CytoSorb device or not. Randomisation was computer-generated, allocation concealed by opaque, sequentially...
Prone positioning (PP) reduces mortality of patients with acute respiratory distress syndrome (ARDS). The potential benefit prone maneuvers during venovenous extracorporeal membrane oxygenation (ECMO) is unknown. aim this study was to evaluate the association between use support and ICU in a pooled population from previous European cohort studies.We performed individual patient data analysis studies which compared treated ECMO (Prone group) "conventional" management (Supine severe ARDS.889...
In December 2019, several cases of pneumonia unknown origin have been reported in China, and later, SARS-CoV2 was identified as the causative pathogen for coronavirus disease 2019 (COVID-19) [1. some COVID-19, clinical courses are more severe may be aggravated by secondary infections development an acute respiratory distress syndrome (ARDS) with a high morbidity mortality However, risk factors including patients' medication poorly described. Proton pump inhibitors (PPI) play important role...
Reported mortality of hospitalised Coronavirus Disease-2019 (COVID-19) patients varies substantially, particularly in critically ill patients. So far COVID-19 in-hospital and modes death under state the art care have not been systematically studied.This retrospective observational monocenter cohort study was performed after implementation a non-restricted, dynamic tertiary model at University Medical Center Freiburg, an experienced acute respiratory distress syndrome (ARDS) extracorporeal...
Prone positioning (PP) has shown to improve survival in patients with severe acute respiratory distress syndrome (ARDS). To this point, it is unclear if PP also beneficial for ARDS treated veno-venous extracorporeal membrane oxygenation (VV ECMO) support. We report retrospective data of a single-centre registry requiring VV ECMO support between October 2010 and May 2018. Patients were allocated the group was performed during treatment or supine group. weaning success hospital analysed before...
Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is used to sustain blood and decarboxylation in severe acute respiratory distress syndrome (ARDS). It under debate if V-V ECMO as appropriate for coronavirus disease 2019 (Covid-19) ARDS it influenza. In this retrospective study, we analyzed all patients with confirmed SARS-CoV-2 or influenza A/B infection, ECMO, treated at our medical intensive care unit (ICU) between October 2010 June 2020. Baseline procedural characteristics well...
Hypercoagulability in Coronavirus Disease 2019 (COVID-19) causes deep vein thrombosis and pulmonary embolism necessitating systemic anticoagulation. Case reports of intracerebral hemorrhages ventilated COVID-19 patients warrant precaution. It is unclear, however, if with acute respiratory distress syndrome (ARDS) or without veno-venous extracorporeal membrane oxygenation therapy (VV-ECMO) have more (ICH) compared to other ARDS patients.
Aims Bleeding is a frequent complication in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO). An indication for dual antiplatelet therapy due to coronary stent implantation present considerable number of these patients. The objective this retrospective study was evaluate if (DAPT) significantly increases the high intrinsic bleeding risk VA-ECMO. Methods and Results A total 93 were treated with VA-ECMO between October 2010 2013. Average time 58.9 ± 1.7 hours. Dual given...
The pressures exerted by the coronavirus disease 2019 (COVID-19) pandemic pose an unprecedented demand on healthcare services. Hospitals become rapidly overwhelmed when patients requiring life-saving support outpace available capacities.We describe methods used a university hospital to forecast case loads and time peak incidence.We developed set of models incidence among catchment population COVID-19 patient hospital-care pathway. first utilized data from antecedent allopatric epidemics...
Removal of large calibre arterial sheaths, as employed in venoarterial extracorporeal membrane oxygenation, is still associated with a high risk for vascular access site complications. In this study, we investigated the bore Manta closure device an option oxygenation decannulation.Sixteen patients weaned from between January-June 2019 were prospectively included registry (eight during cardiopulmonary resuscitation, seven severe cardiogenic shock and one patient fulminant pulmonary embolism)....
Veno-venous extracorporeal membrane oxygenation (V-V ECMO) is a last resort treatment option for patients with acute respiratory failure (acute distress syndrome [ARDS]). Cytokine adsorption has been incorporated in the management of some these on an individual basis to control imbalance danger-associated molecular patterns and proinflammatory cytokines. However, little known about combination V-V ECMO cytokine as earlier reports contained mixed patient cohorts terms disease mode ECMO,...
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) can be a rescue therapy for patients in cardiogenic shock or refractory cardiac arrest. After cannulation, vasoplegia and depression are frequent. In literature, there conflicting data on inotropic these patients.Analysis of retrospective registry all treated with VA-ECMO university hospital center between October 2010 December 2018 cardiopulmonary resuscitation (eCPR) focus individual early therapy.A total 231 (age 58.6 ± 14.3,...
Abstract Background Critically ill coronavirus disease 2019 (COVID-19) patients have a high risk of acute kidney injury (AKI) that requires renal replacement therapy (RRT). A state hypercoagulability reduces circuit life spans. To maintain patency and therapeutic efficiency, an optimized anticoagulation strategy is needed. This study investigates whether alternative strategies for RRT during COVID-19 are superior to administration unfractionated heparin (UFH). Methods Retrospective cohort on...
Based on an investigation of the literature from 1951 to 1975, it can be generalized that alcoholism programs featuring multiple treatment components and dealing with a patient class good prognosis might expected achieve 50% success rate at l‐yr follow‐up, in contrast limited resources poor‐prognosis patients, which expect only 15%.
Zusammenfassung Hintergrund Das neue, pandemische Coronavirus SARS-CoV-2 und die damit einhergehende Erkrankung COVID-19 (Coronavirus Disease 2019) stellt medizinischen Versorgungssysteme vor große Herausforderungen. Die vorliegende Arbeit fasst Strategie, Organisation Maßnahmen der COVID-Taskforce des Universitätsklinikums Freiburg zusammen berichtet über Erfahrungen Behandlungsergebnisse von Versorgung ersten 115 COVID-19-Patienten. Methoden Retrospektive, narrative Prozessbeschreibung...
Abstract Objectives This study aimed to identify the incidence and potential risk factors for delirium after myocardial infarction (MI). Background Delirium is a common complication on intensive care units. Data especially predictors of in patients acute MI are rare. Methods In this retrospective study, all hospitalized treated with coronary angiography an university hospital 2018 were included analyzed. Onset within first 5 days was attributed defined by Nursing screening scale (NuDesc) ≥2....
Both antiviral treatment with remdesivir and hemoadsorption using a CytoSorb
Hemodynamic response to successful extracorporeal cardiopulmonary resuscitation (eCPR) is not uniform. Pulse pressure (PP) as a correlate for myocardial damage or recovery from it, might be valuable tool estimate the outcome of these patients.We report retrospective data single-centre registry eCPR patients, treated at Interdisciplinary Medical Intensive Care Unit Centre, University Freiburg, Germany, between 01/2017 and 01/2020. The association PP first 10 days after hospital survival was...