A5103179558- Cutaneous lymphoproliferative disorders research
- Cutaneous Melanoma Detection and Management
- Genetic and rare skin diseases.
- Nail Diseases and Treatments
- Autoimmune Bullous Skin Diseases
- Dermatological diseases and infestations
- Psoriasis: Treatment and Pathogenesis
- Dermatology and Skin Diseases
- Skin Protection and Aging
- Urticaria and Related Conditions
- Cancer and Skin Lesions
- Dermatological and Skeletal Disorders
- Nonmelanoma Skin Cancer Studies
- Acne and Rosacea Treatments and Effects
- Eosinophilic Disorders and Syndromes
- Allergic Rhinitis and Sensitization
- Fungal Infections and Studies
- Autoimmune and Inflammatory Disorders
- Vascular Tumors and Angiosarcomas
- Optical Coherence Tomography Applications
- Lymphoma Diagnosis and Treatment
- Vascular Malformations and Hemangiomas
- Hedgehog Signaling Pathway Studies
- Inflammasome and immune disorders
- Skin Diseases and Diabetes
University of Siena
2015-2025
Ospedale Santa Maria alle Scotte
2017-2025
Università Cattolica del Sacro Cuore
2025
Azienda Ospedaliera Universitaria Senese
1998-2024
Institute of Dermatology
2001
St George's, University of London
1996
National Public Health Laboratory
1996
Public Health Laboratory
1996
St George's Hospital
1996
SIDeMaST (Società Italiana di Dermatologia Medica, Chirurgica, Estetica e delle Malattie Sessualmente Trasmesse) contributed to the development of present guideline on systemic treatment chronic plaque psoriasis. With permission EuroGuiDerm, adapted Italian healthcare context supply a reliable and affordable tool physicians who take care patients affected by moderate severe The content includes general information scope purpose, health questions covered, target users strength/limitations...
Smartphones have overcome the limitations of image quality seen in older devices and opened a new field telemedicine called "mobile teledermatology". Technological advances need to reduce health service costs will strongly promote development telemedicine. For this reason, we evaluated concordance between store-and-forward mobile teledermatology classical face-to-face dermatological visit. We also measured time taken submit teleconsultation using smartphone. Before conventional visit,...
Extracorporeal photochemotherapy (ECP) has been shown to be a potent activator of peripheral blood macrophages because it causes marked release macrophage‐dependent proinflammatory cytokines, and is therefore currently considered safe non‐toxic immunomodulatory treatment. On this basis we studied the function mononuclear cells (PBMC) in eight patients with early stage (Ib) cutaneous T‐cell lymphoma (CTCL), before 1 year after ECP, together their clinical histological responses. In particular...
Abstract Background Few and small studies have described the management of immunomodulant/immunosuppressive therapies or phototherapy in atopic dermatitis (AD) patients during coronavirus disease 2019 (COVID‐19) pandemic. Methods A national registry, named DA‐COVID‐19 involving 35 Italian dermatology units, was established order to evaluate impact COVID‐19 pandemic on adult AD treated with systemic medications phototherapy. Demographic clinical data were obtained at different timepoints by...
Abstract Objectives To assess the lung involvement in patients with Still’s disease, an inflammatory disease assessing both children and adults. exploit possible associated factors for parenchymal these patients. Methods A multicentre observational study was arranged consecutive characterized by among those included AIDA (AutoInflammatory Disease Alliance) Network Registry. disease-lung defined presence of pleuritis, features, acute respiratory distress syndrome (ARDS), and/or pulmonary...
Background/Objectives: Facial lesions, including lentigo maligna and melanoma (LM/LMM), both malignant, present significant diagnostic challenges due to their clinical similarity benign conditions. Although standard dermoscopy is a well-established tool for diagnosis, its inability reveal cellular-level details highlights the necessity of new magnified techniques. This study aimed assess role dermoscopy, high-magnification fluorescence-advanced videodermatoscopy (FAV) in diagnosing LM/LMM...
Background/Objectives: Basal cell carcinoma (BCC) is the most common malignancy, characterised by local invasiveness and potential for tissue destruction. Diagnosing BCC can be challenging, particularly less experienced dermatologists. Line-field confocal optical coherence tomography (LC-OCT), a new noninvasive technique, has become increasingly useful in clinical practice, allowing vivo imaging at cellular resolution. This study aimed to evaluate impact of 1 h structured training session on...
Tralokinumab is a monoclonal antibody selectively targeting IL-13, approved for moderate-to-severe atopic dermatitis (AD), which real-world data are scarce. This prospective, observational, multicentric study aimed to assess the long-term effectiveness and safety of tralokinumab in patients with AD setting. Primary outcomes included 50%, 75%, 90% improvement Eczema Area Severity Index score (EASI50, EASI75, EASI90, respectively) improvements Dermatology Life Quality (DLQI) at 1 year. A total...
We report a 73-year-old male presenting with recurrent primary perianal EMPD. The patient declined both surgery and topical imiquimod preferred cryotherapy among the other available non-invasive therapeutic options. At 1-month follow-up visit, complete response to treatment was suspected on clinical dermoscopic background confirmed by LC-OCT examination, that indeed controlled efficacy demonstrating absence of Paget’s cells.For patients seeking less invasive options, LC-OCT-controlled not...
Introduction Numerous imaging techniques, such as Reflectance Confocal Microscopy (RCM), Optical Coherence Tomography (OCT), and Line-field OCT (LC-OCT), are available for skin evaluation. However, there remains a need improved methods to better understand tumor histology enhance surgical margin detection. This study aimed evaluate the quality of ex vivo LC-OCT images in cutaneous tumors, describe their morphological features, correlate findings with dermoscopy, RCM, histology. Methods: A...
Graft-versus-host disease (GVHD) is a major complication of allogeneic bone marrow transplantation. Extracorporeal photochemotherapy (ECP) has been introduced as an alternative treatment for GVHD refractory to conventional immunosuppressive treatment, although its mechanism action not yet clear. We investigated, in seven patients, the effects ECP on dendritic cell maturation and cytokine production vitro model that could mimic potential vivo effect reinfusion ECP-treated peripheral blood...
Platelet-derived products have proven useful in accelerating healing processes and tissue regeneration. However, despite their widespread use clinical practice, the cellular molecular mechanisms involved not yet been completely clarified. Recent studies show that interaction between platelet gel (PG) peripheral blood mononuclear cells (PBMC) can result activation of PBMC production several cytokines wound repair. The aim our study was to analyze whether crosstalk platelets influence by...
Frontal fibrosing alopecia (FFA) is more common in postmenopausal women, but it can occur younger women. Some authors consider FFA to be a distinct frontal variant of lichen planopilaris. From clinical point view, this relatively uncommon condition characterized by progressive frontotemporal recession due inflammatory destruction hair follicles. Dermoscopy very useful, as the differential diagnosis between traction alopecia, areata, and cicatricial marginal may difficult. It not clear...
Abstract Background Published studies on emergency dermatology consultations are few because there units in the world. No study has yet described Italian situation. Objectives To quantify and characterize patients evaluated our unit from 2006 to 2011. Methods We studied personal details, diagnosis, annual trend of cases, level hospitalization cases over 6‐year period. Results A total 12 226 were evaluated. The most numerous diagnostic group was infections (27.1%), followed by non‐specific...