A5027081550- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Hepatitis C virus research
- HIV-related health complications and treatments
- Reproductive tract infections research
- Syphilis Diagnosis and Treatment
- Blood donation and transfusion practices
- HIV/AIDS Impact and Responses
- HIV/AIDS drug development and treatment
- Adolescent Sexual and Reproductive Health
- Hepatitis B Virus Studies
- Tuberculosis Research and Epidemiology
- Cervical Cancer and HPV Research
- Data-Driven Disease Surveillance
- Sex work and related issues
- Migration, Health and Trauma
- Pediatric health and respiratory diseases
- COVID-19 epidemiological studies
- HIV, TB, and STIs Epidemiology
- Herpesvirus Infections and Treatments
- Census and Population Estimation
- Italian Social Issues and Migration
- Congenital Ear and Nasal Anomalies
- Female Genital Mutilation/Cutting Issues
Istituto Superiore di Sanità
2011-2023
Regione Puglia
2011
University of Naples Federico II
1996
Federico II University Hospital
1993
In Western Europe, about 50% of newly diagnosed HIV-positive individuals are at a late stage disease and enter in care (i.e. with CD4 count ≤350 μL/μL). The aim the present study is to analyze characteristics factors associated being or an advanced among persons new HIV diagnosis Italy, period 2010-2011.We used individual data on diagnoses reported by surveillance system 2010 2011. Persons cells/μL AIDS (regardless cell count) were defined as presenters (LP); ≤ 200 presenting (AHD).Of 7,300...
Non-AIDS-defining cancers (non-ADCs) have become the leading non-AIDS-related cause of death among people with HIV/AIDS. We aimed to quantify excess risk cancer-related deaths Italian AIDS (PWA), as compared without (non-PWA).A nationwide, population-based, retrospective cohort study was carried out 5285 PWA, aged 15-74 years, diagnosed between 2006 and 2011. Date multiple-cause-of-death data were retrieved up December Excess mortality, non-PWA, estimated using sex- age-standardized...
The rheological properties of blood play an important role in regulating flow micro and macro circulation. In thalassemia syndromes red cells exhibit altered hemodynamic that facilitate microcirculatory diseases: increased aggregation reduced deformability, as well a marked increase adherence to the vascular endothelial cells. A personalized approach treating patients (transfusions, iron chelation, splenectomy), has patients' life expectancy, however they generally present many complications...
HIV testing is crucial towards the control of Acquired Immune Deficiency Syndrome (AIDS) epidemic. Monitoring trends human immunodeficiency virus (HIV) over time may help interpret incidence new diagnoses and effectiveness strategies. We started a research project aimed at assessing rates for infection among Italian outpatients in 2018–2023. Numeric data screening, confirmatory, monitoring tests obtained by national register were compared with numbers adult residents, newly diagnosed...
In 2001, the criteria for blood donor eligibility in Italy were modified by a ministerial decree from permanent deferral "men who have sex with men" to an individual risk assessment of sexual behaviours. The aim this study was evaluate impact change screening on human immunodeficiency virus epidemic among donors Italy.We used data obtained Italian epidemiological surveillance system. We compared collected 2009 and 2010, when policy applied, 1999 applied men based declaration orientation....
BACKGROUND: Estimating the risk of transfusion‐transmitted infections (TTIs) is essential for monitoring blood safety. The residual TTI was estimated nearly 90 percent supply in Italy. STUDY DESIGN AND METHODS: Data were analyzed from 1,079,281 repeat donors, corresponding to 5,361,000 donations made transfusion centers throughout Italy period 1999 through 2001. human immunodeficiency virus (HIV), hepatitis C (HCV), and B (HBV) with incidence rate–window model. denominator rate (i.e., number...
The development of assays for detecting recent HIV infections has become crucial analyzing trends in infection different populations, both surveillance and prevention activities. anti-HIV avidity index (AI), measured with third-generation immunoassays (which detect antibody), been shown to be an accurate tool discriminating (<6 months) from established (≥ 6 months). We compared a immunoassay (AxSYM 1/2 gO; Abbott Diagnostics) fourth-generation (Architect Ag/Ab Combo; Diagnostics; which...
To estimate the size and characteristics of undiagnosed HIV population in Italy 2012 applying a method that does not require surveillance data from beginning epidemic.We adapted known as 'London 2'; is estimated ratio between annual number simultaneous HIV/clinical AIDS diagnoses expected progression rate to clinical population; latter using CD4⁺ cell count distribution asymptomatic patients reported surveillance. Under-reporting/ascertainment new was also considered. Also, total people...
Globally, the HIV epidemic continues to represent a pressing public health issue in Europe and elsewhere. There is an emerging progressively urgent need harmonise STI behavioural surveillance among MSM across European countries through adoption of common indicators, as well development trend analysis order monitor HIV-STI over time. The Sialon II project protocols have been elaborated for purpose implementing large-scale bio-behavioural survey line with Second Generation Surveillance System...
