A5064161073- Pharmaceutical Economics and Policy
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical industry and healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Antibiotic Use and Resistance
- Pharmaceutical Quality and Counterfeiting
- Pharmacovigilance and Adverse Drug Reactions
- Multiple and Secondary Primary Cancers
- Economic and Financial Impacts of Cancer
- Cervical Cancer and HPV Research
- Cancer Treatment and Pharmacology
- Hormonal and reproductive studies
- Ovarian function and disorders
- Medication Adherence and Compliance
- Global Cancer Incidence and Screening
- Advanced Breast Cancer Therapies
- Ethics in Clinical Research
- Blood Pressure and Hypertension Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Science, Research, and Medicine
- Health and Medical Research Impacts
- Health Sciences Research and Education
- Medical Device Sterilization and Disinfection
- Mobile Health and mHealth Applications
- Healthcare cost, quality, practices
Medical University Pleven
2019-2024
Radboud University Nijmegen
2018
Radboud University Medical Center
2018
Medical University of Sofia
2014-2015
ObjectiveTo develop a consensus-based set of generic competencies in antimicrobial prescribing and stewardship for European prescribers through structured consensus procedure.MethodsThe RAND-modified Delphi procedure comprised two online questionnaire rounds, face-to-face meeting between final review. Our departure point was agreed previously by among UK multi-disciplinary panel, which had been subsequently revised consultation with ESCMID Study Group representatives. The 46 draft competency...
Bulgaria is among the European Union (EU) countries with highest burden of cervical cancers and life expectancy below EU average. The majority cancer cases (more than 95%) are caused by human papillomavirus (HPV). aim this retrospective, cost illness study to identify direct healthcare costs in from payer perspective calculate indirect associated years lost. Costs data were sourced National Health Insurance Fund January 2018 December 2020. Years lost calculated based on country...
The digitization of health systems is a topic immense significance for the modern world. It holds potential to transform delivery healthcare services, enhancing their quality, efficiency, and accessibility. Electronic prescriptions are key element this process, but it crucial ensure implementation protects patients’ personal data privacy. This article examines in Bulgaria, with focus on electronic prescriptions. highlights aspects protection, risks associated misuse, advantages
Ensuring the quality and safety of medicinal products is paramount importance to pharmaceutical industry. Good manufacturing practice (GMP) regulations are part a manufacturer’s management system ensure that manufactured, imported controlled consistently standards appropriate their intended use. The aim present study analyze non-compliant operations identified during GMP inspections carried out by national competent authorities (NCA) in EU/EEC between 2013 2022. A retrospective analysis...
OBJECTIVE: The aim of the present study is to investigate (1) what patients’ attitude towards and (2) preferences use generic medicines in Bulgaria (3) which are main factors influencing their opinion. METHODS: Using pseudo-randomization we select a sample 225 participants, men women from general population, patients community pharmacies. For our survey used standardized self-questionnaire ten points. influence sex, age, education, medical history, knowledge drugs experience with...
The aim of the study was to analyze presence undeclared sildenafil, tadalafil, and vardenafil in food supplements (FSs) for erectile dysfunction. determined using generated ultraviolet (UV)-spectra mass-spectrometry (MS)-spectra as well chromatograms produced by photodiode array (PDA)-detector ion trap MS-detector. results were processed Xcalibur ver. 2.0.7. Fourteen 20 analyzed FSs contained ingredients. Sildenafil present 12 them. Many violations discrepancies between label information...
The aim of the study is to identify current practices self-medication in Bulgaria, estimate extent patients are influenced by information about safety OTC products and pharmacists’ role behavior process. An anonymous, questionnaire-based, descriptive was carried out among 280 pharmacists. majority (92.6%) ask for advice before buying products. Most often need drugs mild conditions (80.7%), save time (63.9%), because they unable consult a physician (61.9%). medium duration consultation an...
<h3>Background and Importance</h3> Polycystic ovary syndrome (PCOS) is a severe public health problem major determinant of various reproductive, metabolic, psychological outcomes. The pharmacological management PCOS complex should be individualised based on the multifactorial manifestation disease in individual patient her reproductive desires. <h3>Aim Objectives</h3> To identify most common drug-related problems (DRPs) by reviewing analysing data from scientific literature treatment...
<h3>Background and Importance</h3> Medication errors (ME) are preventable mistakes or incidents that can occur at any stage of the medication use process, which cause patient harm significant morbidity mortality. <h3>Aim Objectives</h3> Identification nature, incidence, potential preventative measures DRPs. To evaluate role pharmacist in ME risk reduction process to identify critical points outline strategies reduce iatrogenic ME. <h3>Material Methods</h3> The current prospective direct...
The presented article provides a systematic review of the pharmaceutical legislation (EU Pharmaceutical Package) – current proposal European Commission for new Directive, repealing and replacing Directives modifying Regulations Parliament Council, incorporating relevant parts Regulation concerning medicinal products pediatrics, orphan drugs others, aiming at revision in context antimicrobial resistance challenges facing introduction innovative medicines Europe. It outlines critical analysis...
A retrospective, cost-of-illness study aimed at identifying direct healthcare costs of vulvar, vaginal, anal, penile, and H&N cancers in Bulgaria from the payer perspective calculating indirect associated years life lost was carried out. Costs’ data were obtained National Health Insurance Fund January 2018 to December 2020. Years calculated based on country gender-specific expectancy. The human capital approach used evaluate costs. total treatment for 3623 patients EUR 10,875,771 (2018),...
Background and Clinical Significance: Voriconazole is a commonly prescribed second-generation azole used for the prevention treatment of fungal infections. This report seeks to elucidate relationship between certain intravenous infusion parameters causality severity potential visual adverse events associated with voriconazole administration, despite existing reports disturbances such as hallucinations altered perception, underlying causes which remain inadequately understood. Case...
Current retrospective cohort study analyses clinical database records of 4792 assisted reproduction procedures to assess the significance target effectiveness endpoints from a safety perspective.Stimulation protocols with urinary, recombinant or combination both types gonadotrophin preparations are compared according following primary endpoints: incidence ovarian hyperstimulation syndrome (OHSS), cycle cancellation, follicle count, induced estradiol values, pregnancy achieved and cycles...
The goal of this study is to establish the presence or absence anabolic androgenic steroids in food supplements implemented sports practice, assess health risk from intake with quality and content discrepancies conflict recommendations. authors analysed 23 samples by using liquid chromatographic methods. presence/absence substances steroid structure was determined considering resulting chromatograms reference substances. analysis data showed that 11 out did not contain substances, while...