A5079324881- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Drug-Induced Adverse Reactions
- Occupational exposure and asthma
- Urticaria and Related Conditions
- Autoimmune Bullous Skin Diseases
- Food Allergy and Anaphylaxis Research
- Nail Diseases and Treatments
- Asthma and respiratory diseases
- Skin Protection and Aging
- Psoriasis: Treatment and Pathogenesis
- Pesticide Exposure and Toxicity
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Eosinophilic Disorders and Syndromes
- Cutaneous lymphoproliferative disorders research
- Mast cells and histamine
- Advanced Radiotherapy Techniques
- Dermatological and COVID-19 studies
- Cutaneous Melanoma Detection and Management
- Cancer and Skin Lesions
- Hair Growth and Disorders
- Nonmelanoma Skin Cancer Studies
- Parvovirus B19 Infection Studies
- melanin and skin pigmentation
University of Bari Aldo Moro
2016-2025
IRCCS Materno Infantile Burlo Garofolo
2024
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2023
Ospedale San Bortolo
2023
Oxfam
2022
John Wiley & Sons (United States)
2022
John Wiley & Sons (United Kingdom)
2022
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2021
National Institute of Statistics
2020
University of Naples Federico II
2020
Chronic spontaneous urticaria (CSU) is defined as occurrence of wheals and/or angioedema for ≥6 weeks. Omalizumab a monoclonal anti-IgE antibody effective in refractory CSU, but its mechanism action and markers predictive response remain not completely defined.To correlate baseline levels two proposed biomarkers, total IgE (bIgE) d-dimer (bd-dimer), clinical parameters to omalizumab relapses after drug withdrawal.In this retrospective Italian multicentre study, data were collected 470 CSU...
Summary Background Allergic contact dermatitis (ACD) caused by nail acrylates, also including methacrylates and cyanoacrylates here, is being increasingly reported. Methods A retrospective study in 11 European Environmental Contact Dermatitis Research Group (EECDRG) clinics collected information on cases of ACD acrylates diagnosed aimed testing between 2013 2015. Results Among 18 228 studied patients, 136 had (0.75%; 95%CI: 0.60–0.90), representing 67.3% (95%CI: 60.4–73.7) acrylates. There...
Treatment of moderate-to-severe atopic dermatitis (AD) in the elderly may be challenging, due to side-effects traditional anti-inflammatory drugs and comorbidities often found this age group. Furthermore, efficacy safety innovative such as dupilumab are not yet well known.A multicentre retrospective, observational, real-life study on was conducted a group patients aged ≥65 years affected by severe AD. Their main clinical features were also examined.Data with (EASI ≥24) AD treated at label...
SIDeMaST (Società Italiana di Dermatologia Medica, Chirurgica, Estetica e delle Malattie Sessualmente Trasmesse) contributed to the development of present guideline on systemic treatment chronic plaque psoriasis. With permission EuroGuiDerm, adapted Italian healthcare context supply a reliable and affordable tool physicians who take care patients affected by moderate severe The content includes general information scope purpose, health questions covered, target users strength/limitations...
Moderate-to-severe atopic dermatitis (AD) in the adolescence is a high burden disease, and its treatment can be very challenging due to paucity of approved systemic drugs for this age their side-effects. Dupilumab was recently adolescent AD.A multicentre, prospective, real-world study on effectiveness safety dupilumab adolescents (aged from ≥12 <18 years) with moderate-to-severe AD conducted. The main clinical phenotypes were also examined.Data treated at label dosage 16 weeks collected....
There is limited epidemiological evidence on outcomes associated with dupilumab exposure during pregnancy; monitoring pregnancy in large populations required.
The role of palladium and nickel sensitization in oral disease dermatitis is not fully understood.To investigate whether to these metals was associated with exposure dental alloys skin complaints/symptoms a European multicentre study.In six dermatology clinics, patch tests (3% Na2 PdCl4 ; Pd = 102.0 µmol/g) (5% NiSO4 .6H2 O; Ni 190.2 were performed consecutive patients, patients' characteristics collected questionnaire clinical investigation.In total, 906 patients included, whom 24.3%...
Abstract Background Classification of hand eczema ( HE ) is mandatory in epidemiological and clinical studies, also important work. Objectives The aim was to test a recently proposed classification system practice prospective multicentre study. Methods Patients were recruited from nine different tertiary referral centres. All patients underwent examination by specialists dermatology checked using relevant allergy testing. classified into one the six diagnostic subgroups : allergic contact...
