A5062580342- Dental Implant Techniques and Outcomes
- Dental materials and restorations
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Dental Radiography and Imaging
- Cardiac pacing and defibrillation studies
- Endodontics and Root Canal Treatments
- Periodontal Regeneration and Treatments
- Cardiac electrophysiology and arrhythmias
- Orthodontics and Dentofacial Orthopedics
- Advanced Nanomaterials in Catalysis
- Cardiac Arrhythmias and Treatments
- Ion channel regulation and function
- Neurological disorders and treatments
- Respiratory and Cough-Related Research
- Advanced Photocatalysis Techniques
- Pharmacological Effects of Natural Compounds
- Tissue Engineering and Regenerative Medicine
- Cardiovascular Effects of Exercise
- dental development and anomalies
- Various Chemistry Research Topics
- Polymer Surface Interaction Studies
- Dental Trauma and Treatments
- Receptor Mechanisms and Signaling
- Polymer Synthesis and Characterization
University of Freiburg
2001-2025
University Medical Center Freiburg
2005-2023
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2023
University of California, Los Angeles
2005-2011
University of Michigan–Ann Arbor
2002
summary The aim of this study was to compare titanium‐reinforced ZrO 2 and pure Al O 3 abutments regarding their outcome after chewing simulation static loading. Forty‐eight standard diameter implants with an external hexagon were divided into three groups 16 each restored different types (group A: titanium inserts; group B: abutments; C: abutments). All fixated on the gold‐alloy screws at 32 Ncm torque, metal crowns adhesively cemented onto abutments. specimens exposed 1·2 million cycles in...
Mechanisms underlying the beneficial anchorage of roughened titanium implants have not been identified. We hypothesized that implant surface roughness alters intrinsic biomechanical properties bone integrated to titanium. Nano-indentation performed on two- and four-week post-implantation specimens rats revealed acid-etched was approximately 3 times harder than machined titanium, both at osseointegration interface inner area peri-implant bone. The hardness surface-associated equivalent...
Abstract Objective: This study aimed at evaluating the integration of zirconia implants in a rat femur model. Material and methods: Zirconia with two distinct surface topographies were compared titanium similar topographies. Titanium placed into femurs 42 male Sprague–Dawley rats. Four groups utilized: machined implants, rough surface, an electrochemically roughened surface. After healing period 28 days, load‐bearing capacity between bone implant was evaluated by push‐in test. Additionally,...
Because of its inherent strength, biocompatibility, and tooth-like color, zirconia ceramics have the potential to become an alternative titanium as dental implant material. This study aimed at investigating osteoblastic response yttrium-stabilized tetragonal polycrystal (Y-TZP) with different surface topographies.CAL72 osteoblast-like cells were cultured on machined (TZP-m), airborne particle abraded (TZP-s), acid-etched Y-TZP (TZP-sa) surfaces. Polystyrene large grit (SLA) served a...
To investigate the clinical and radiographic outcome of a one-piece zirconia oral implant for single tooth replacement after 1 year.A total 65 patients received one-stage surgery with immediate temporization. Standardized radiographs were taken at insertion year to monitor peri-implant bone loss. A univariate analysis influence different baseline parameters on marginal loss from 12 months was performed. Soft tissue evaluated prosthesis 1-year follow-up.After year, three implants lost, giving...
Abstract This study revealed that osteoblasts generate harder, stiffer, and more delamination-resistant mineralized tissue on titanium than the culture polystyrene, associated with modulated gene expression, uniform mineralization, well-crystallized interfacial calcium-phosphate layer, intensive collagen deposition. Knowledge of this titanium-induced alteration osteogenic potential leading to enhanced intrinsic biomechanical properties provides novel opportunities implications for...
To evaluate the clinical and radiological outcome of one-piece zirconia oral implants for three-unit fixed dental prosthesis (FDP) replacement after 1 year.Twenty eight patients were recruited investigation signed an informed consent. All treated with a one-stage implant surgery immediate temporary restoration on two implants. The fabricated yttria-stabilized tetragonal (y-TZP). endosseous part was tapered porous surface. A total 56 inserted in 28 patients. 12 placed upper jaws (six anterior...
