A5028245778- Neonatal and Maternal Infections
- COVID-19 Impact on Reproduction
- Maternal Mental Health During Pregnancy and Postpartum
- Antibiotic Use and Resistance
- Neonatal Respiratory Health Research
- Congenital Heart Disease Studies
- Genetic and rare skin diseases.
- Antifungal resistance and susceptibility
- Streptococcal Infections and Treatments
- Central Venous Catheters and Hemodialysis
- Antibiotics Pharmacokinetics and Efficacy
- Infant Development and Preterm Care
- Cancer and Skin Lesions
- Respiratory Support and Mechanisms
- Antibiotic Resistance in Bacteria
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Neuroscience of respiration and sleep
- COVID-19 and Mental Health
- Fungal Infections and Studies
- Enterobacteriaceae and Cronobacter Research
- Cutaneous Melanoma Detection and Management
- Vibrio bacteria research studies
- Social Sciences and Policies
- Eosinophilic Disorders and Syndromes
Hippocration General Hospital
2024
Hospital General Universitario Gregorio Marañón
2010-2023
Nationwide Children's Hospital
2022-2023
Central Ohio Radiation Oncology
2022
Weatherford College
2022
The Ohio State University
2022
Hospital Universitario de Móstoles
2018-2021
Hospital Materno-Infantil
2021
Universidad Complutense de Madrid
2021
Hospital Universitario La Paz
2019
To assess the quality of antifungal use, to propose a point score for this evaluation and estimate potential economic savings an stewardship programme. From December 2010 January 2011, we identified 100 adult inpatients receiving systemic antifungals. Antifungal use was evaluated by means predefined that considered indication, drug selection, dosage, adjustments after microbiology results, switching oral agent length treatment. Total prescriptions [in defined daily doses (DDDs) days therapy...
OBJECTIVES: To describe neonatal and maternal characteristics of the largest prospective cohort newborns from mothers with coronavirus disease 2019 (COVID-19), data which were prospectively collected nationwide registry Spanish Society Neonatology. METHODS: Between March 8, 2020, May 26, 503 neonates born to 497 diagnosed COVID-19 during pregnancy or at time delivery by 79 hospitals throughout Spain. RESULTS: Maternal symptoms similar that general population, 5% severe forms. In 45.8%...
Global assessment of antimicrobial agents prescribed to infants in the neonatal intensive care unit (NICU) may inform stewardship efforts.We conducted a one-day global point prevalence study all antimicrobials provided NICU infants. Demographic, clinical, and microbiologic data were obtained including level, census, birth weight, gestational/chronologic age, diagnoses, therapy (reason for use; length therapy), program (ASP), 30-day in-hospital mortality.On July 1, 2019, 26% (580/2,265;...
La repercusión de la infección materna por SARS-CoV-2 y su riesgo transmisión vertical es aún poco conocido. Las recomendaciones las sociedades científicas buscan proporcionar seguridad para el recién nacido sin comprometer los beneficios del contacto precoz. El objetivo estudio describir características evolución nacidos madres infectadas SARS-CoV-2, así como medidas implementadas siguiendo Sociedad Española Neonatología. Estudio observacional, prospectivo unicentro cohortes. Se diseñó un...
ABSTRACT Little information is available about pediatric infections caused by extended-spectrum-β-lactamase (ESBL)-producing Escherichia coli . We characterized an outbreak a CTX-M-14-producing E. isolate in neonatal intensive care unit (NICU) and studied other ESBL-producing non-NICU units. All children ≤4 years old who were infected or colonized isolates between January 2009 September 2010 included. Molecular epidemiology was phylogroup analysis, pulsed-field gel electrophoresis (PFGE),...
Objective: Coronavirus disease 2019 (COVID-19) cases caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue to increase worldwide. Although some data from pediatric series are available, more evidence is required, especially in neonates, a group with specific characteristics that deserve special attention. This study aimed describe general and clinical characteristics, management, treatment of postnatal-acquired (community nosocomial/hospital-acquired) COVID-19...
