Uga Dumpis
A5067384869- Antibiotic Use and Resistance
- Influenza Virus Research Studies
- Antibiotic Resistance in Bacteria
- Nosocomial Infections in ICU
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Antimicrobial Resistance in Staphylococcus
- Urinary Tract Infections Management
- Patient Satisfaction in Healthcare
- Computational Drug Discovery Methods
- COVID-19 epidemiological studies
- interferon and immune responses
- Liver Disease Diagnosis and Treatment
- SARS-CoV-2 detection and testing
- Infection Control in Healthcare
- Enterobacteriaceae and Cronobacter Research
- Dental Research and COVID-19
- Pneumonia and Respiratory Infections
- Bacterial Identification and Susceptibility Testing
- Infective Endocarditis Diagnosis and Management
- Pharmaceutical and Antibiotic Environmental Impacts
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Central Venous Catheters and Hemodialysis
- Streptococcal Infections and Treatments
Pauls Stradiņš Clinical University Hospital
2013-2024
University of Latvia
2003-2024
Latvian Biomedical Research and Study Centre
2019-2020
Bridge University
2020
Radboud University Nijmegen
2018
Radboud University Medical Center
2018
Centre Hospitalier Régional et Universitaire de Nancy
2016
Hospital for Tropical Diseases
2016
Université Paris-Est Créteil
2015
Inserm
2015
Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed estimate the burden of infections caused by public concern in countries EU European Economic Area (EEA) 2015, measured number cases, deaths, disability-adjusted life-years (DALYs).We estimated incidence with 16 antibiotic resistance-bacterium combinations from Antimicrobial Resistance Surveillance Network...
Intensive care units (ICUs) are high-risk areas for transmission of antimicrobial-resistant bacteria, but no controlled study has tested the effect rapid screening and isolation carriers on in settings with best-standard precautions. We assessed interventions to reduce colonisation bacteria European ICUs.We did this three phases at 13 ICUs. After a 6 month baseline period (phase 1), we an interrupted time series universal chlorhexidine body-washing combined hand hygiene improvement months...
Infections with carbapenem-resistant Enterobacteriaceae (CRE) are increasingly being reported from patients in healthcare settings. They associated high patient morbidity, attributable mortality and hospital costs. Patients who "at-risk" may be carriers of these multidrug-resistant (MDR-E). The purpose this guidance is to raise awareness identify the when admitted a setting outline effective infection prevention control measures halt entry spread CRE. was created by group experts were...
This study determined excess mortality and length of hospital stay (LOS) attributable to bloodstream infection (BSI) caused by third-generation-cephalosporin-resistant Escherichia coli in Europe. A prospective parallel matched cohort design was used. Cohort I consisted patients with E. BSI (REC) II third-generation-cephalosporin-susceptible (SEC). Patients both cohorts were for LOS before free the respective BSI. Thirteen European tertiary care centres participated between July 2007 June...
Since electronic prescribing is limited to few hospitals, point prevalence surveys, such as the standardized European Surveillance of Antimicrobial Consumption survey (ESAC PPS), are an alternative tool for monitoring and helping identify performance indicators trends. The main objective this study was assess targets quality improvement. Each hospital had carry out within 2 weeks. department be surveyed in 1day. Data collected, all inpatients, included age gender. For patients on systemic...
To perform the first multinational Enterobacter cloacae clonality study, using MLST scheme newly developed in Japan.The analysis included 195 rectal carriage E. isolates resistant to expanded-spectrum cephalosporins (ESCs), collected from patients 12 hospital units across Europe and Israel. All of were typed by PFGE 173 subjected MLST. ESC resistance was analysed phenotypically; genes encoding ESBLs carbapenemases identified PCR sequencing.MLST distinguished 88 STs, which correlated with...
With the increasing pace of global warming, it is important to understand role meteorological factors in influenza virus (IV) epidemics. In this study, we investigated impact temperature, UV index, humidity, wind speed, atmospheric pressure, and precipitation on IV activity Norway, Sweden, Finland, Estonia, Latvia Lithuania during 2010–2018. Both correlation machine learning analyses revealed that low temperature indexes were most predictive for epidemics Northern Europe. Our vitro...
• Resistance to nitrofurantoin, fosfomycin and mecillinam was <10% for E. coli isolates. Viable first-line treatments were not always available. Trimethoprim Trim/sulfa recommended as despite high resistance. Over-the-counter sales of furazidin could explain higher resistance nitrofurantoin. Russian patients had a risk outpatient UTI caused by resistant . In the Northern Dimension Antibiotic Study (NoDARS), Finland, Germany, Latvia, Poland, Russia Sweden collected urine samples from women...
Viruses are one of the major causes acute and chronic infectious diseases thus a contributor to global burden disease. Several studies have shown how viruses evolved hijack basic cellular pathways evade innate immune response by modulating key host factors signalling pathways. A collective view these multiple could advance our understanding virus-host interactions provide new therapeutic perspectives for treatment viral diseases. Here, we performed an integrative meta-analysis elucidate 17...
To assess the total systemic antiviral use in Europe and to identify substances most commonly used. Within European Surveillance of Antimicrobial Consumption (ESAC; www.esac.ua.ac.be), using anatomical therapeutic chemical (ATC) classification defined daily dose (DDD) measurement unit, data on (out- inpatient) (ATC J05), aggregated at level active substance, were collected for 2008, was expressed DDD (WHO ATC/DDD, version 2010) per 1000 inhabitants day (DID). Antiviral grouped according...
ObjectivesThe aim of this study was to investigate antimicrobial prescribing in nursing homes countries across Europe.
Persistent hepatitis B virus infection is a major risk factor for hepatocellular carcinoma, the most frequent cancer in some developing countries. Up to 95% of those infected at birth and 15% after neonatal period fail clear virus, together resulting approximately 350 million persistent carriers worldwide. Via whole genome scan Gambian families, we have identified susceptibility locus as cluster class II cytokine receptor genes on chromosome 21q22. Coding changes two these genes, type I IFN...
In an era of antibiotic resistance, medical students must be prepared to prescribe antibiotics responsibly. To assess self-reported preparedness among final-year at European universities, using a comprehensive set topics related prudent use. We conducted cross-sectional, multicentre, web-based survey. All medical-degree in their final year studies universities were eligible participate. A score was calculated for each student and mean scores compared school country levels. Comparisons made...
ObjectiveTo develop a consensus-based set of generic competencies in antimicrobial prescribing and stewardship for European prescribers through structured consensus procedure.MethodsThe RAND-modified Delphi procedure comprised two online questionnaire rounds, face-to-face meeting between final review. Our departure point was agreed previously by among UK multi-disciplinary panel, which had been subsequently revised consultation with ESCMID Study Group representatives. The 46 draft competency...
Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen One Health antimicrobial resistance (AMR) surveillance approach.