Brian Kristensen

ORCID: 0000-0003-4359-6142
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About
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Research Areas
  • Bacterial Identification and Susceptibility Testing
  • Infection Control in Healthcare
  • Nosocomial Infections in ICU
  • Antibiotic Use and Resistance
  • Antibiotic Resistance in Bacteria
  • Sepsis Diagnosis and Treatment
  • Salmonella and Campylobacter epidemiology
  • Antimicrobial Resistance in Staphylococcus
  • Streptococcal Infections and Treatments
  • Clostridium difficile and Clostridium perfringens research
  • Viral gastroenteritis research and epidemiology
  • Infective Endocarditis Diagnosis and Management
  • Urinary Tract Infections Management
  • Emergency and Acute Care Studies
  • Infection Control and Ventilation
  • Enterobacteriaceae and Cronobacter Research
  • Microscopic Colitis
  • Central Venous Catheters and Hemodialysis
  • Advanced Radiotherapy Techniques
  • Pneumonia and Respiratory Infections
  • Machine Learning in Healthcare
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Bayesian Modeling and Causal Inference
  • Statistical Methods and Bayesian Inference
  • Antibiotics Pharmacokinetics and Efficacy

Statens Serum Institut
2015-2025

Ontario Institute for Cancer Research
2017

University Hospitals Birmingham NHS Foundation Trust
2017

Laboratoire National de Santé
2017

Biology of Infection
2017

Engineering Associates (United States)
2017

Aarhus University Hospital
1999-2016

Copenhagen University Hospital
2010-2012

Environmental Protection Agency
2011

Herlev Hospital
1995-2010

In June-November 2020, SARS-CoV-2-infected mink were detected in 290 of 1,147 Danish farms. North Denmark Region, 30% (324/1,092) people found connected to farms tested SARS-CoV-2-PCR-positive and approximately 27% (95% confidence interval (CI): 25-30) SARS-CoV-2-strains from humans the community mink-associated. Measures proved insufficient mitigate spread. On 4 November, government ordered culling all mink. Farmed constitute a potential virus reservoir challenging pandemic control.

10.2807/1560-7917.es.2021.26.5.210009 article EN cc-by Eurosurveillance 2021-02-04

During a period in which vaccination of splenectomized patients has been recommended, we analysed the patterns severe post-splenectomy infections (i.e. bacteraemia or meningitis) defined population-based cohort. A total 561 undergoing splenectomy were identified during 1984-93 Danish county, and 538 eligible followed for 1731 person-years. After splenectomy, 38 contracted bacteraemia, 45% occurred within 30 d postoperative period). No cases meningitis found. Among incidence rate was 2.3 per...

10.1080/003655400458811 article EN Scandinavian Journal of Infectious Diseases 2000-01-01

Healthcare-associated infections (HAI) are among the most common adverse events of medical care. Surveillance HAI is a key component successful infection prevention programmes. Conventional surveillance - manual chart review resource intensive and limited by concerns regarding interrater reliability. This has led to development use automated (AS). Many AS systems product in-house efforts heterogeneous in their design methods. With this roadmap, PRAISE network aims provide guidance on how...

10.1016/j.cmi.2021.02.028 article EN cc-by-nc-nd Clinical Microbiology and Infection 2021-06-30

The emergence of bloodstream infections (BSI) caused by vancomycin-resistant Enterococci (VRE) has concern. Nonetheless, it remains unclear whether these types are associated with an excess risk severe outcomes when compared vancomycin-susceptible (VSE). This cohort study included hospitalized patients in Denmark

10.1080/22221751.2024.2309969 article EN cc-by-nc Emerging Microbes & Infections 2024-01-23
Rodolphe Mader Cindy Demay Evelyne Jouvin‐Marche Marie-Cécile Ploy Olivier Barraud and 95 more Sadika Bernard Yohann Lacotte C. Pulcini Jérôme Weinbach Christine Berling Marielle Bouqueau Anton Hlava Claudia Habl Eva Kernstock Reinhild Strauß R Muchl V Buhmann Ann Versporten Anne Ingenbleek Eline Vandael Greet Haelterman Lieven De Raedt Blaženka Hunjak Bojana Raičković Barbora Macková Eva Niklova Helena Žemličková Lucia Hrivňáková Vlastimil Jindrák Brian Kristensen Mikkel Lyndrup Sissel Skovgaard Ute Wolf Sönksen Birgit Aasmäe Jüri Ruut Ljudmila Linnik Olga Sadikova Pille Märtin A Zanuzdana Gülay Kizilkaya-Güneser Nadiya Oezcelik Tim Eckmanns Ageliki Lambrou Flora Kontopidou Maria Papadaki Mariana Tsana Nikos Maroulis Alkiviadis Vatopoulos Emmanouel Papadogiannakis Marietta Kontarini Achilleas Gikas Aimilia Magkanaraki Alessandra Cozza Domenico Martinelli Francesca Fortunato Rosa Prato Anna Maria Marella Annalisa Pantosti Francesca Prestinaci Luca Busani Patrizio Pezzoti Roberta Creti Rosa Maria Martoccia Silvio Brusaferro Aija Vilde Aiva Jakovela Elina Langusa Liga Grudule Madara Grinsteine Uga Dumpis Asta Dambrauskienė Astra Vitkauskienė Daiva Tirvaitė Lukas Cemnalianskis Edita Kazėnaitė Ilma Lozoraitiene Ruta Adomaitiene Ruta Ambrazaitiene Silvija Kiveryte Agniete Maciulaityte Jolanta Kuklytė Justė Petrene Rolanda Valintėlienė Virginija Kanapeckienė Asta Razmiene Brigita Kairienė Giedre Aleksiene Ginreta Valinciute Robertas Petraitis Arjen Elsemulder Ashna Nakched Jasper Claessen Lili Gui Marcel de Kort Rosa Perán Alieke Van Leeuwen Elma Smeets M.G. Mennen Pita Spruijt Robbin Westerhof

Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen One Health antimicrobial resistance (AMR) surveillance approach.

10.1093/jac/dkab462 article EN cc-by-nc Journal of Antimicrobial Chemotherapy 2021-12-03

Healthcare-associated infections (HAI) are a major public health concern. Monitoring of HAI rates, with feedback, is core component infection prevention and control programmes. Digitalization healthcare data has created novel opportunities for automating the surveillance process to varying degrees. However, methods not standardized vary widely between different facilities. Most current automated (AS) systems have been confined local settings, practical guidance on how implement large-scale...

10.1016/j.cmi.2021.02.027 article EN cc-by-nc-nd Clinical Microbiology and Infection 2021-06-30

BackgroundWe aimed to test the accuracy of an electronic hand hygiene monitoring system (EHHMS) during daily clinical activities in different wards and with varying health care professions.MethodsThe EHHMS (Sani Nudge) was assessed real conditions by comparing events registered two observers parallel EHHMS. The were categorized as true-positive, false-positive, false-negative registrations. Sensitivity positive predictive value (PPV) calculated.ResultsA total 103 performed 25 workers (9...

10.1016/j.ajic.2022.06.017 article EN cc-by American Journal of Infection Control 2022-06-19

We report an outbreak with Salmonella Typhimurium DT104 resistant to six different antibiotic classes. The occurred in Denmark July/August 2005 and was traced a single restaurant. In addition patient interviews, important tool the investigation of this comparison by multi-locus variable number tandem repeat analysis (MLVA) typing strains from food surveillance system. This showed that source imported beef served as carpaccio. Carpaccio, thinly sliced raw fillet beef, has not previously been...

10.1017/s0950268807008047 article EN Epidemiology and Infection 2007-03-05

Clostridium difficile is a major cause of nosocomial infectious diarrhoea. Treatment C. infection (CDI) depends on disease severity. A combination vancomycin and metronidazole often recommended in severe cases. The aim this study was to examine, murine model CDI, if mice treated with had better clinical outcome than or alone.C57BL/6J pretreated an antimicrobial mixture were challenged VPI 10463 phosphate-buffered saline by oral gavage. After the challenge, placebo, vancomycin, for 10 days....

10.1136/bmjgast-2015-000038 article EN cc-by-nc BMJ Open Gastroenterology 2015-11-03

We estimated the incidence and mortality of bacteraemia in County North Jutland examined factors that could explain changes observed. A population‐based survey was conducted Danish during 1981–1994. Data were retrieved from a regional register. The determined through linkage to Civil Registration System. total 7198 bacteraemias detected, annual increased 76 per 100,000 person‐years 1981 153 1994. One major determining factor change blood culture system with higher volume sample, but numbers...

10.1111/j.1699-0463.1999.tb01563.x article EN Apmis 1999-03-01

Some Aerococcus-like organisms (ALOs) have recently been described in Denmark. The bacteria were originally isolated from the urine of elderly patients with urinary tract infections. Since 1987, we identified 17 cases bacteremia/septicemia which ALOs pure culture blood; report data these cases. Six presented endocarditis, eight urosepticemia, and three septicemia. In all but one reports, was suspected as focus infection, nine patients. All patient had predisposing illnesses; predominantly or...

10.1093/clinids/21.4.943 article EN Clinical Infectious Diseases 1995-10-01

BACKGROUND In 2015, Denmark launched an automated surveillance system for hospital-acquired infections, the Hospital-Acquired Infections Database (HAIBA). OBJECTIVE To describe algorithm used in HAIBA, to determine its concordance with point prevalence surveys (PPSs), and present trends bacteremia SETTING Private public hospitals METHODS A case was defined as at least 1 positive blood culture pathogen (bacterium or fungus) taken between 48 hours after admission discharge, using Danish...

10.1017/ice.2017.1 article EN Infection Control and Hospital Epidemiology 2017-03-09

Background Carbapenemase-producing Escherichia coli are increasing worldwide. In recent years, an increase in OXA-244-producing E. isolates has been seen the national surveillance of carbapenemase-producing organisms Denmark. Aim Molecular characterisation and epidemiological investigation from January 2016 to August 2019. Methods For investigation, data Danish National Patient Registry register civil registration were used together with phone interviews patients. Isolates characterised by...

10.2807/1560-7917.es.2020.25.18.1900742 article EN cc-by Eurosurveillance 2020-05-07
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