- Vaccine Coverage and Hesitancy
- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Influenza Virus Research Studies
- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- COVID-19 Clinical Research Studies
- Botulinum Toxin and Related Neurological Disorders
- Cervical Cancer and HPV Research
- COVID-19 epidemiological studies
- Virology and Viral Diseases
- COVID-19 and healthcare impacts
- Pneumocystis jirovecii pneumonia detection and treatment
- Esophageal and GI Pathology
- Receptor Mechanisms and Signaling
- Long-Term Effects of COVID-19
- Cerebral Palsy and Movement Disorders
- Bladder and Urothelial Cancer Treatments
- Eosinophilic Esophagitis
- Urinary and Genital Oncology Studies
- Inhalation and Respiratory Drug Delivery
- Advanced Chemical Sensor Technologies
- Hepatitis B Virus Studies
- COVID-19 and Mental Health
- Celiac Disease Research and Management
University of Foggia
2016-2025
University of Bari Aldo Moro
2010-2024
Ospedale Generale Regionale Francesco Miulli
2024
Câmara Municipal de Almada
2024
Ospedali Riuniti di Foggia
2020-2022
University of Bologna
2015-2021
Parthenope University of Naples
2016
University of Naples Federico II
2005-2008
Aims We investigated whether exercise training could promote angiogenesis and improve blood perfusion left ventricular (LV) remodelling of the post-myocardial infarction (MI) failing heart.We also explored contribution ameliorated b-adrenergic receptor signalling function on overall improvement cardiac contractility reserve induced by exercise.Methods results Adult Wistar male rats were randomly assigned to one four experimental groups.Sham-operated post-MI heart failure (HF) housed under...
Vaccination of healthcare workers (HCWs) reduces the risk occupational infections, prevents nosocomial transmission and maintains delivery during outbreaks. Despite European directive national legislation on workers' protection, immunization coverage among HCWs has often been very low. In light Italian National Plan 2012–2014 recommendations, aim this study was to assess levels factors influencing adherence vaccinations needed for in Puglia region, South Italy. The conducted using an...
The present study aimed to explore differences in COVID-19 outcomes between male and female cases the Apulian District of Foggia, Italy.We performed a retrospective epidemiological among all confirmed that occurred Foggia from 29 February 30 June 2020. surveillance data regional registry (GIAVA-COVID) were used.The main outcome measures proportion hospitalisations, virus clearance case fatality rate.A total 1175 (50.7% female; median age: 55 years) identified 131 tests performed....
To date there has been limited head-to-head evaluation of immune responses to different types COVID-19 vaccines. A real-world population-based longitudinal study was designed with the aim define magnitude and duration immunity induced by each four vaccines available in Italy at time this study. Overall, 2497 individuals were enrolled their first vaccination (T0). Vaccine-specific antibody over Comirnaty, Spikevax, Vaxzevria, Janssen Ad26.COV2.S heterologous compared up six months after...
Abstract Background From the initial stages of pandemic in early 2020, COVID-19-related olfactory and gustatory dysfunctions have been widely reported are emerging as one most frequent long-term sequelae SARS-CoV-2 infection. However, data regarding recovery sense smell taste lacking. This study aimed to characterize evolution up year after diagnosis self-reported COVID-19 cases. Methods Based on active surveillance platform Apulia region, Italy, we selected residents Foggia district who...
Abstract Background Respiratory syncytial virus (RSV), a single-stranded RNA virus, is leading cause of hospitalization in infants, especially ≤ 2 months life. In the light new immunization strategies adoption, we described epidemiological and clinical characteristics RSV-associated hospitalizations pediatric neonatal intensive care units Policlinico Foggia Hospital, Apulia Region, Italy. Methods Hospitalized children with laboratory-confirmed RSV infection from 2011 to 2023 were...
AbstractObjectives: To assess the use of extracorporeal shock wave therapy (ESWT) for treatment equinus foot after stroke and to correlate ESWT effect on spastic plantar-flexor muscles with echo intensity Heckmatt scale. Methods: The prospective open-label study examined 23 patients poststroke lower limb spasticity. Adults received one session hypertonic muscles. spasticity, degree passive ankle dorsiflexion, neurophysiological values were evaluated. Before treatment, participants underwent...
Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen One Health antimicrobial resistance (AMR) surveillance approach.