The use of methylisothiazolinone (MI) in cosmetic products has caused an unprecedented epidemic MI contact allergy. Current data concerning exposures at a European level are required.To describe demographics and for patients with allergy.Eleven dermatology departments from eight countries prospectively collected between 1 May 31 October 2015 among consecutive who had positive patch test reactions to (2000 ppm aq.).A total 6.0% (205/3434; range 2.6-13.0%) MI. Dermatitis most frequently...
Abstract Background Methylisothiazolinone (MI) has caused an unprecedented epidemic of contact allergy in Europe and elsewhere. Subsequently, regulatory action been taken, at least Europe, aiming reducing risk MI sensitization. Objective To follow‐up on the prevalence to consecutively patch tested patients assess spectrum products containing or methylchloroisothiazolinone (MCI)/MI positive which elicited current allergic dermatitis. Methods A cross‐sectional survey was performed 2016 2017,...
Background: Dupilumab has proven to be an effective treatment for patients with moderate-to-severe atopic dermatitis (AD) in clinical trials. However, real-world experience dupilumab a broader population is limited. Methods: The study comprised adult AD, defined as Eczema Area Severity Index (EASI) score of 24 or higher, treated at 10 Italian teaching hospitals. We analyzed physician-reported outcome measures (EASI), patient-reported (pruritus and sleep score, Dermatology Life Quality...
In recent years, the preferentially expressed antigen in melanoma (PRAME) has also been used histopathological diagnosis of melanocytic lesions, order to understand if it could constitute a valid, inexpensive, and useful resource dermatopathological fields. We performed double-center study evaluate whether data on usefulness possible limitations PRAME be confirmed by our group. From 1 December 2021 29 March 2022, we collected 275 cases lesions that were immunostained with (Ab219650) rabbit...
Abstract Background Eyelid dermatitis is a frequent reason of dermatological consultation. Its aetiology not univocal, being contact dermatitis, both allergic and irritant, the most frequent. The primary sources allergen exposure include cosmetics, metals, topical medications, from direct, indirect, or airborne contact. Objectives To define frequency positive patch test reactions to SIDAPA baseline series allergens, document precise final diagnosis in patients with eyelid involvement....
BACKGROUND Etiopathogenesis of nummular eczema is obscure; many causative factors have been proposed. Only a few studies investigated the relevance contact allergy. OBJECTIVE This retrospective study aimed to investigate role allergy in underlying mechanism eczema. METHODS From 29,323 consecutive patients, we patch-tested for eczematous dermatitis various type, 1022 (3.5%) with were enrolled. Data collected each patient, including age, sex, occupation, symptoms onset and duration, spread...
Summary Background The evidence on the safety of topical preparations containing botanical extracts is limited. Objectives To assess (i) use botanically derived compounds in a large population, (ii) incidence cutaneous side‐effects, and (iii) diagnostic usefulness patch testing. Methods A questionnaire was used 2661 patients to both prevalence type used, occurrence adverse skin reactions. Patients declaring reactions were tested with I talian ( SIDAPA ) baseline series, an additional...
Summary Background The prevalence of occupational and non‐occupational textile dermatitis seems to be increasing, probably because changed manufacturing techniques. Objective Evaluation the clinical features epidemiology contact ( TCD ) in I taly. Methods Demographic data, history aspects, atopy positive patch test reactions allergens were investigated 277 patients. Results Contact was most frequent presentation (95.3%). more common females, fourth fifth decades life, atopic lesions...
Salinity is one of the most severe environmental stresses, negatively affecting productivity salt-sensitive crop species. Given that germination critical phase in plant life cycle, present study aimed to determine seed potential and associated traits under salt stress conditions as a simple approach identify salt-tolerant lentil genotypes. The genetic material consisted six genotypes whose adaptation various agroclimatic not well elucidated. was applied by addition NaCl at three different...
Atopic dermatitis (AD) therapeutic approach calls for a long-term treatment. Treatment options AD have recently undergone revolutionary change by the introduction of first biologic drug. Availability in daily practice last version international guidelines, taking peculiarities country into account, can contribute to good clinical Italy. To adapt European Dermatology Forum (EDF) guidelines Italian medical–legal context, EDF were assessed independently two independent renowned experts field...