A5087319030- Antibiotic Resistance in Bacteria
- Pharmaceutical and Antibiotic Environmental Impacts
- Vibrio bacteria research studies
- Bacterial biofilms and quorum sensing
- Antibiotics Pharmacokinetics and Efficacy
- Enterobacteriaceae and Cronobacter Research
- Infections and bacterial resistance
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Escherichia coli research studies
- Mycobacterium research and diagnosis
- Bacterial Genetics and Biotechnology
- Tuberculosis Research and Epidemiology
- Salmonella and Campylobacter epidemiology
- Pneumonia and Respiratory Infections
- Plant Pathogenic Bacteria Studies
- Bacteriophages and microbial interactions
- CRISPR and Genetic Engineering
- Antimicrobial Resistance in Staphylococcus
- Urinary Tract Infections Management
- Genomics and Phylogenetic Studies
- Viral-associated cancers and disorders
- Cytomegalovirus and herpesvirus research
- Pneumocystis jirovecii pneumonia detection and treatment
- Cancer therapeutics and mechanisms
University of Fribourg
2016-2025
Inserm
2015-2024
University of Lausanne
2017-2024
Institut Pasteur
2023-2024
HES-SO Genève
2023
Institut Pasteur de Lille
2022
Université de Lille
2022
University of Bern
2021
Université Paris Cité
2002-2020
CNR de la Résistance aux Antibiotiques
2006-2019
Klebsiella pneumoniae strain 11978 was isolated in Turkey 2001 and found to be resistant all beta-lactams, including carbapenems. Cloning expression Escherichia coli identified five beta-lactamases, two novel oxacillinases. The beta-lactamase OXA-48 hydrolyzed imipenem at a high level remotely related (less than 46% amino acid identity) the other It penicillins but not expanded-spectrum cephalosporins. bla(OXA-48) gene plasmid encoded associated with an integron, contrast most of...
Acinetobacter baumannii is a species of nonfermentative gram-negative bacteria commonly found in water and soil. This organism was susceptible to most antibiotics the 1970s. It has now become major cause hospital-acquired infections worldwide due its remarkable propensity rapidly acquire resistance determinants wide range antibacterial agents. Here we use comparative genomic approach identify complete repertoire genes exhibited by multidrug-resistant A. strain AYE, which epidemic France, as...
Abstract To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on vitro hydrolysis of a carbapenem, imipenem. It was 100% sensitive specific compared with molecular-based techniques. This rapid (<2 hours), inexpensive technique may be implemented any laboratory.
Abstract We analyzed 43 CTX-M-15–producing Escherichia coli isolates and 6 plasmids encoding the blaCTX-M-15 gene from Canada, India, Kuwait, France, Switzerland, Portugal, Spain. Most belonged to phylogroups B2 (50%) D (25%). An EC-B2 strain of clonal complex sequence type (ST) 131 was detected in all countries; other corresponded ST28, ST405, ST354, ST695 specific areas. EC-D strains were clonally unrelated but 3 countries ST405. All CTX-M-15 IncFII group with overrepresentation...
ObjectivesTo develop a rapid and reliable single-tube-based PCR technique for detecting simultaneously the plasmid-mediated quinolone resistance qnrA, qnrB qnrS genes.
ABSTRACT Pseudomonas aeruginosa COL-1 was identified in a blood culture of 39-year-old-woman treated with imipenem Marseilles, France, 1996. This strain resistant to β-lactams, including ureidopenicillins, ticarcillin-clavulanic acid, cefepime, ceftazidime, imipenem, and meropenem, but remained susceptible the monobactam aztreonam. The carbapenem-hydrolyzing β-lactamase gene P. cloned, sequenced, expressed Escherichia coli DH10B. deduced 266-amino-acid protein an Ambler class B β-lactamase,...