Objective . To estimate the HIV prevalence and number of people living with (PLHIV) in Italy a projection for 2020. Methods Two methods elaborated by Joint United Nations Programme on HIV/AIDS (UNAIDS) were used: Estimate Projection Package Spectrum. Results A total 123,000 (115,000–145,000) individuals aged 15 or more estimated to be at end 2012 was 0.28 (0.24–0.32) per 100 residents more. In 2012, new infections among adults 3,000 (2,700–4,000), need ART 93,000 (80,000–110,000). The...
Background The assumption that migrants acquire human immunodeficiency virus (HIV) before migration, particularly those from high prevalence areas, is common. Aim We assessed the place of HIV acquisition diagnosed in four European countries using surveillance data. Methods Using CD4+ T-cell count trajectories modelled to account for seroconversion bias, we estimated infection year newly HIV-diagnosed residing United Kingdom (UK), Belgium, Sweden and Italy with a known arrival at diagnosis....
We estimated the prevalence of HIV, HBV and HCV infections among injecting noninjecting drug users treated within public drug-treatment centres in Italy to determine correlates infection. In sample 1330 users, HIV was 14.4% injectors 1.6% non-injectors; 70.4% 22.8% non-injectors 83.2% 22.0% non-injectors. Old age, unemployment, intravenous use were significantly correlated with each infections, as well a longer history use. The results indicate that these continue circulate highlighting need...
Despite the procedures adopted for selection of blood donors, in Italy HIV prevalence per 100 000 repeat tested donors (RTD) and first-time (FTD) is high compared to most other Council Europe member states. To evaluate effectiveness predonation procedures, we studied both characteristics undisclosed risk behaviours HIV-positive donors.We analysed data from Italian donor surveillance system 2009, 2010 2011. Based on postdonation interview, were classified by behaviour (heterosexual, MSM,...
In 2006 we conducted a cross-sectional study involving hospital clinical centres in five Italian cities to compare the sexual behaviour of HIV-positive MSM (men who have sex with men) before and after diagnosis HIV infection. Each centre was asked enrol 30 persons aged ≥ 18 years. The questionnaire administered 143 on average 9 years diagnosis. After there decrease number partners: percentage reported having had more than 2 partners decreased from 95.8% 76.2% diagnosis, significant never (or...
Multiple cause-of-death (MCOD) data allow analyzing the contribution to mortality of conditions reported on death certificate that are not selected as underlying cause death. Using MCOD data, this study aimed fully describe cause-specific people with AIDS (PWA) compared without AIDS.We conducted a nationwide investigation based certificates 2,515 Italian PWA and 123,224 who had died between 2006 2010. The most frequently associated mortality, AIDS, were identified using an age-standardized...
In 2012, we conducted a retrospective cross-sectional study to assess the number of people living with HIV linked care and, among these, on antiretroviral therapy. The health authority in each 20 Italian Regions provided list Public Infectious Diseases Clinics providing therapy and monitoring infection. We asked every Clinic report HIV-positive diagnosed those during 2012. 94,146 were reported. majority males (70.1%), Italians (84.4%), aged between 25 49 years (63.4%); probable route...
The safety of blood with regards to transmission infectious diseases is guaranteed by European laws that regulate both the selection donors through pre-donation questionnaires and serological screening. However, variability in epidemiology human immunodeficiency virus (HIV) infection different countries some differences can influence efficacy (with blood) these processes. In this study we compared prevalence HIV donations three macro-areas Europe various western countries, analysed criteria...
Introduction. In industrialized countries, the availability of highly active antiretroviral therapy (HAART) caused a slow but substantial ageing AIDS epidemic mainly due to longer survival persons with HIV/AIDS which has turned HIV into manageable, chronic disease. The number older people is growing in many European countries. We described impact among aged 50 years or more Italy and compared characteristics these cases those diagnosed at an age younger than 50. Methods. source data was...
We estimated the prevalence of HIV, HBV and HCV infections among injecting noninjecting drug users treated within public drug-treatment centres in Italy to determine correlates infection.In sample 1330 users, HIV was 14.4% injectors 1.6% non-injectors; 70.4% 22.8% non-injectors 83.2% 22.0% non-injectors.Old age, unemployment, intravenous use were significantly correlated with each infections, as well a longer history use.The results indicate that these continue circulate highlighting need...
Despite the dramatically improved survival due to combination antiretroviral therapies (cART), life expectancy of people with HIV/AIDS remains lower than that general population. This study aimed estimate, at a population level, experience Italian AIDS (PWA) and quantify prognostic role selected factors diagnosis in risk early mortality (i.e., within six months from diagnosis).A population-based, retrospective-cohort was conducted among PWA diagnosed between 1999 2009 recorded national...