- Infrared Thermography in Medicine
- Viral-associated cancers and disorders
- Syphilis Diagnosis and Treatment
- HIV Research and Treatment
- Cutaneous Melanoma Detection and Management
- Reproductive tract infections research
- Parvovirus B19 Infection Studies
- Systemic Sclerosis and Related Diseases
- Cervical Cancer and HPV Research
- thermodynamics and calorimetric analyses
- Psoriasis: Treatment and Pathogenesis
- Glycosylation and Glycoproteins Research
- melanin and skin pigmentation
- Growth Hormone and Insulin-like Growth Factors
- Nonmelanoma Skin Cancer Studies
- Thermography and Photoacoustic Techniques
- Dermatology and Skin Diseases
- Medicine and Dermatology Studies History
- HIV/AIDS Research and Interventions
- Cytomegalovirus and herpesvirus research
- Thyroid Disorders and Treatments
- Colorectal and Anal Carcinomas
- vaccines and immunoinformatics approaches
- Skin Protection and Aging
- Immunotherapy and Immune Responses
University of Rome Tor Vergata
2017-2024
Hôpital Pontchaillou
2024
Royal Children's Hospital
2024
Stago (France)
2023
McMaster University
2023
San Gallicano Hospital
2006-2015
Sapienza University of Rome
2014-2015
Istituti di Ricovero e Cura a Carattere Scientifico
2003-2013
Istituti Fisioterapici Ospitalieri
2009
Istituto Superiore di Sanità
2008
From February 1983 to January 1985, 497 patients with advanced breast cancer were randomly allocated receive either epirubicin or doxorubicin in the following combination chemotherapy regimen: fluorouracil (5-FU) 500 mg/m2 intravenous (IV) on days 1 and 8; 50 IV day 1; cyclophosphamide (FEC FAC). Cycles repeated every 21 until progression cumulative doses of 700 for 550 doxorubicin. Dose reductions applied according standard criteria. Activity was evaluated 443 (222 FEC arm 221 FAC arm). The...
Abstract Developing efficient wide‐bandgap perovskites is critical to exploit the benefits of a multi‐absorber solar cell and engineering commercially attractive tandem cells. Here, robust, additive‐free, methylammonium‐free triple halide composition for fabrication close‐to‐ideal (1.64 eV) reported. The introduction low percentages chloride into perovskite layer avoided photoinduced segregation lead an evident improvement in crystallization process, reaching enhanced open‐circuit voltages...
Three hundred seventy-nine individuals [137 non-injecting drug using (non-IDU) heterosexuals, 130 homosexual men and 112 IDU] attending the human immunodeficiency virus (HIV) testing program of a sexually transmitted disease (STD) clinic in Rome were studied to estimate prevalence identify modalities transmission herpesvirus-8 (HHV-8) infection. Serological analysis was performed by an immunofluorescence assay able detect anti-latent anti-lytic HHV-8 antibodies. Twelve acquired syndrome...
The outdoor performance monitoring of emerging photovoltaic technologies such as organic or perovskite solar modules in real-life environmental conditions for an extended period will set the grounds further technology’s...
Literature data report an association between some vitamin D receptor (VDR) polymorphisms and different kinds of tumours, including malignant melanoma (MM). Only three VDR (FokI, TaqI A-1012G) have been investigated in with the presence cutaneous MM or development metastases.The present paper analyses for first time BsmI polymorphism prevalence together Breslow thickness. In addition, FokI single nucleotide was also determined.One hundred one patients 101 healthy donors matched age sex were...
ABSTRACT Infection by human herpesvirus 8 (HHV-8) is associated with the development of Kaposi’s sarcoma (KS). Since regression KS can be achieved treatment patients alpha interferon (IFN-α), we analyzed effects IFN-α or anti-IFN-α antibodies (Ab) on HHV-8 latently infected primary effusion lymphoma-derived cell lines (BCBL-1 and BC-1) peripheral blood mononuclear cells (PBMC) from all forms at-risk subjects. inhibited in a dose-dependent manner amplification DNA BCBL-1 induced to lytic...
We have previously reported that patients with active vitiligo (AVP) elevated urinary levels of catecholamine metabolites, such as homovanillic and vanilmandelic acids, irrespective the form disease (acrofacial, segmental, generalized). suggested abnormal release catecholamines from autonomic nerve endings might play an etiological role in onset development through overproduction toxic (oxy)radicals microenvironment melanocytes affected areas. In present study we investigated whether this...
Calcifying epithelioma of Malherbe, or Pilomatricoma, is considered an uncommon cutaneous neoplasia, normally occurring in children as a solitary, firm, asymptomatic, hard, subcutaneous, slowly growing nodule on the face, neck, proximal upper extremity. In literature, two Pilomatricoma ultrasound patterns are described: totally calcified and hypoechoic with internal calcific foci. High frequency has not yet been applied for routine diagnosis Pilomatricoma. The aim study was to...
The native HIV-1 Tat protein was chosen as a vaccine candidate based on its key role in the virus life cycle and correlation of Tat-specific immune responses with asymptomatic stage lower disease progression rates, but also due to sequence conservation amongst various HIV clades well adjuvant effects dendritic cells. Safety, immunogenicity efficacy data monkeys support development this concept.
Impairment of capillaries permeability and changes microcirculation are associated with inflammatory arthritis. In order to demonstrate microvascular differences between psoriatic arthritis (PsA) rheumatoid (RA) we analyzed capillaroscopic abnormalities such as megacapillaries, haemorrhages, ramifications, avascular areas in patients affected by these two rheumatic disorders. Moreover identify specific capillaroscopy patterns the following parameters: venous limb diameter, arterial capillary...
The present prospective study was aimed at evaluating the long-term efficacy of local electrochemotherapy (ECT) with intravenous administration bleomycin, on disease progression and viral activity in classic Kaposi's sarcoma (cKS), a vascular tumor related to human herpes virus-8 infection. Eighteen patients affected by isolate or multiple cutaneous lesions, refractory conventional treatments, although absence visceral involvement, were enrolled study. Follow-up visits performed after 4...
Neisseria gonorrhoeae is the etiological agent of gonorrhoea, an infectious disease characterized by acute inflammation urogenital tract with a massive infiltration neutrophils. Polymorphonuclear leukocyte recruitment one activities recently described interleukin-17A (IL-17A); thus, we analyzed serum concentration IL-17A, together IL-23 and interferon-γ (IFN-γ), in 27 patients gonorrhoea. The these cytokines patients' sera was significantly higher than that detected healthy controls inverse...
The incidence of anal cancer, a Human Papillomavirus (HPV)-related neoplasia, has been increasing in recent decades, mainly men who have sex with (MSM). Cytological changes the epithelium induced by HPV can be detected through an pap smear. This study aimed to evaluate prevalence and epidemiological correlates cytological abnormalities among relatively young MSM at risk for HIV-1 infection, help clarify whether or not this population deserves further investigation assess presence cancer...
Background . The therapeutic management of psoriasis includes conventional treatments as well the new generation highly effective TNF- α inhibitors. However, has proven to be a complex challenge and treatment failures are not uncommon. Thus, laboratory biomarkers disease progression/therapeutic efficacy may greatly help in clinical psoriasis. Aims To identify for monitoring Methods An observational study performed on 59 patients, presenting moderate severe psoriasis, undergoing with...