A5058160948- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Dermatological and COVID-19 studies
- COVID-19 diagnosis using AI
- Oral Health Pathology and Treatment
- Pneumonia and Respiratory Infections
- COVID-19 epidemiological studies
- Viral Infections and Vectors
- Antibiotic Resistance in Bacteria
- Herpesvirus Infections and Treatments
- Malaria Research and Control
- Poxvirus research and outbreaks
- Long-Term Effects of COVID-19
- Bacillus and Francisella bacterial research
- Congenital Diaphragmatic Hernia Studies
- Cancer Diagnosis and Treatment
- COVID-19 and Mental Health
- Influenza Virus Research Studies
- Neonatal Respiratory Health Research
- Mosquito-borne diseases and control
- Antibiotic Use and Resistance
- Economic theories and models
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2023-2025
University of Bari Aldo Moro
2019-2023
Mosquito-borne diseases are an emerging threat in Europe. West Nile virus (WNV) is arbovirus commonly transmitted enzootic cycle involving ornithophilic mosquitoes as major vectors. In recent years, global climate change has been identified a significant driver of the increased spread this virus. Italy, outbreaks WNV infection have recorded every year northern Italy. The Apulia region southern Italy was not considered high-risk until 2023, when unexpected increase infections occurred. aim...
Respiratory syncytial virus (RSV) infection is the most common cause of hospitalization in young children. In last 2 years, public health measures aimed at controlling spread SARS-CoV-2 have affected epidemiology and seasonality RSV worldwide. The aim this descriptive retrospective observational study was to describe characteristics children hospitalized with an academic tertiary care hospital Southern Italy 2021. We also investigate seasonal trends from 2017 demographic characteristics,...
Background: Coronavirus disease is a pandemic that has disrupted many human lives, threatening people’s physical and mental health. Each wave struck in different ways, infectiveness-wise mortality-wise. This investigation focuses on critically ill patients affected by the last two variants, Delta Omicron, aims to analyse if any difference exists between groups. Methods: intensive care unit (ICU) COVID-19 consecutive admissions 1 October 2021 31 March 2022 were recorded daily, data concerning...
Epidemiological and virological studies have revealed that SARS-CoV-2 variants of concern (VOCs) are emerging globally, including in Europe. The aim this study was to evaluate the spread B.1.1.7-lineage southern Italy from December 2020–March 2021 through detection S gene target failure (SGTF), which could be considered a robust proxy VOC B.1.1.7. SGTF assessed on 3075 samples week 52/2020 10/2021. A subset positive identified Apulia region during period subjected whole-genome sequencing...
The recent worldwide spread of New Delhi metallo-beta-lactamase-producing Klebsiella pneumoniae (NDM-KP) in health-care settings remains a concern. aim the study was to describe an outbreak extensively drug-resistant ST147 NDM-1-KP Apulia region Southern Italy that occurred between 2020 and 2022 through genomic surveillance carbapenem-resistant Enterobacterales.
HIV testing is crucial towards the control of Acquired Immune Deficiency Syndrome (AIDS) epidemic. Monitoring trends human immunodeficiency virus (HIV) over time may help interpret incidence new diagnoses and effectiveness strategies. We started a research project aimed at assessing rates for infection among Italian outpatients in 2018–2023. Numeric data screening, confirmatory, monitoring tests obtained by national register were compared with numbers adult residents, newly diagnosed...
The ongoing outbreak of the Monkeypox virus (MPXV) is characterized by sustained human-to-human transmission, particularly among men who have sex with (MSM). aim study was to describe characteristics MPXV infection identified in Southern Italy. Clinical samples for each suspected case from 1 June August 2022 were tested MPXV, and whole-genome sequencing (WGS) performed on two strains. Ten cases identified: eight young adult males, including six MSMs, female. Nine subjects reported recent...
Abstract Background Bronchiolitis is a major cause of hospitalization in infants, particularly the first six months life, with approximately 60–80% admissions due to respiratory syncytial virus (RSV) infection. Currently, no prophylactic options are available for healthy infants. The present study aimed at describing demographic, clinical, and epidemiological characteristics infants hospitalized bronchiolitis Apulia region Italy 2021. Methods From January December 2021, data on children aged...
Abstract Background RT-PCR test for identification of viral nucleic acid is the current standard diagnostic method diagnosis COVID-19 disease but technical reasons limit utilization this assay onlarge scalescreenings. Method We verified in a consecutive series 191 symptomatic patients clinical information that new rapid serological colorimetric qualitatively analyzing IgM/IgG expression can provide with respect to and outcome patients. Results Rapid showed sensitivity 30% specificity 89%...
