A5044778778- Neonatal and Maternal Infections
- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Breastfeeding Practices and Influences
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Sepsis Diagnosis and Treatment
- Streptococcal Infections and Treatments
- Antibiotic Use and Resistance
- Child Nutrition and Feeding Issues
- Maternal and Neonatal Healthcare
- Pediatric Hepatobiliary Diseases and Treatments
- Birth, Development, and Health
- Cardiac Structural Anomalies and Repair
- Preterm Birth and Chorioamnionitis
- Cardiac Health and Mental Health
- Bacterial Infections and Vaccines
- Ocular Infections and Treatments
- Pregnancy-related medical research
- Nursing care and research
- Urinary Tract Infections Management
- Material Properties and Processing
- Venous Thromboembolism Diagnosis and Management
- Advances in Oncology and Radiotherapy
- Cystic Fibrosis Research Advances
Ospedale Generale Regionale Francesco Miulli
2008-2025
Clinica Universidad de Navarra
2001-2016
Abstract Background The COVID-19 pandemic has posed several challenges to the provision of newborn nutrition and care interventions including maternal support, breastfeeding family participatory care. Italy was first country be exposed SARS-CoV-2 in Europe. One measures adopted by Italian government during total lockdown cities with complete confinement at home. We aimed examine impact caused on exclusive non-infected mothers. Methods prospectively enrolled 204 mother-baby dyads (9 March 8...
BackgroundEarly aggressive parenteral nutrition (PN), consisting of caloric and nitrogen intake soon after birth, is currently proposed for the premature baby. Some electrolyte disturbances, such as hypophosphatemia hypercalcemia, considered unusual in early life, were recently described while using this PN approach. We hypothesize that, due to its impact on cell metabolism, initial amino acid (AA) amount may specifically influence metabolism phosphorus, consequently calcium. aim evaluate AA...
Global assessment of antimicrobial agents prescribed to infants in the neonatal intensive care unit (NICU) may inform stewardship efforts.We conducted a one-day global point prevalence study all antimicrobials provided NICU infants. Demographic, clinical, and microbiologic data were obtained including level, census, birth weight, gestational/chronologic age, diagnoses, therapy (reason for use; length therapy), program (ASP), 30-day in-hospital mortality.On July 1, 2019, 26% (580/2,265;...
Appropriate use of antibiotics is life-saving in neonatal early-onset sepsis (EOS), but overuse associated with antimicrobial resistance and long-term adverse outcomes. Large international studies quantifying early-life antibiotic exposure along EOS incidence are needed to provide a basis for future interventions aimed at safely reducing exposure.To compare early postnatal antibiotics, EOS, mortality among different networks high-income countries.This retrospective, cross-sectional study...
<i>Background:</i> Several reports indicate a decreased cortisol response to adrenocorticotropic hormone in preterm infants developing chronic lung disease and with refractory hypotension. Low-dose hydrocortisone (HC) may allow for beneficial effects. <i>Objective:</i> Our aim was assess whether HC is able increase survival without disease. <i>Methods:</i> We performed double-blind, randomized, placebo-controlled trial. Fifty mechanically ventilated (birth...
Abstract Background Bronchiolitis is a major cause of hospitalization in infants, particularly the first six months life, with approximately 60–80% admissions due to respiratory syncytial virus (RSV) infection. Currently, no prophylactic options are available for healthy infants. The present study aimed at describing demographic, clinical, and epidemiological characteristics infants hospitalized bronchiolitis Apulia region Italy 2021. Methods From January December 2021, data on children aged...
Abstract Background Early-life antibiotic exposure is disproportionately high compared to the burden of culture-proven early-onset sepsis (CP-EOS). We assessed contribution culture-negative cases overall in first postnatal week. Methods conducted a retrospective analysis across eleven countries Europe, North America, and Australia. All late-preterm term infants born between 2014 2018 who received intravenous antibiotics during week were classified as treated for ≥5 days (CN ≥ 5d), <5 <...
