- Pregnancy and preeclampsia studies
- Ectopic Pregnancy Diagnosis and Management
- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Maternal and fetal healthcare
- Neurogenesis and neuroplasticity mechanisms
- Maternal and Perinatal Health Interventions
- Immune Response and Inflammation
- Gestational Diabetes Research and Management
- Congenital Heart Disease Studies
- Ovarian function and disorders
- Photoreceptor and optogenetics research
- Gynecological conditions and treatments
- Reproductive Biology and Fertility
- Neonatal Respiratory Health Research
- Craniofacial Disorders and Treatments
- Apelin-related biomedical research
- Reproductive Health and Contraception
- Electrochemical sensors and biosensors
- Medical and Biological Sciences
- Advanced Glycation End Products research
- Homicide, Infanticide, and Child Abuse
- Maternal and Neonatal Healthcare
- Vascular Malformations and Hemangiomas
- Neuroendocrine regulation and behavior
Assaf Harofeh Medical Center
2014-2024
Tel Aviv University
2007-2024
Weizmann Institute of Science
1972-2020
Bar-Ilan University
2014-2019
Alzheimer's Association of Israel
2019
Sheba Medical Center
2015-2016
Lenox Hill Hospital
2008
Wolfson Medical Center
2002-2007
Neurogenesis, the formation of new neurons in adult brain, is important for memory and extinction. One most studied external interventions that affect rate neurogenesis physical exercise. Physical exercise promotes via several factors including brain-derived neurotrophic factor (BDNF) vascular endothelial growth (VEGF). Here, we identified L-lactate, a exercise-induced metabolite, as hippocampal neurogenesis. While prolonged exposure to L-lactate promoted neurogenesis, no beneficial effect...
Recently it has been found that the presence of homozygous arginine polymorphism at codon 72 p53, represents a significant risk factor in development HPV-associated cervical cancer. The incidence carcinoma is persistently very low Israeli Jewish women for unknown reasons. among those North African origin relatively higher. aim present study was to assess frequency distribution p53 cancer patients and population sample healthy order determine whether pattern them genetically based. cases...
Objective To evaluate the distribution of first- and second-trimester maternal serum markers in twin pregnancy with without pre-eclampsia. Methods One-hundred forty-four 109 unaffected singleton pregnancies were recruited from same institution. First- blood samples stored measured retrospectively for placental growth factor (PlGF), pregnancy-associated plasma protein-A (PAPP-A), free β-human chorionic gonadotropin (β-hCG) α-fetoprotein (AFP). All had measurement first-trimester markers, 167...
Abstract Objective To evaluate the incidence of chromosomal aberrations and clinical outcomes following prenatal diagnosis isolated perimembranous ventricular septal defect (pVSD). Methods This retrospective study was composed a cohort pregnant women whose fetuses were diagnosed with pVSD. Complete examinations fetal heart performed, as well postnatal validation echocardiography follow‐up at 1 year age. The collected data included: spontaneous closure pVSD, need for intervention, outcome....
To construct prenatal age-specific reference intervals using ultrasound measurement of total axial length (TAL) in normal fetuses for assessing microphthalmia.Prospective cross-sectional study assessed at a unit between 2011 and 2014. The cohort comprised 309 pregnant women attending routine fetal biometry, viability, or anomaly scan 14 41 weeks gestation. Only singleton viable fetus with anatomy, adequate amniotic fluid, accurate gestational age, no maternal medical complications pregnancy...
With the recent trend toward single embryo transfer (ET), cryopreservation of extraneous embryos is becoming increasingly prevalent. Several replacement protocols for frozen-thawed ET (FET) exist, with no advantage one protocol over others. All consecutive patients undergoing natural cycle Day-3 FET cycles between May 2012 and March 2015 in our IVF unit were evaluated. While following spontaneous ovulation, all received progesterone luteal support. Since June 2014, underwent same...
The association between cardiovascular fitness and cognitive functions in both animals humans is intensely studied. Research rodents shows that a higher has beneficial effects on hippocampus-dependent spatial abilities, the underlying mechanisms were largely teased out. into impact of learning humans, however, more limited, involves mostly behavioral imaging studies. Herein, we point out state art field fitness. differences methodologies utilized to study are emphasized along with neuronal...
Objective: To assess fetal abnormalities leading to very late termination of pregnancy (VLTOP) performed after 32 weeks' gestation.Method: The study population included all pregnant women with singleton that underwent VLTOP in our institute because indications between the years 1998 and 2015.Results: Fifty-seven cases (2.0%) were at ≥32 gestation are subjects current study. Our subdivided into four categories according sequence events led decision for VLTOP: (1) No routine prenatal screening...
Background Retention of conception products is a common complication following delivery and remains diagnostic management challenge due to non-specific symptoms ultrasound findings. Purpose To introduce clinical approach for managing patients with suspected retained delivery. Material Methods The examination included gray-scale Doppler parameters which classified the into three groups: high, moderate, or low probability conception. same classification was used both stratify individual risk...
Suspicion of retained products conception (RPOC) often arises after delivery and still poses a diagnostic management challenge.To prospectively evaluate sonographic classification for the patients with suspected RPOC delivery.Based on grayscale Doppler ultrasound parameters, were classified into high, moderate, or low probability RPOC. For moderate groups, an follow-up at end puerperium was recommended. high group, examination conducted 10-14 days first ultrasound, persistent findings...
To evaluate the new ultrasound-based signs for diagnosis of post-cesarean section uterine niche in nonpregnant women.We investigated prospectively a cohort 160 consecutive women with one previous term cesarean delivery (CD) between December 2019 and 2020. All were separated into two subgroups according to different stages labor at time their CD: subgroup A (n = 109; 68.1%) elective CD performed latent cervical dilatation (≤4 cm) B 51; 31.9%); during active stage (>4 cm).Overall, incidence...
To assess fetal abnormalities leading to termination of pregnancy (TOP) performed in twin pregnancies.The current study consisted all women with dichorionic pregnancies (study group) who underwent TOP due our institute from 1999 2015. The data were compared registry parturient a singleton (control that anomalies at the same period.There 2495 cases because indications during period. Of them, 86 (3.4%) and 2409 (96.6%) control group, respectively. Structural indication for twins (81.4% versus...
Breast engorgement and galactorrhea occasionally occur during tocolysis with ritodrine. We are not aware of breast associated other tocolytics. report the first case intravenous magnesium sulfate in a generally healthy 24-year-old woman admitted for at 30 weeks' gestation. gradually subsided after was discontinued. The rapid disappearance both discontinuation treatment suggests cause-effect relationship, mechanism which remains unclear.
Background and Objectives: In response to the COVID-19 pandemic, Israel prioritized pregnant women for vaccination, recognizing them as a high-risk group. This study aims explore factors influencing acceptance of Influenza, Pertussis (T-dap), vaccines among women, focusing on attitudes, social norms, perceived control, risk perceptions. Additionally, compares patterns between traditional newer vaccine. Methods: A prospective cohort was conducted December 2019 2021 involving 449 predominantly...
Umbilical vein varix (UVV) is defined as a focal enlargement of the umbilical and represents approximately 4% fetal cord malformations. The reported neonatal outcome fetuses with UVV varies widely due to its rarity, hence small sample sizes case series in literature. Earlier studies high mortality, but more recent reports have demonstrated no association between intrauterine death. A study has described possible diagnosed prenatally child developmental delay. present was done evaluate...