The impact of maternal SARS-CoV-2 infection and its risk vertical transmission is still not well known. Recommendations from scientific societies seek to provide safety for newborns without compromising the benefits early contact. aim study describe characteristics evolution born mothers with infection, as implemented measures following recommendations Sociedad Española de Neonatología. Observational, prospective single-center cohort study. A specific circuit was designed their newborns....
Whole genome sequencing has been extensively used to describe infection outbreaks, although with limited application on Candida albicans and parapsilosis.We retrospectively studied all patients admitted the neonatal care unit diagnosed candidemia caused by C. (n = 46) or parapsilosis 31) between 2007 2010 (Period 1) 2011 2014 2). All isolates were genotyped microsatellite markers. A cluster was defined as a group of ≥ 2 infected strains identical genotypes. For validation markers outbreak...
Background: Data on antifungal prescribing in neonatal patients are limited to either single-center or single-country studies 1-day recording. Therefore, we assessed longitudinal usage units (NUs) within Europe. Methods: CALYPSO, a prospective weekly point prevalence study drug NUs 18 hospitals (8 European countries), was conducted 2020 during 12-week period. All receiving systemic antifungals were included. Ward demographics collected at the beginning; ward and patient data including...
Newborns are rarely infected by extended-spectrum β-lactamase (ESBL)-producing members of the Enterobacteriaceae. In a neonatal intensive care unit, 14 newborns were or colonized CTX-M-15-producing Enterobacter cloacae. All seven patients had underlying medical conditions, and five them treated successfully with meropenem, whilst one untreated patient died. Paediatric infections caused multidrug-resistant ESBL-producing cloacae constitute critical clinical epidemiological issue.
<b>Background</b> Noninvasive ventilation is being increasingly used on preterm infants to reduce ventilator lung injury and bronchopulmonary dysplasia. The aim of this study was evaluate the effectiveness synchronized nasal intermittent positive pressure (SNIPPV) prevent intubation in premature infants. <b>Methods</b> Prospective observational SNIPPV use less than 32 weeks' gestation. All patients were managed using a prospective protocol intended invasive mechanical (iMV) use. Previous...
We report on a patient with verruciform xanthoma lesions in an epithelial nevus and developmental anomalies since birth that may be classified as CHILD syndrome (congenital hemidysplasia ichthyosiform erythroderma limb defects). Histological analyses of the lesion revealed verrucous features acanthosis, hyperkeratosis, parakeratosis typical infiltrate xanthomatous cells dermal papillae. To our knowledge only 5 cases epidermal have been reported to date. In view, present case is first which...
Antimicrobial defined daily dose (DDD), a standardized metric to assess antimicrobial consumption in adult population, has limitations hampering its use neonatal patients. This study proposes an alternative DDD design applicable for neonates.
Eruptive disseminated Spitz nevi is a rare clinical presentation that features an abrupt widespread eruption of nevi. Spontaneous regression these has been rarely reported in previous literature. The authors the present study report case 30-year-old man who presented eruptive appeared within week and started following years.
Abstract Objective. On 2/2019, the Neonatal Antimicrobial Stewardship Program at Nationwide Children’s Hospital recommended reducing empirical antibiotic therapy for early-onset sepsis (EOS) from 48 to 24 hours with a TIME-OUT. We describe our experience this guideline and assess its safety. Methods. Retrospective review of all newborns evaluated possible EOS <72 age 6 neonatal intensive care units 12/2018-7/2019. Safety endpoints were re-initiation antibiotics within 7 days after...
Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator that has demonstrated its efficacy when used to treat severe hypoxemic respiratory failure associated hypertension in term or near newborns since 1992. Premature newborn infants are not included the approved indication of iNO use, but some circumstances, been as an effective therapy improve failure. Also animal studies potential use prevent BPD, clinical trials have failed demonstrate any beneficial effect this drug routine...