- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Pregnancy and preeclampsia studies
- Cleft Lip and Palate Research
- Maternal and fetal healthcare
- Fetal and Pediatric Neurological Disorders
- Maternal and Perinatal Health Interventions
- Congenital Anomalies and Fetal Surgery
- Birth, Development, and Health
- Gestational Trophoblastic Disease Studies
- Congenital Heart Disease Studies
- Craniofacial Disorders and Treatments
- COVID-19 Impact on Reproduction
- Genomic variations and chromosomal abnormalities
- Gynecological conditions and treatments
- Congenital heart defects research
- Congenital Diaphragmatic Hernia Studies
- Pregnancy and Medication Impact
- Reproductive System and Pregnancy
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Neonatal and fetal brain pathology
- Urological Disorders and Treatments
- Pregnancy-related medical research
Ben-Gurion University of the Negev
2023-2025
Assaf Harofeh Medical Center
2014-2024
Assuta Medical Center
2023-2024
Tel Aviv University
2014-2023
Tel Hai Academic College
2023
Rebecca Sieff Hospital
2023
Screen
2023
Rabin Medical Center
2010-2022
Rafael Advanced Defense Systems (Israel)
2021-2022
Tel Aviv Sourasky Medical Center
2015-2019
To evaluate the accuracy of an ultrasound-based scoring system for diagnosing morbidly adherent placenta (MAP).This study included pregnant women referred to our ultrasound unit during 2013-2015 because suspected MAP on a previous examination or they had at least one Cesarean delivery. All were assessed using based following: number and size placental lacunae; obliteration demarcation between uterus placenta; location; color Doppler signals within hypervascularity placenta-bladder and/or...
The purpose of this study was to assess fertility performance and obstetric outcomes after treatment cesarean scar pregnancy.We conducted a retrospective in large tertiary hospital Israel. included 18 women with diagnosis pregnancy between 2000 2009.The incidence among our parturient patients 1 per 3000 for the general population 531 those at least delivery. Sixteen were treated primarily methotrexate. Two by surgery, 2 more surgery failed methotrexate treatment. After treatment, 7 conceived...
Objectives The objective of this study is to evaluate the incidence chromosomal aberration (both microscopic and sub-microscopic) in fetuses with an aberrant right subclavian artery (ARSA) detected by ultrasonographic anomaly scan. Methods included 62 pregnant women whose were diagnosed ARSA who referred for genetic counseling. Of these, 55 patients underwent amniocentesis 7 declined invasive testing. All samples tested standard G-banding microarray, except 2 which only karyotype...
Chromosomal aberrations are a common cause for miscarriage. The purpose of this study was to evaluate factors that influence the frequency chromosomal abnormalities in miscarriages and provide clinicians with guideline management such cases.The included 170 women who experienced pregnancy loss between 2004 2014. Cytogenetic analysis products conception (POC) routinely performed.Successful cytogenetic achieved 144 cases (84%). Of these, 78 (54%) had aberration. incidence not statistically...
Objective To evaluate the distribution of first- and second-trimester maternal serum markers in twin pregnancy with without pre-eclampsia. Methods One-hundred forty-four 109 unaffected singleton pregnancies were recruited from same institution. First- blood samples stored measured retrospectively for placental growth factor (PlGF), pregnancy-associated plasma protein-A (PAPP-A), free β-human chorionic gonadotropin (β-hCG) α-fetoprotein (AFP). All had measurement first-trimester markers, 167...
Abstract Objective To evaluate the incidence of chromosomal aberrations and clinical outcomes following prenatal diagnosis isolated perimembranous ventricular septal defect (pVSD). Methods This retrospective study was composed a cohort pregnant women whose fetuses were diagnosed with pVSD. Complete examinations fetal heart performed, as well postnatal validation echocardiography follow‐up at 1 year age. The collected data included: spontaneous closure pVSD, need for intervention, outcome....