Epidemiological and virological studies have revealed that SARS-CoV-2 variants of concern (VOCs) are emerging globally, including in Europe. The aim this study was to evaluate the spread B.1.1.7-lineage southern Italy from December 2020–March 2021 through detection S gene target failure (SGTF), which could be considered a robust proxy VOC B.1.1.7. SGTF assessed on 3075 samples week 52/2020 10/2021. A subset positive identified Apulia region during period subjected whole-genome sequencing...
The continuous emergence of SARS-CoV-2 variants and subvariants poses significant public health challenges. latest designated subvariant JN.1, with all its descendants, shows more than 30 mutations in the spike gene. JN.1 has raised concerns due to genomic diversity potential enhance transmissibility immune evasion. This study aims analyse molecular characteristics JN.1-related lineages (JN.1*) identified Italy from October 2023 April 2024 evaluate neutralization activity against a subsample...
Cardiac beta-adrenergic receptor (beta-AR) signaling and left ventricular (LV) responses to beta-AR stimulation are impaired with aging. It is shown that exercise blockade have a favorable effect on cardiac vascular in several cardiovascular diseases. In the present study, we examined effects of these two different strategies dysregulation LV inotropic reserve aging heart. Forty male Wistar-Kyoto aged rats were randomized sedentary, (12 wk treadmill training), metoprolol (250...
OBJECTIVE Type 2 diabetes may affect the humoral immune response after vaccination, but data concerning coronavirus disease 19 (COVID-19) vaccines are scarce. We evaluated impact of on antibody to severe acute respiratory syndrome (SARS-CoV-2) vaccination in older residents long-term care facilities (LTCFs) and tested for differences according antidiabetic treatment. RESEARCH DESIGN AND METHODS For this analysis, 555 LTCFs participating GeroCovid Vax study were included. SARS-CoV-2 trimeric...
Abstract Background The aim of this study is to explore the association between celiac disease and menstrual cycle, gestation puerperal disorders. Methods disorders in a sample 62 childbearing age women (15-49 age) was assessed within an town residence matched case-control conducted 2008. Main outcome measures were presence one or more cycle complication during pregnancy. Results (median age: 31.5, range: 17-49) 186 healthy control 32.5, 15-49) interviewed. A higher percentage has been...
Cystic Fibrosis (CF) lung disease is characterized by high levels of cytokines and chemokines in the airways, producing chronic inflammation. Non-invasive biomarkers, which are also specific for inflammatory immune responses, urgently needed to identify exacerbations evaluate therapeutic efficacy. The aim this study association sputum exhaled breath condensate (EBC) biomarker changes with clinical exacerbation response therapy. We studied simultaneous presence concentration twelve growth...
Penile prosthesis implantation is the solution of choice in patients who have failed or present contraindication to use all conservative treatment for erectile dysfunction (ED). Overall, satisfaction rates are high, with more than 80% and partners fully satisfied cosmetic functional result surgery. Chronic postoperative pain, penile shortening, soft hyposensitive glans, pencil like penis syndrome difficulty cycle device represent most common causes patient's dissatisfaction. Satisfaction...
To compare the effectiveness of two procedures increasing botulinum toxin type A effect for wrist and finger flexor spasticity after stroke.A single-blind randomized trial.Seventy patients with upper limb post-stroke spasticity.Adults muscles stroke were submitted to therapy. After treatment, subjects injected randomly divided into groups adhesive taping (Group A) or daily muscle manual stretching, passive articular mobilization fingers, palmar splint B) 10 days. We measured Modified...
Objective. The study aimed to assess the impact of HPV immunization campaigns organizational aspects, characteristics program (vaccination targets and type offer), communicative strategies adopted by four Italian administrative regions on vaccination coverage observed. Methods. From November 2017 March 2018, regional Local Health Units (LHUs) representatives were invited complete an online survey including 54 questions evaluating invite systems, access systems centres, reminder recall...
In Brief Objective: Concerns exist about the risk of endometrial cancer cells spreading into peritoneal cavity after fluid minihysteroscopy. The aim our study was to evaluate 5-year incidence pelvic recurrences in women affected by early-stage carcinoma (stage IA or IB) who did not undergo preoperative hysteroscopy with low pressure (<70 mm Hg) saline uterine distention. Methods: A total 140 were randomized two groups 70 underwent diagnostic minihysteroscopy before surgical staging. Women...