Reinout Naesens
A5073301908- SARS-CoV-2 and COVID-19 Research
- Fungal Infections and Studies
- Antibiotic Resistance in Bacteria
- COVID-19 Clinical Research Studies
- Antifungal resistance and susceptibility
- SARS-CoV-2 detection and testing
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Vector-borne infectious diseases
- Antibiotics Pharmacokinetics and Efficacy
- Advanced Biosensing Techniques and Applications
- Infectious Diseases and Mycology
- Long-Term Effects of COVID-19
- Mosquito-borne diseases and control
- Vibrio bacteria research studies
- Viral Infections and Vectors
- Antimicrobial Resistance in Staphylococcus
- COVID-19 and healthcare impacts
- Microbial infections and disease research
- Dermatological diseases and infestations
- COVID-19 epidemiological studies
- Infection Control and Ventilation
- COVID-19 and Mental Health
- Testicular diseases and treatments
- Health Systems, Economic Evaluations, Quality of Life
Ziekenhuisnetwerk Antwerpen Stuivenberg
2020-2025
KU Leuven
2006-2024
Rega Institute for Medical Research
2024
ZNA Middelheim Hospital
2022
University College London
2018
Jessa Hospital
2010-2012
Antwerp University Hospital
2010-2011
Province of Antwerp
2011
GZA Ziekenhuizen Campus Sint-Augustinus
2008-2009
ObjectiveTo develop a consensus-based set of generic competencies in antimicrobial prescribing and stewardship for European prescribers through structured consensus procedure.MethodsThe RAND-modified Delphi procedure comprised two online questionnaire rounds, face-to-face meeting between final review. Our departure point was agreed previously by among UK multi-disciplinary panel, which had been subsequently revised consultation with ESCMID Study Group representatives. The 46 draft competency...
Coronavirus Disease 2019 (COVID-19) vaccination has resulted in excellent protection against fatal disease, including older adults. However, risk factors for post-vaccination COVID-19 are largely unknown. We comprehensively studied three large nursing home outbreaks (20-35% cases among residents) by combining severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) aerosol monitoring, whole-genome phylogenetic analysis and immunovirological profiling of nasal mucosa digital nCounter...
Three hospitals implemented molecular point-of-care tests (POCTs) to screen patients for SARS-CoV-2 infection upon admission during the 2021/2022 influenza season, which in Belgium lasted from January April 2022. The samples were simultaneously tested A/B. Influenza positivity at was examined relation patient characteristics and symptomatology. POCTs performed on all requiring urgent hospitalization, regardless of reason. A total 9327 included study, 411 (4.4%) positive Asymptomatic mild...
Abstract Background Nakaseomyces glabratus ( Candida gabrata ) poses a significant clinical challenge due to common drug resistance. We report case of complicated urinary tract infection (UTI) progressing prostatitis and urosepsis, with the emergence hyper-multidrug-resistant isolate low stress tolerance, slow growth short life span. This study elucidates genetic mechanisms phenotypic characteristics underlying antifungal hyper-resistance strong fitness trade-offs, explores potential...
Colistin is used as last treatment option for pneumonia associated with multidrug-resistant (MDR) Pseudomonas spp.. Literature about the best administration mode (inhalation versus parenteral treatment) lacking.A retrospective study of 20 intensive care patients a MDR P. aeruginosa receiving colistin sulphomethate sodium (Colistineb®) between 2007 and 2009 was performed. A strain considered if it resistant to at least 6 following antibiotics: piperacillin-tazobactam, ceftazidime, cefepime,...
The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the general population context a relatively high immunity gained through early waves disease 19 (COVID-19), and vaccination campaigns. Despite this context, significant number patients were hospitalized, identifying risk factors associated with era is critical for targeting further preventive, curative interventions. We retrospectively analyzed individual medical records 1501 SARS-CoV-2 positive...
ABSTRACT We conducted a multicentre test‐negative case–control study covering the period from October 2023 to January 2024 among adult patients aged ≥ 18 years hospitalised with severe acute respiratory infection in Europe. provide early estimates of effectiveness newly adapted XBB.1.5 COVID‐19 vaccines against PCR‐confirmed SARS‐CoV‐2 hospitalisation. Vaccine was 49% overall, ranging between 69% at 14–29 days and 40% 60–105 post vaccination. The conferred protection hospitalisation first...
Prolonged shedding of SARS-CoV-2 in immunocompromised patients has been described. Furthermore, an accumulation mutations the genome these observed.We describe viral evolution, immunologic response and clinical course a patient with lymphoma complete remission who had received therapy rituximab remained RT-qPCR positive for 161 days.The hospitalised 10 days, after which he fully recovered asymptomatic. A progressive increase Ct-value, coinciding rise lymphocyte count, was seen from day 137...
Although the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is lasting for more than 1 year, exposition risks of health-care providers are still unclear. Available evidence conflicting. We investigated prevalence antibodies against SARS-CoV-2 in staff a large public hospital with multiple sites Antwerp region Belgium. Risk factors infection were identified by means questionnaire and human resource data. performed hospital-wide serology tests weeks following first...
The colorimetric Vitek 2 YST card and the yeast susceptibility test (AST-YS01) were evaluated for their identification efficacy use in assessing vitro of Candida spp. to fluconazole, voriconazole amphotericin B. Ninety-one percent or 62 68 isolates from blood specimens correctly identified, as compared determinations ITS2 fragment length. overall essential agreements between Sensititre YeastOne (SYO) method 78.4%, 84.6% 90.8%, B, respectively. categorical SYO fluconazole 76.9% 96.9%, poorest...
Abstract Since the onset of coronavirus disease (COVID-19) pandemic in Belgium, UZ/KU Leuven has played a crucial role as National Reference Centre (NRC) for respiratory pathogens, to be first Belgian laboratory develop and implement developed diagnostic assays SARS-CoV-2 (severe acute syndrome 2) later assess quality commercial kits. To meet growing demand decentralised testing, both clinical laboratories government-supported high-throughput platforms were gradually deployed across Belgium....
We conducted a multicentre test-negative case-control study covering the period from October 2023 to January 2024 among adult patients aged ≥18 years hospitalised with severe acute respiratory infection in Europe. provide early estimates of effectiveness newly adapted XBB.1.5 COVID-19 vaccines against PCR-confirmed SARS-CoV-2 hospitalisation. Vaccine was 48% overall, ranging between 68% at 14–29 days and 40% 60–105 post vaccination. The conferred protection hospitalisation first 3.5 months...
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