Introduction: Our objective was to evaluate the incidence of chromosomal aberration (both microscopic and submicroscopic) clinical outcome fetuses with isolated muscular ventricular septal defect (VSD). Material methods: The study included 40 pregnant women whose were diagnosed (mVSD). Of these, 30 patients underwent amniocentesis 10 declined. All samples tested by microarray analysis (CMA). in study, 32 gave birth children retrieved from patients' medical records. Results: who...
This study aims to evaluate the distribution of mean arterial pressure (MAP) and uterine artery Doppler pulsatility index (PI) in first trimester twins with without preeclampsia.A total 147 were recruited from a specialist clinic 110 unaffected singleton pregnancies attending same institution served as controls. MAP PI values expressed multiples gestation-specific median using published equations.Among twins, 12 had preeclampsia two pregnancy-induced hypertension. Among pregnancies, there...
To construct prenatal age-specific reference intervals using ultrasound measurement of total axial length (TAL) in normal fetuses for assessing microphthalmia.Prospective cross-sectional study assessed at a unit between 2011 and 2014. The cohort comprised 309 pregnant women attending routine fetal biometry, viability, or anomaly scan 14 41 weeks gestation. Only singleton viable fetus with anatomy, adequate amniotic fluid, accurate gestational age, no maternal medical complications pregnancy...
Construct a new preeclampsia predicting algorithm in twins.Twins sampled at 10-13 and 16-20 gestational weeks their marker values were log transformed into multiples of the gestation-specific medians (MoMs) for singletons entered logistic regression model with/without prior risk factors.The cohort included 9 PE (18 samples) 96 unaffected cases (175 twin pregnant women. The constructed PlGF, PAPP-A, PP13, Doppler UTPI, MAP with factors generated an area under curve 0.918, 75% detection rate...
<b><i>Introduction:</i></b> The prenatal diagnosis of fetal craniosynostosis is challenging, especially in single-suture cases. When sutures are obliterated, sound waves fail to penetrate the cortical bone, creating an evident acoustic shadow on underlying brain. objective this study was evaluate yield ‘brain shadowing sign' (BSS) as a novel sonographic marker for craniosynostosis. <b><i>Subjects and Methods:</i></b> Patients with antenatal...
Abstract Aims: To determine first trimester maternal serum placental protein 13 (PP13) in singletons vs. twins with and without severe preeclampsia (PE). Methods: Serum samples were prospectively collected at 8–14 weeks of gestation. PP13 was determined by solid-phase immunoassay. Patients recruited community clinics throughout the country, from twin antenatal assessment clinic Assaf Harofeh Medical Center, Zerifin, Israel. Demographics, medical, pregnancy history obtained enrollment....
Objective: To assess fetal abnormalities leading to very late termination of pregnancy (VLTOP) performed after 32 weeks' gestation.Method: The study population included all pregnant women with singleton that underwent VLTOP in our institute because indications between the years 1998 and 2015.Results: Fifty-seven cases (2.0%) were at ≥32 gestation are subjects current study. Our subdivided into four categories according sequence events led decision for VLTOP: (1) No routine prenatal screening...
Tuberous sclerosis complex (TSC) is a neurocutaneous disorder that results from mutations within either the TSC1 gene or TSC2 gene. Diagnosis based on well‐established clinical criteria genetic criteria. We describe an 18‐month‐old boy who presented with seizures and single hypopigmented macule. He did not meet consensus for diagnosis of TSC. Exome sequencing revealed heterozygous mutation (c.5138G>A (p.Arg1713His)) in patient. This alteration was detected his mother as well several other...
Objective This study aimed to compare the associations of crown–rump length (CRL) discrepancy with birthweight discordance in spontaneous versus vitro fertilization (IVF) conceived dichorionic twin pregnancies. Method A computerized retrospective women referred our ultrasonographic unit for nuchal translucency examination between January 1997 and December 2011. The group was subdivided into twins after IVF, non-IVF fertility treatment spontaneously twins. Birthweight defined as a difference...
OpenAI's GPT-4 (artificial intelligence [AI]) is being studied for its use as a medical decision support tool. This research examines accuracy in refining referrals fetal echocardiography (FE) to improve early detection and outcomes related congenital heart defects (CHDs).