Probiotic administration has become common practice in neonatal intensive care units (NICUs) to prevent necrotizing enterocolitis (NEC) and promote gut health preterm infants. While probiotics are generally considered safe, rare cases of probiotic-related sepsis have been reported. We present a case Lactobacillus rhamnosus infant, highlighting the challenges involved its diagnosis. The infant developed symptoms on 13th day probiotic treatment. Laboratory analyses, including MALDI-TOF,...
Background: Antimicrobial therapies used for treating group B streptococcus (GBS) early-onset sepsis (EOS) provide insight into clinicians’ adherence to antimicrobial stewardship (AMS) guidelines. Methods: We reviewed given treat newborns with GBS-EOS. Data were obtained from an Italian surveillance network (including 35 birthing centers) and prospectively collected 1 January 2003 31 December 2024. Empiric definitive classified as adequate inadequate. Results: There 967,054 live births 200...
We evaluated renal function in early childhood 48 very low birthweight (VLBW) ex-preterms and correlated the perinatal risk factors for acute failure (ARF) postnatal growth course to abnormal findings at children-age. Nineteen boys 29 girls (6.3 8.2 years of age) had a physical examination, exploration function, ultrasound. Cases were compared with age-matched controls that born full term. All patients normal blood pressure, ultrasound, kidney length body height. Plasma creatinine clearance...
Background: To evaluate the rates of lumbar puncture (LP) in infants with culture-proven sepsis. Study design: We prospectively enrolled 400 early- or late-onset sepsis due to Group B streptococcus (GBS) Eschericha coli, diagnosed within 90 days life. Rates LP and potential variables associated performance were evaluated. Moreover, cerebrospinal fluid (CSF) characteristics results molecular analysis investigated. Results: was performed 228/400 (57.0%) infants; 123/228 LPs (53.9%) after...
The effectiveness of “inadequate” intrapartum antibiotic prophylaxis (IAP administered < 4 h prior to delivery) in preventing early-onset sepsis (EOS) is debated. Italian prospective surveillance cohort data (2003–2022) were used study the type and duration IAP according timing symptoms onset group B streptococcus (GBS) E. coli culture-confirmed EOS cases. was defined “active” when pathogen yielded cultures susceptible. We identified 263 cases (GBS = 191; 72). Among GBS EOS, 25% had...
Abstract We retrospectively investigated mother-to-infant transmission of group B Streptococcus (GBS) in 98 cases late-onset disease reported during 2007–2018 by a network Italy. Mothers with full assessment vaginal/rectal carriage tested at prenatal screening and time late onset (ATLO) were included. Thirty-three mothers (33.7%) never GBS colonized; 65 (66.3%) colonized, which 36 (36.7%) persistently colonized. colonization ATLO had high rates bacteriuria (33.9%) positive breast milk...
Exclusive breastfeeding during postpartum hospitalization is very important for ensuring the success of at home. The aim study to determine if on-site nurse in rooming improves exclusive ratio.
Background: Exclusively breastfeeding your newborn while in the hospital is imperative for suc-cessful at home. This study will investigate if having a nurse on-site during rooming-in can enhance proportion of exclusive breastfeeding. Methods: We carried out prospective cohort to assess first three months life among two Neona-tology Units Southern Italy with different settings. The Ente Ecclesiastico Miulli Ac-quaviva delle Fonti had nurses available 24/7 (on-site group), Policlinico Bari on...
La Chlamydia pneumoniae causa infecciones respiratorias y se transmite tanto por vía aérea como a través de fomites. Es probablemente más frecuente lo descrito hasta el momento, debido al gran número casos asintomáticos oligo-sintomáticos. El tratamiento basa en la utilización macrólidos, tetraciclinas quinolonas, aunque recuperación puede ser lenta. Estudios multicéntricos revelan un aumento incidencia neumonías causadas ésta bacteria, siendo incluso que Streptoccocus Mycoplasma pneumoniae....
To compare obstetrical and neonatal outcomes in patients with p-PROM (preterm premature rupture of membranes) at less than 30 weeks gestational age before after the application protocols developed on basis international guidelines to identify local barriers strategies for their implementation. Single twin pregnancies < gestation without signs infection were retrospectively collected. The population was divided two groups. Group A contained treated introduction protocol, hospitalized from day...