Laura Heireman

ORCID: 0000-0002-5912-9605
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 detection and testing
  • SARS-CoV-2 and COVID-19 Research
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Bacterial Identification and Susceptibility Testing
  • Diabetes Treatment and Management
  • Antibiotic Resistance in Bacteria
  • Muscle and Compartmental Disorders
  • Urinary Tract Infections Management
  • Parvovirus B19 Infection Studies
  • Pregnancy and Medication Impact
  • COVID-19 Impact on Reproduction
  • Vibrio bacteria research studies
  • Blood transfusion and management
  • COVID-19 epidemiological studies
  • Systemic Lupus Erythematosus Research
  • Mycobacterium research and diagnosis
  • Hemoglobinopathies and Related Disorders
  • Inhalation and Respiratory Drug Delivery
  • Atrial Fibrillation Management and Outcomes
  • Infectious Diseases and Tuberculosis
  • Platelet Disorders and Treatments
  • Immune responses and vaccinations
  • Bacterial biofilms and quorum sensing
  • Antibiotics Pharmacokinetics and Efficacy

AZ Sint-Blasius
2024

Ziekenhuisnetwerk Antwerpen Stuivenberg
2017-2022

Ghent University Hospital
2020-2022

Antwerp University Hospital
2021

AZ Maria Middelares
2019-2020

Committee on Publication Ethics
2020

Prolonged shedding of SARS-CoV-2 in immunocompromised patients has been described. Furthermore, an accumulation mutations the genome these observed.We describe viral evolution, immunologic response and clinical course a patient with lymphoma complete remission who had received therapy rituximab remained RT-qPCR positive for 161 days.The hospitalised 10 days, after which he fully recovered asymptomatic. A progressive increase Ct-value, coinciding rise lymphocyte count, was seen from day 137...

10.3390/v14040752 article EN cc-by Viruses 2022-04-03

Abstract During the last decade, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has revolutionized diagnosis of fungal infections. Recently, a new Conidia ID-fungi plate (IDFP) medium was introduced to facilitate growth and sampling fungi. This study aimed evaluate IDFP for MALDI-TOF MS identification by comparison with standard using two reference libraries. A total 75 filamentous isolates (including 32 dermatophytes) were inoculated on...

10.1093/mmy/myz138 article EN Medical Mycology 2019-12-24

To reduce the inappropriate use of broad-spectrum antibiotics in a 1000+ bed acute tertiary care hospital by introduction cascade antimicrobial susceptibility reporting for Enterobacterales.Over 1-year period, we selectively suppressed to piperacillin-tazobactam (TZP) and meropenem (MEM) Enterobacterales strains susceptible amoxicillin-clavulanic acid (AMC) negative extended-spectrum β-lactamase (ESBL). We measured effects on hospital-wide antibiotic consumption (defined daily doses/1000...

10.1136/ejhpharm-2021-002951 article EN European Journal of Hospital Pharmacy 2022-02-21

Introduction: Frequent causes of high anion gap metabolic acidosis (HAGMA) are lactic acidosis, ketoacidosis and impaired renal function. In this case report, a HAGMA caused by ketones, L- D-lactate, acute failure as well 5-oxoproline is discussed. Case presentation: A 69-year-old woman was admitted to the emergency department with lowered consciousness, hyperventilation, diarrhoea vomiting. The patient had suffered uncontrolled type 2 diabetes mellitus, underwent gastric bypass surgery in...

10.1080/17843286.2017.1358504 article EN Acta Clinica Belgica 2017-07-27

The use of pneumatic tube system (PTS) transport has gained considerable popularity in modern hospitals but is also associated with sample hemolysis. potential contribution PTS-associated acceleration forces to high hemolysis rates observed the emergency department (ED) not been investigated before and can be easily examined nowadays using smartphone applications. first aim our study was investigate whether PTS induces patient samples obtained from ED. We explored a correlation between index...

10.7754/clin.lab.2018.180325 article EN Clinical Laboratory 2018-01-01

α-Thalassemia (α-thal) is a common hemoglobinopathy mainly caused by deletion of one or both α-globin genes. We describe an autochthonous Belgian family diagnosed with α-thal trait. Molecular analysis revealed novel large at least 170 kb between 226.68 (0.2 Mb) and 402.68 (0.4 from the telomere 16p, leaving subtelomeric region intact. The includes genes (HBA1 HBA2) but also flanking possibly related to non hematological effects: HBQ1, LUC7L, ITFG3, RGS11, ARHGDIG, PDIA2 AXIN1. These are not...

10.1080/03630269.2019.1625786 article EN Hemoglobin 2019-03-04

Abstract Introduction Light transmission aggregometry (LTA), used to detect clopidogrel resistance in patients under antiplatelet therapy, is prone multiple variables potentially influencing results and interpretation. Currently, no attention given type of aggregometer or reagent used. The aim this study was evaluate the interassay variability between two aggregometers (Chronolog700 TA‐8V), using different ADP reagents (Chrono‐Par ® Agro‐Bio ADP) therapy. Additionally, LTA were correlated...

10.1111/ijlh.13579 article EN International Journal of Laboratory Hematology 2021-06-15

The high variability of SARS-CoV-2 serological response after COVID-19 infection hampers its use as indicator the timing infection. A potential alternative method is determination affinity maturation IgG, expressed IgG avidity.SARS-CoV-2 concentration and avidity were measured in sera hospitalized patients sampled at two weeks ≥12 post symptom onset using an in-house developed protocol based on EUROIMMUN (anti-spike) EDI™ (anti-nucleocapsid) ELISA protocols.We included 68 confirmed that...

10.1080/17843286.2021.1943231 article EN Acta Clinica Belgica 2021-06-21

Abstract The goal of this study was to estimate rates SARS-CoV-2 carriership and viral loads in the general Antwerp population compare estimated prevalences incidences with governmental data (numbers detected positive cases, stringency measure index) order evaluate dynamics leading second wave. We used (pre)admission screening results from major hospitals for estimating community incidences. 43.545 samples were included (April – November 2020). High (mean week prevalence 1.3%) found...

10.1101/2020.12.09.20246462 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-12-11

Introduction The incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections in the Belgian community is mainly estimated based on test results patients with coronavirus disease (COVID-19)-like symptoms. aim this study was to investigate evolution SARS-CoV-2 reverse transcriptase polymerase chain reaction (RT-PCR) positivity ratio and distribution viral loads within a cohort asymptomatic screened prior hospitalization or surgery, stratified by age category....

10.1371/journal.pone.0259908 article EN cc-by PLoS ONE 2021-11-11

Heireman, Laura PharmD; Vantilborgh, Anna MD; Devreese, Katrien MD, PhD Author Information

10.1097/rhu.0000000000001476 article EN JCR Journal of Clinical Rheumatology 2020-07-09

"Comparison of the positivity rate anti-spike and anti-nucleocapsid SARS-CoV-2 IgG in asymptomatic pregnant women." Journal Obstetrics Gynaecology, 42(5), pp. 1541–1542

10.1080/01443615.2021.1997960 article EN Journal of Obstetrics and Gynaecology 2021-12-27
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