ABSTRACT Objectives The purpose of the present prospective case series was to investigate clinical and radiological outcome one‐piece zirconia implants fabricated from 3Y‐TZP with a moderately roughened endosseous surface (Sa = 1.24 μm) support three‐unit fixed dental prostheses (FDP) after five years in function. Materials Methods Twenty‐seven patients received total 54 one‐stage surgery immediate provisionalization. Peri‐implant bone loss assessed using standardized radiographs....
We report here a new versatile method to deposit discrete hydroxyapatite (HA) nanoparticles on titanium (Ti) implant with predisposing substrate microtopography, which exhibited an unexpectedly robust biological effect. Commercially pure Ti substrates were treated 3-aminopropyltriethoxysilane, HA (20 nm) deposited and chemically bonded TiO2. The deposition rate was linearly related the treatment time up 50% of surface. As result, generated novel 20–40 nm nanotopography microtopography that...
The intention of this 5-year prospective cohort investigation was to clinically and radiographically investigate the outcomes a one-piece zirconia implant system for single tooth replacement. Sixty-five patients received total 66 single-tooth implants. All implants immediately temporary restorations were finally restored with all-ceramic crowns. Follow-ups performed at prosthetic delivery, after 1, 3, 5 years. Peri-implant dental soft-tissue parameters evaluated patient-reported recorded. To...
Biomechanical properties of the bone-titanium interface have rarely been studied, due to technical limitations involved; whether biological bonding mechanisms exist has not determined. We hypothesized that a selected set proteoglycan/glycosaminoglycan complexes plays role in establishing adhesion between bone and titanium, utilized rat bone-marrow-derived osteoblastic culture model gain an insight into hypothesis. Gene expression proteoglycan core proteins was up-regulated osteoblasts...
Abstract The development of long‐lasting zirconia‐based ceramics for implants, which are not prone to hydrothermal aging, is satisfactorily solved. Therefore, this study conceived as an overall evaluation screening novel ceria‐stabilized zirconia–alumina–aluminate composite (ZA 8 Sr ‐Ce11) with different surface topographies use in clinical applications. Ceria‐stabilized zirconia chosen the matrix material, due its lower susceptibility aging than yttria‐stabilized (3Y‐TZP). This assessment...
summary The aim of this in vitro study was to evaluate the fracture load and marginal accuracy crowns made from a shrinkage‐free ZrSiO 4 ceramic cemented with glass–ionomer or composite cement after chewing simulation. Thirty‐two human mandibular molars were randomly divided into two groups. All teeth prepared for restored (Everest HPC®, KaVo). group A ( N = 16) luted using KetacCem® B adhesively Panavia®21EX. Measurements before cementation replicas an image analysis system. specimens...
Abstract Aim This 3‐year report of a prospective long‐term cohort investigation aimed to evaluate the clinical and radiographic outcomes one‐piece zirconia oral implant for single‐tooth replacement. Materials Methods Sixty‐five patients received 1‐stage surgery with immediate temporization. Standardized radiographs were taken at insertion, after 1 year, 3 years monitor peri‐implant bone levels. A univariate analysis association different baseline parameters on marginal loss from insertion 36...
Abstract Although the localization of proteoglycan/glycosaminoglycan (GAG) complex at bone–titanium implant interface has been implied, role proteoglycans on establishment integration is unknown. The hypothesis to be tested was that play an important in establishing interfacial adhesion. objective this study investigate effect proteoglycan knockdown by GAG enzymatic degradation strength between mineralized tissue and titanium having different surface topographies. Rat bone marrow‐derived...
Abstract Objectives: Alumina toughening enhances the mechanical properties of zirconia ceramics but biocompatibility this material has rarely been addressed. In study, we examined osteoblast response to alumina‐toughened (ATZ) with different surface topographies. Material and methods: Human osteoblasts isolated from maxillary biopsies four patients were cultured seeded onto disks following substrates: ATZ a machined surface, airborne‐particle abraded ATZ, acid etched ATZ. Airborne‐particle...