A5085437209- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Emergency and Acute Care Studies
- COVID-19 epidemiological studies
- Dental materials and restorations
- Healthcare cost, quality, practices
- Antibiotic Use and Resistance
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- Advanced Causal Inference Techniques
- Dental Implant Techniques and Outcomes
- Antimicrobial Resistance in Staphylococcus
- COVID-19 and healthcare impacts
- Antibiotic Resistance in Bacteria
- Healthcare Operations and Scheduling Optimization
- Healthcare Policy and Management
- SARS-CoV-2 and COVID-19 Research
- Bacterial Identification and Susceptibility Testing
- Hemodynamic Monitoring and Therapy
- Statistical Methods and Bayesian Inference
- Long-Term Effects of COVID-19
- COVID-19 diagnosis using AI
- Oral microbiology and periodontitis research
- Infection Control in Healthcare
University of Freiburg
2016-2025
Zimmer Biomet (Germany)
2013-2025
University Medical Center Freiburg
2013-2024
Institut für Medizinische Informatik, Biometrie und Epidemiologie
2021
Museum of Heilongjiang Province
2021
Institut für Medizinische Biometrie, Informatik und Epidemiologie
2020
Biology of Infection
2019
Engineering Associates (United States)
2019
Brighton and Sussex Medical School
2018
Sesame Workshop
2015
ABSTRACT Antimicrobial resistance is threatening the successful management of nosocomial infections worldwide. Despite therapeutic limitations imposed by methicillin-resistant Staphylococcus aureus (MRSA), its clinical impact still debated. The objective this study was to estimate excess mortality and length hospital stay (LOS) associated with MRSA bloodstream (BSI) in European hospitals. Between July 2007 June 2008, a multicenter, prospective, parallel matched-cohort carried out 13 tertiary...
The quality and persistence of children's humoral immune response following SARS-CoV-2 infection remains largely unknown but will be crucial to guide pediatric vaccination programs. Here, we examine 548 children 717 adults within 328 households with at least one member a previous laboratory-confirmed infection. We assess serological 3-4 months 11-12 after using bead-based multiplex immunoassay for 23 human coronavirus antigens including its Variants Concern (VOC) endemic coronaviruses...
This study determined excess mortality and length of hospital stay (LOS) attributable to bloodstream infection (BSI) caused by third-generation-cephalosporin-resistant Escherichia coli in Europe. A prospective parallel matched cohort design was used. Cohort I consisted patients with E. BSI (REC) II third-generation-cephalosporin-susceptible (SEC). Patients both cohorts were for LOS before free the respective BSI. Thirteen European tertiary care centres participated between July 2007 June...
flawed results and conclusions.This article uses a real dataset simple simulation to show how standard analysis fails such data should be analysed
Abstract Introduction Pneumonia is a very common nosocomial infection in intensive care units (ICUs). Many studies have investigated risk factors for the development of and its consequences. However, evaluation most theses disregards fact that there are additional competing events, such as discharge or death. Methods A prospective cohort study was conducted over 18 months five at one university hospital. All patients were admitted least 2 days included, surveillance pneumonia conducted....
Abstract Biofilm formation was evaluated on the following titanium and zirconia implants in vivo : machined (Ti‐m), modified (TiUnite ® ), (ZiUnite alumina‐toughened (ATZ‐m), sandblasted (ATZ‐s), (TZP‐A‐m). Bovine enamel slabs were used as controls. Surface morphologies examined by atomic force (AFM) scanning electron microscopy (SEM). The surface wettability also determined. Twelve healthy volunteers wore a splint system with tested materials. After 3 5 days materials fluorescence situ...
The clinical progress of patients hospitalized due to COVID-19 is often associated with severe pneumonia which may require intensive care, invasive ventilation, or extracorporeal membrane oxygenation (ECMO). length care and the duration these supportive therapies are clinically relevant outcomes. From statistical perspective, quantities challenging estimate episodes being time-dependent potentially multiple, as well determined by competing, terminal events discharge alive death.
Abstract Objective: This study aimed at evaluating the integration of zirconia implants in a rat femur model. Material and methods: Zirconia with two distinct surface topographies were compared titanium similar topographies. Titanium placed into femurs 42 male Sprague–Dawley rats. Four groups utilized: machined implants, rough surface, an electrochemically roughened surface. After healing period 28 days, load‐bearing capacity between bone implant was evaluated by push‐in test. Additionally,...
Abstract Aim To determine the influence of solvents on gutta‐percha and sealer remaining root canal walls in dentinal tubules. Methodology The canals 70 teeth were prepared chemomechanically to apical size 40. In group 1 ( n = 10; control group), remained unfilled. groups 2–4 20 each), filled using lateral compaction with sealer. Removal fillings was undertaken after 2 weeks Gates Glidden burs hand files without solvent (group 2), eucalyptol (60 μL; 3) chloroform 4) 50. After further...
Research on hospital-acquired infections (HAIs) requires the highest methodological standards to minimize risk of bias and avoid misleading interpretation. There are two major issues related specifically studies in this area, namely timing infection occurrence so-called competing risks, which deserve special attention. Just as a patient who acquires serious during hospital admission needs appropriate antibiotic treatment, data being collected need statistical analysis. We illustrate urgent...
Zirconia is a potential material for the fabrication of oral implants. The aim this study was to evaluate effects cyclic loading and preparation on fracture strength zirconia implant system.Forty-eight one-piece implants were divided into two groups 24 implants: group A (without modification) B (1 mm chamfer preparation). Groups three subgroups eight each = no artificial load, 2 load [98 N; 1.2 million cycles], 3 5 cycles]). After completion loading, determined in universal testing machine....
OBJECTIVES: To evaluate the fate of a dissected aortic arch after limited surgical repair type A dissection. METHODS: Of 271 patients operated for acute dissection between 2001 and 2015, 86 (age 57 ± 13 years, 74% men) with predischarge computed tomographic (CT) scans had residual in arch. Aortic diameters, lengths, ellipticity communications lumina were assessed using follow-up CT scans. The median scan was 31 months (first quartile 15, third 52). RESULTS: largest increase total diameter at...