Amos Adler
A5046117492- Antibiotic Resistance in Bacteria
- Enterobacteriaceae and Cronobacter Research
- Bacterial Identification and Susceptibility Testing
- Antibiotics Pharmacokinetics and Efficacy
- Streptococcal Infections and Treatments
- Antibiotic Use and Resistance
- Pneumonia and Respiratory Infections
- Clostridium difficile and Clostridium perfringens research
- Antimicrobial Resistance in Staphylococcus
- Urinary Tract Infections Management
- Nosocomial Infections in ICU
- Mycobacterium research and diagnosis
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 and COVID-19 Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Microscopic Colitis
- Tuberculosis Research and Epidemiology
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Infective Endocarditis Diagnosis and Management
- Vibrio bacteria research studies
- Infectious Diseases and Mycology
- Escherichia coli research studies
- Gut microbiota and health
- Bacteriophages and microbial interactions
Tel Aviv Sourasky Medical Center
2015-2024
Tel Aviv University
2015-2024
Rambam Health Care Campus
2023
Czech Academy of Sciences, Institute of Microbiology
2022
Israel Ministry of Health
2011-2019
Engineering Associates (United States)
2017-2018
Reuth Medical & Rehabilitation Center
2014
Ben-Gurion University of the Negev
2014
Office of Infectious Diseases
2012
University of Chicago Medical Center
2011
Abstract Candida auris and C. haemulonii are closely related, multidrug-resistant emerging fungal pathogens that not readily distinguishable with phenotypic assays. We studied clinical isolates from 2 hospitals in central Israel. was isolated 5 patients nosocomial bloodstream infection, found as a colonizer of leg wounds at peripheral vascular disease clinic. Liberal use topical miconazole close contact among were implicated transmission. exhibited higher thermotolerance, virulence mouse...
Abstract In some immunocompromised patients with chronic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, considerable adaptive evolution occurs. Some substitutions found in infections are lineage-defining mutations variants of concern (VOCs), which has led to the hypothesis that VOCs emerged from infections. this study, we searched for drivers VOC-like emergence by consolidating sequencing results a set 27 Most reflected VOC mutations; however, subset associated...
To perform the first multinational Enterobacter cloacae clonality study, using MLST scheme newly developed in Japan.The analysis included 195 rectal carriage E. isolates resistant to expanded-spectrum cephalosporins (ESCs), collected from patients 12 hospital units across Europe and Israel. All of were typed by PFGE 173 subjected MLST. ESC resistance was analysed phenotypically; genes encoding ESBLs carbapenemases identified PCR sequencing.MLST distinguished 88 STs, which correlated with...
ABSTRACT The increased worldwide spread of carbapenem-resistant Enterobacteriaceae (CRE) emphasizes the need for a sensitive screening procedure to identify these microorganisms. Gastrointestinal carriers may serve as reservoir cross-transmission in health care setting, and thus active surveillance is key part preventing such strains. Three agar-based methods direct CRE detection from rectal swabs were compared: CHROMagar-KPC (Chrom); MacConkey agar with imipenem at 1 μg/ml (MacI); plates...
Significance In many clinically important bacteria, antibiotic resistance genes are primarily carried on plasmids. These can spread horizontally between different strains and species. However, current surveillance systems track chromosomal lineages of bacteria only, leading to an incomplete understanding how spreads, from within individual hospital across country borders. We present integrated, high-resolution analysis both chromosome plasmid sequences using Klebsiella pneumoniae isolates...
Abstract Background We evaluated the association between mortality and colistin resistance in Acinetobacter baumannii infections interaction with antibiotic therapy. Methods This is a secondary analysis of randomized controlled trial patients carbapenem-resistant gram-negative bacterial treated or colistin-meropenem combination. infection caused by A. (CRAB) identified as susceptible (CoS) at time treatment compared which isolate was confirmed CoS those whose isolates were retrospectively...
Abstract A high neutrophil to lymphocyte ratio (NLR) is considered an unfavorable prognostic factor in various diseases, including COVID-19. The value of NLR other respiratory viral infections, such as Influenza, has not hitherto been extensively studied. We aimed compare the COVID-19, Influenza and Respiratory Syncytial Virus infection (RSV). retrospective cohort RSV patients admitted Tel Aviv Medical Center from January 2010 October 2020 was analyzed. Laboratory, demographic, clinical...
In the last decade, global emergence of carbapenem resistance in Enterobacteriaceae has posed great concern to public health. Data concerning role environmental contamination dissemination carbapenem-resistant (CRE) are currently lacking. Here, we aimed examine extent CRE various sites immediate surroundings carriers and assess effects sampling time cleaning regimens on recovery rate. We evaluated performance two methods, CHROMAgar KPC contact plate eSwab, for detection CRE. eSwab was...
Little is known about vaccine efficacy and sustainability among people with HIV (PWH). We estimated humoral cellular immune responses postvaccination BNT162b2 mRNA coronavirus disease 2019 (COVID-19) PWH in Tel-Aviv Medical Center.The response was evaluated by measuring immunoglobulin G (IgG) titers of antispike receptor-binding domain antibodies (anti-RBD IgG). Cellular assessed stimulating donor peripheral blood mononuclear cells pooled complete S-peptide mix.One hundred thirty-six who...
The carbapenemase OXA-48 has been reported from different Mediterranean countries. It is mostly encoded on a single plasmid in various Enterobacteriaceae species. We characterized the epidemiological and molecular features of OXA-48-producing (OPE) Israel. Epidemiological investigation was conducted by National Center for Infection Control. Genotyping performed using multilocus sequence typing. blaOXA-48-carrying plasmids were investigated S1 endonuclease restriction fragment length...
The prospective project MOSAR was conducted in five rehabilitation units: the Berck Maritime Hôpital (Berck, France), Fondazione Santa Lucia (Rome, Italy), Guttmann Institute (GI; Barcelona, Spain), and Loewenstein Hospital Tel-Aviv Souraski Medical Center (TA) (Tel-Aviv, Israel). Patients were screened for carriage of Enterobacteriaceae resistant to expanded-spectrum cephalosporins (ESCs) from admission until discharge. aim this study characterize clonal structure, extended-spectrum...