Background Real-time polymerase chain reaction (RT-PCR) testing for the identification of viral nucleic acid is current standard diagnosis SARS-CoV-2 infection, but technical issues limit its utilization large-scale screening. Serological immunoglobulin M (IgM)/IgG has been proposed as a useful tool detecting exposure. Objective The objective our study was to compare results rapid serological VivaDiag test SARS-CoV-2–related IgM/IgG detection with those RT-PCR laboratory identifying acid....
Differences in the demographic and clinical characteristics of patients infected with Alpha Delta SARS-CoV-2 variants concern a large region Southern Italy were assessed. Two cohorts positive compared. The group consisted 11,135 subjects diagnosed between 21 March April 2021, 499 July August 2021. A descriptive statistical analysis two groups was performed. proportion mild moderate infections significantly higher than (p < 0.001). In fully vaccinated patients, symptomatic individuals group....
The Omicron variant of concern (VOC), first detected in Italy at the end November 2021, has since spread rapidly, despite high vaccine coverage Italian population, especially healthcare workers (HCWs). This study describes an outbreak SARS-CoV-2 infection 15 booster-vaccinated HCWs. On 16 December two HCWs working same ward were infected with SARS-CoV-2. VOC was suspected due to S gene target failure on molecular testing. Further investigation revealed that (65%) 23 attending a social...
Shiga toxin-producing Escherichia coli (STEC) infections result in a significant public health impact because of the severity disease that, young children especially, can lead to hemolytic–uremic syndrome (HUS). A rise number HUS cases was observed Apulia region Italy from 2013 2017, and so, 2018, symptom-based surveillance system for with bloody diarrhea (BD) initiated order detect manage STEC infections. The objective study describe epidemiology June 2018 August 2019. Children <15 years...
Human astroviruses (AstVs) are usually associated with acute gastroenteritis. In recent years, atypical animal-like AstVs have been identified, but their pathogenic role in humans has not determined. Starting from 2010, there a growing evidence that may also be encephalitis human and animal hosts. Some AstV strains (VA1, MLB1/MLB2) display neurotropic potential, as they repeatedly identified patients AstV-related encephalitis, chiefly immunosuppressed individuals. this study, VA1-like was...
Abstract Background Vector-borne diseases (VBDs) represent an emerging global threat to public health due the geographical expansion of arthropod vectors. The study aims assess seroprevalence selected vector-borne pathogens (VBPs) in different groups outdoor workers and occupational risk factors for exposure bites. Methods A cross-sectional was conducted on 170 recruited two regions southern Italy, including farmers, forestry workers, veterinarians, geologists/agronomists administrative...
The coding-complete sequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was obtained from a sample 25-year-old female returning to the Apulia region Italy England. characterized strain showed all spike protein mutations defining SARS-CoV-2 VUI 202012/01, as well other in and genomic regions.
Oral lesions received increased attention as likely new signs or secondary manifestations of COVID-19. Therefore, we clinically examined oral cavity patients with COVID-19 and investigated patient comorbidities possible risk factors disease outcome.
Since its initial detection, the SARS-CoV-2 Omicron sublineage BA.2 has been spreading rapidly worldwide. The aims of this study were to describe first 284 patients infected with variant concern (VOC) in Apulia region southern Italy and assess differences demographic clinical characteristics BA.1 variants. patients, as well information about symptoms, vaccinations hospitalizations for COVID-19, collected. A subset samples from was subjected whole-genome sequencing. 175 compared. proportion...
RSV infection causes severe respiratory illness and mortality in the elderly, especially presence of comorbidities. Early identification would result appropriate clinical-therapeutic management, avoiding hospitalizations, risk healthcare-associated infections, inappropriate antibiotic prescriptions, thus reducing healthcare costs fighting antimicrobial resistance. The aim this study was to assess hospitalizations subjects >64 years hospitalized a large tertiary care hospital Southern...
At the beginning of coronavirus-2019 (COVID-19) pandemic, Italy was one most affected countries in Europe. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is less frequent and severe children than adults. This study analyzed frequency SARS-CoV-2 among all aged <18 years Apulia region southern characteristics infected children. Clinical demographic data were collected through national platform for COVID-19 surveillance. Of 166 region, 104 (62.6%) asymptomatic, 37...
Yearly influenza epidemics have considerable effects on public health worldwide. The 2017-2018 season in Italy was of greater severity than previous seasons. aim this study to describe the Southern and molecular characteristics circulating viral strains.The incidence influenza-like illness (ILI) analysed. Nasopharyngeal swabs collected from patients with ILI week 46/2017 17/2018 were tested identify A viruses (IAV) B (IBV). Sequencing phylogenetic analysis haemagglutinin genes also performed...