- Bacterial Identification and Susceptibility Testing
- Infection Control in Healthcare
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Sepsis Diagnosis and Treatment
- Salmonella and Campylobacter epidemiology
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Clostridium difficile and Clostridium perfringens research
- Viral gastroenteritis research and epidemiology
- Infective Endocarditis Diagnosis and Management
- Urinary Tract Infections Management
- Emergency and Acute Care Studies
- Infection Control and Ventilation
- Enterobacteriaceae and Cronobacter Research
- Microscopic Colitis
- Central Venous Catheters and Hemodialysis
- Advanced Radiotherapy Techniques
- Pneumonia and Respiratory Infections
- Machine Learning in Healthcare
- Pharmaceutical and Antibiotic Environmental Impacts
- Bayesian Modeling and Causal Inference
- Statistical Methods and Bayesian Inference
- Antibiotics Pharmacokinetics and Efficacy
Statens Serum Institut
2015-2025
Ontario Institute for Cancer Research
2017
University Hospitals Birmingham NHS Foundation Trust
2017
Laboratoire National de Santé
2017
Biology of Infection
2017
Engineering Associates (United States)
2017
Aarhus University Hospital
1999-2016
Copenhagen University Hospital
2010-2012
Environmental Protection Agency
2011
Herlev Hospital
1995-2010
In June-November 2020, SARS-CoV-2-infected mink were detected in 290 of 1,147 Danish farms. North Denmark Region, 30% (324/1,092) people found connected to farms tested SARS-CoV-2-PCR-positive and approximately 27% (95% confidence interval (CI): 25-30) SARS-CoV-2-strains from humans the community mink-associated. Measures proved insufficient mitigate spread. On 4 November, government ordered culling all mink. Farmed constitute a potential virus reservoir challenging pandemic control.
During a period in which vaccination of splenectomized patients has been recommended, we analysed the patterns severe post-splenectomy infections (i.e. bacteraemia or meningitis) defined population-based cohort. A total 561 undergoing splenectomy were identified during 1984-93 Danish county, and 538 eligible followed for 1731 person-years. After splenectomy, 38 contracted bacteraemia, 45% occurred within 30 d postoperative period). No cases meningitis found. Among incidence rate was 2.3 per...
Healthcare-associated infections (HAI) are among the most common adverse events of medical care. Surveillance HAI is a key component successful infection prevention programmes. Conventional surveillance - manual chart review resource intensive and limited by concerns regarding interrater reliability. This has led to development use automated (AS). Many AS systems product in-house efforts heterogeneous in their design methods. With this roadmap, PRAISE network aims provide guidance on how...
The emergence of bloodstream infections (BSI) caused by vancomycin-resistant Enterococci (VRE) has concern. Nonetheless, it remains unclear whether these types are associated with an excess risk severe outcomes when compared vancomycin-susceptible (VSE). This cohort study included hospitalized patients in Denmark
Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen One Health antimicrobial resistance (AMR) surveillance approach.
Healthcare-associated infections (HAI) are a major public health concern. Monitoring of HAI rates, with feedback, is core component infection prevention and control programmes. Digitalization healthcare data has created novel opportunities for automating the surveillance process to varying degrees. However, methods not standardized vary widely between different facilities. Most current automated (AS) systems have been confined local settings, practical guidance on how implement large-scale...
BackgroundWe aimed to test the accuracy of an electronic hand hygiene monitoring system (EHHMS) during daily clinical activities in different wards and with varying health care professions.MethodsThe EHHMS (Sani Nudge) was assessed real conditions by comparing events registered two observers parallel EHHMS. The were categorized as true-positive, false-positive, false-negative registrations. Sensitivity positive predictive value (PPV) calculated.ResultsA total 103 performed 25 workers (9...
We report an outbreak with Salmonella Typhimurium DT104 resistant to six different antibiotic classes. The occurred in Denmark July/August 2005 and was traced a single restaurant. In addition patient interviews, important tool the investigation of this comparison by multi-locus variable number tandem repeat analysis (MLVA) typing strains from food surveillance system. This showed that source imported beef served as carpaccio. Carpaccio, thinly sliced raw fillet beef, has not previously been...
Clostridium difficile is a major cause of nosocomial infectious diarrhoea. Treatment C. infection (CDI) depends on disease severity. A combination vancomycin and metronidazole often recommended in severe cases. The aim this study was to examine, murine model CDI, if mice treated with had better clinical outcome than or alone.C57BL/6J pretreated an antimicrobial mixture were challenged VPI 10463 phosphate-buffered saline by oral gavage. After the challenge, placebo, vancomycin, for 10 days....
We estimated the incidence and mortality of bacteraemia in County North Jutland examined factors that could explain changes observed. A population‐based survey was conducted Danish during 1981–1994. Data were retrieved from a regional register. The determined through linkage to Civil Registration System. total 7198 bacteraemias detected, annual increased 76 per 100,000 person‐years 1981 153 1994. One major determining factor change blood culture system with higher volume sample, but numbers...
Some Aerococcus-like organisms (ALOs) have recently been described in Denmark. The bacteria were originally isolated from the urine of elderly patients with urinary tract infections. Since 1987, we identified 17 cases bacteremia/septicemia which ALOs pure culture blood; report data these cases. Six presented endocarditis, eight urosepticemia, and three septicemia. In all but one reports, was suspected as focus infection, nine patients. All patient had predisposing illnesses; predominantly or...
BACKGROUND In 2015, Denmark launched an automated surveillance system for hospital-acquired infections, the Hospital-Acquired Infections Database (HAIBA). OBJECTIVE To describe algorithm used in HAIBA, to determine its concordance with point prevalence surveys (PPSs), and present trends bacteremia SETTING Private public hospitals METHODS A case was defined as at least 1 positive blood culture pathogen (bacterium or fungus) taken between 48 hours after admission discharge, using Danish...
Background Carbapenemase-producing Escherichia coli are increasing worldwide. In recent years, an increase in OXA-244-producing E. isolates has been seen the national surveillance of carbapenemase-producing organisms Denmark. Aim Molecular characterisation and epidemiological investigation from January 2016 to August 2019. Methods For investigation, data Danish National Patient Registry register civil registration were used together with phone interviews patients. Isolates characterised by...